Gene Expression Analysis
Gene expression profiling is a critical tool for validating, monitoring, and understanding genetically engineered models. Taconic's Gene Expressions Services enables researchers to confirm the fidelity, monitor gene expression changes over time, and generate molecular insights that strengthen study outcomes.
Taconic Biosciences provides a fast, flexible, and insight-driven gene expression profiling service designed to support preclinical research from start to finish. With laboratories in both Europe and the US, we offer global access to a harmonized gene expression platform. Our customizable assay design, including flexible housekeeping gene selection and support for a wide range of tissues and cell types, paired with expert scientific interpretation, ensures you receive high-quality data that accelerates discovery.
Key Applications
Our gene expression services support a variety of applications, including:
Model Validation: Confirm that your genetic modification is expressed at the levels you expect in the tissues you desire.
Baseline Profiling: Establish pre-intervention expression references in tissues or cells of interest.
Post-Intervention/Study Readouts: Quantitatively assess how treatments or manipulations alter gene expression.
Why Taconic?
Taconic Biosciences is a global leader in genetically engineered mouse models and colony management services. We support researchers in advancing their science with innovative, reliable solutions.
Learn More about our Fully Integrated Custom Model Generation and Colony Management Solutions.
Have Questions About Gene Expression Analysis?
Learn how gene expression analysis can advance your work. Reach out to our team of scientific experts to discuss your specific research needs.
Why Choose Taconic for Gene Expression Profiling?
Taconic Biosciences delivers gene expression analysis designed for speed, flexibility, and meaningful scientific insight:
- Global Infrastructure: Access gene expression services through our US and EU laboratories, enabling regional support, reliable scheduling, and consistent quality.
- Fast Timeline: Receive complete results in as little as 4-6 weeks from tissue collection through report generation.
- Scientific Flexibility: Customize your study with tailored assay design, including housekeeping gene selection, tissue panel development, and comparison groups aligned with your research goals.
- Depth of Insights: Get more than raw data. Our reports provide detailed analyses, model-specific comparisons, and clear scientific interpretation to help you understand biological relevance and make confident decisions.
Gene Expression Analysis Workflow
Our streamlined workflow integrates controlled sample handling, robust quantitative assays, and expert analysis to produce reliable and interpretable gene expression results.
1. Define Your Study Design:
What model(s), tissues, comparison groups, and housekeeping controls do you want?
2. Tissue Collection:
Samples are collected and prepared at one of our laboratories in the USA, Germany, or Denmark.
3. Sample Shipment:
We manage all logistics to ensure the secure and efficient transfer of tissue samples from collection sites to molecular analysis labs.
4. Expression Assay:
RNA is processed, and quantitative assays (qPCR or ddPCR) are performed using selected housekeeping genes across your tissues or cells.
5. Analysis & comparatives:
Data are normalized, statistical analyses performed, and comparisons made (e.g., treated vs. baseline, wild-type vs. mutant
6. Report & Interpretation:
You receive a complete report with visuals (charts, raw data), statistical summaries, and interpretation tailored to your model and/or study.
What is Gene Expression?
Gene expression analysis enables researchers to gain insight into genes that are either active or shut off in a particular biological condition. Through the measurement of RNA levels in specific tissues or cells, scientists can determine how genetic changes, treatments, or disease states affect molecular pathways. This approach offers a clearer view of what's happening inside a model at the cellular level. When combined with reliable mouse models, gene expression analysis becomes a strong means to link genetic alterations to actual biological outcomes.
How Can Researchers Use Gene Expression in Their Studies?
Researchers use gene expression analysis to understand how genes are activated or suppressed under specific conditions, disease states, or treatments. By measuring RNA levels across tissues or cell types, scientists can identify biomarkers, validate genetically engineered models, and confirm target engagement for therapeutic programs. Gene expression studies also help researchers compare wild-type and mutant phenotypes, track disease progression, and evaluate the impact of drug candidates with precise, quantitative data. This makes gene expression a powerful tool for advancing preclinical research and accelerating the discovery of new drugs.
Have Questions About Gene Expression Analysis?
Learn how gene expression analysis can advance your work. Reach out to our team of scientific experts to discuss your specific research needs.