Be ABLE to focus on the research
The ABLE™ Program — Access to Breeding with License-fee Exemption — waives breeding license fees on eligible validated models, so you can breed and crossbreed them at Taconic without a separate breeding license fee standing between you and your study.
The Taconic ABLE™ Program waives breeding license fees on eligible genetically engineered models (GEMs) available from Taconic, so qualifying breeding and crossbreeding performed at Taconic proceeds without a separate per-project breeding license fee.
ABLE waives the breeding license fee for qualifying breeding and crossbreeding at Taconic. A licensing framework still governs the work — ABLE removes the fee barrier, not the need for defined terms. Standard model purchases do not, on their own, convey breeding rights.
The intent is straightforward: keep your attention on the biology, the model cross your study requires, and the downstream work — while Taconic manages the breeding.
Many research programs require more than a single model. When a study depends on combining a validated translational model with a research-specific line, licensing terms and project setup can create friction before the science moves forward.
ABLE reduces that friction in three ways that matter to study design:
When your research question calls for a specific model combination, ABLE supports the path from model selection to breeding at Taconic — without a breeding license fee as a gating step.
ABLE supports breeding and crossbreeding of eligible models with your research-specific, custom-generated, or other applicable models.
Start from eligible validated models with known genetic foundations and translational relevance to specific research questions — a defined foundation for the cross your study depends on.
A team running an immuno-oncology study needs an HLA-transgenic background crossed with their own tumor-model line. Rather than managing the model cross independently, the team identifies an ABLE-eligible HLA line, crosses it with the research-specific line at Taconic, and works with Taconic to generate cohorts aligned to the study plan — with the breeding license fee waived.
By reducing the upfront cost of starting a breeding project, enABLE helps researchers access ABLE-eligible GEMs while supporting efficient project initiation through Taconic Colony Management Solutions.
Eligible customers may receive up to 40 animals at no charge for use in a qualifying ABLE-supported CMS project.
The promotion is intended to support the initiation of qualifying ABLE projects at Taconic.
Standard Colony Management fees, husbandry charges, breeding costs, shipping charges, and other applicable service fees remain the responsibility of the customer.
The enABLE Promotion is available for qualifying projects initiated between August 3, 2026 and December 31, 2026
To qualify for the promotion:
The genetically engineered models below are available from Taconic and eligible for breeding at Taconic with breeding license fees waived through the ABLE Program. For qualifying projects, eligible models may be bred or crossbred at Taconic — including with customer-supplied, custom-generated, or other applicable research-specific models.
Some models are relevant to more than one research area. These groupings are non-exhaustive and overlapping — they are intended to help you locate ABLE-eligible models aligned with your scientific focus.
Alzheimer's disease, Parkinson's disease, and other neurobiology-focused work.
Transporter biology, blood-brain barrier work, and transporter-associated genetic backgrounds.
Cardiometabolic disease, lipid metabolism, APOE biology, and incretin-related work.
Antigen presentation, immune response and mechanism research, oncology and immuno-oncology, and immune-modified model work.
| Model Number | Model Name |
|---|---|
4149 | Abb Knockout/Transgenic HLA-DR4 |
1004 | ApoB100 |
APOE | APOE KO |
1547 | Human APOE2 KI |
1548 | Human APOE3 KI |
1549 | Human APOE4 KI |
16347 | APP/PS1 (ARTE10) |
1349 | APPswe |
2469 | APPswe-Tau |
22964 | aSyn A53T SNCA |
22966 | aSyn SNCA KO |
2767 | Bcrp |
3715 | CETP |
3716 | CETP-ApoB100 |
584 | Fcer1g (BALB/c) |
583 | Fcer1g (C57BL/6) |
580 | Fcgr2b (C57BL/6) |
21546 | Floxed Prkn |
23662 | hCD98hc Mouse |
23660 | hGLP1R |
9662 | HLA-A1 |
8909 | HLA-A1 (C57BL/6) |
9660 | HLA-A11 |
8907 | HLA-A11 (C57BL/6) |
9659 | HLA-A2.1 |
8906 | HLA-A2.1 (C57BL/6) |
9663 | HLA-A24 |
8910 | HLA-A24 (C57BL/6) |
9664 | HLA-B44 |
8911 | HLA-B44 (C57BL/6) |
9661 | HLA-B7 |
8908 | HLA-B7 (C57BL/6) |
23236 | hTFRC |
11026 | Human 22q11.2 Deletion [Df(h22q11)/+] Mouse |
1147 | Jh (BALB/c) |
13940 | LRRK2 G2019S |
MDR1A | MDR1A KO |
3998 | Mdr1a/b-Bcrp |
22640 | PINK1 KO |
22574 | Rab32 S69R KI |
4111 | RAG2 Il2RG |
601 | RAG2 KO (BALB) |
2334 | RAG2 KO/OT-I |
11490 | RAG2 KO/OT-II |
RAGN12 | RAG2 KO (B6) |
2148 | SOD1 Rat |
2045 | Stat1 |
2508 | Tau |
18392 | Tau Control |
1006 | TNF-α |
Access to Breeding with License-fee Exemption.
ABLE waives breeding license fees on eligible genetically engineered models available from Taconic, so qualifying breeding and crossbreeding performed at Taconic proceeds without a separate per-project breeding license fee.
ABLE helps you move from model need to model cross without a breeding license fee as a gating step. Qualifying breeding and crossbreeding is performed at Taconic through CMS, so your focus stays on the biology, the required combination, and downstream objectives.
No. ABLE waives the breeding license fee for qualifying work involving eligible models at Taconic. A licensing framework still governs the work; the program does not create unrestricted breeding rights.
For eligible models and qualifying breeding or crossbreeding performed at Taconic, breeding license fees are waived. Standard CMS fees, husbandry, breeding, shipping, and other applicable service fees still apply.
No. ABLE applies only to eligible models. The eligible-model list on this page identifies which models can be bred or crossbred at Taconic with breeding license fees waived.
In qualifying projects, yes — an ABLE-eligible model may be crossbred with a research-specific, custom-generated, or other applicable research-specific line when the work is performed at Taconic.
Customer-supplied lines can be incorporated in qualifying crosses at Taconic. Specific constraints are confirmed during project scoping.
No. ABLE applies to qualifying breeding and crossbreeding performed at Taconic. Standard model purchases do not provide unrestricted breeding rights.
ABLE is available to both non-profit and for-profit researchers for qualifying models.
Timelines depend on the models involved, the cross required, and cohort size. Taconic provides a project-specific timeline during planning through CMS.
Contact Taconic to discuss whether your model, planned cross, or breeding project may qualify for ABLE.
The ABLE™ Program applies to eligible models and qualifying breeding or crossbreeding performed at Taconic. Standard model purchases do not provide unrestricted breeding rights. Eligibility is subject to model qualification, planned cross, and applicable licensing terms.
If your research requires a validated model crossed with a research-specific line, custom-generated, or other applicable line, ask whether your project qualifies for ABLE-supported breeding at Taconic with breeding license fees waived.
