Tau Control

Tau Control
  • Live
  • Mouse
  • Male & Female Available
  • Various
  • Available for direct purchase by CRO
Model No.NomenclatureGenotype
18392-FSTOCK (SW and B6D2F1)wt/wt
18392-MSTOCK (SW and B6D2F1)wt/wt
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Overview

Nomenclature: STOCK (SW and B6D2F1)

  • Wild type control stock for Tau (model #2508).
  • This model does NOT express human Tau.
  • Model is on a C57BL/6, DBA/2, SW mixed background.
  • Model was generated via a genetic refresh of model #2508. See Origin below for more information.
  • Pink eyed animals, associated with certain coat colors, and the Pde6brd1 retinal degeneration mutation can cause light sensitivity and/or blindness in some animals. This may impact the results of behavioral testing. Upon request, animals can be screened for eye color, coat color, and/or rd1 homozygosity for an additional fee.
Orders by weight: Taconic cannot accept orders by weight for this model. Please note that shipments may contain animals with a larger weight variation.

Origin

This control stock was generated via a genetic refresh of model #2508. Homozygous 2508 females were mated to Swiss Webster males. Hemizygous males from this cross were mated to B6D2F1 females. Wild type offspring from this second cross were used to establish control model #18392, whereas hemizygous males and females were intracrossed to generate homozygous mice to re-establish model #2508.

Genetics

Species:Mouse
Strain Type:Outbred or Mixed
Coat Color:Various
Genetic Background:Mixed

Other Genetic Notes:

Wild type for Nnt mutation; carries Pde6brd1 mutation.

Guides & Publications

Applications & Therapeutic Areas

  • Neuroscience
  • "Alzheimers Disease"

Transit, Housing & Welfare

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Packing Practices

Taconic standard practice is to recombine animals of different home cages and/or ages from a single model and sex during packing, except in specific cases where Taconic's animal welfare policy prohibits recombination due to aggression or other concerns.  When an order is fulfilled with animals from more than one week of birth, this standard practice results in animals from a range of birth weeks packed together in a single TTC. When an order is fulfilled with animals from genotyped models, this standard practice results in animals from different home cages packed together in a single TTC.

Customers who wish to keep animals from different weeks of birth separated should place orders with the special instruction "Divide and label by age."  Note that this special request can result in increased costs for additional Taconic Transit Cages, dividers and/or freight charges.

Tau Control

Conditions of Use for Taconic Transgenic Models™

Taconic Transgenic Models™ (Models) are produced and distributed under rights to patents and intellectual property licensed from various institutions. Taconic sells the Models to purchasers, grants to each purchaser a right under Taconic's rights in such licensed patents and intellectual property to use the purchased Model in consideration of purchasers' acknowledgement of and agreement to the Terms and Conditions for Taconic Models, Products and Services and the following terms of use:

  • Title to these Models and biological materials derived from them remains with Taconic.
  • The Models will be used for research purposes only.
  • The Models will not be bred or cross-bred except to obtain embryos or fetuses required for research purposes unless additional rights have been granted in writing by Taconic.
  • The Models and biological materials derived from them will not be distributed to third parties or used for commercial purposes.
  • Non-profit purchasers may not use this Model and/or biological materials derived from it in sponsored research or contract research studies unless it is purchased at the for-profit price.

Pricing - USD

Murine Pathogen Free (MPF) Health Standard

18392 Female

18392-F Genotype wt/wt

Age in WeeksQuantity 1 - 999
3 to 10$556.00

18392 Male

18392-M Genotype wt/wt

Age in WeeksQuantity 1 - 999
3 to 10$556.00

Pricing - EUR

Murine Pathogen Free (MPF) Health Standard

18392 Female

18392-F Genotype wt/wt

Age in WeeksQuantity 1 - 999
3 to 10€486,00

18392 Male

18392-M Genotype wt/wt

Age in WeeksQuantity 1 - 999
3 to 10€486,00

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