ExpressMODEL® Embryonic Stem Cell Platform

introduction to embryo

Traditional Mouse Model Generation

Traditional mouse model generation takes, on average, a staggering 70 weeks as generation of enough experimental animals requires at least two to three generations of breeding. So far, most efforts to reduce timelines have been focused on expediting the genome modification steps by decreasing the level of controls applied to the genome engineering procedures. This can increase the risk of introducing unwanted mutations in addition to the desired change in the targeted allele.

ExpressMODEL® Platform

The ExpressMODEL® Platform for Embryonic Stem Cell based custom model generation projects is a novel approach developed by Taconic Biosciences to reduce the timelines to experimental cohort delivery from 70 weeks to 54 weeks. By leveraging recent advancement in gene targeting and In Vitro Fertilization (IVF) technologies, ExpressMODEL® service enables the RapidEXPANSION™ of founder mice carrying the targeted alleles from 3-5 animals to at least 20-50 animals in the first generation, therefore bypassing at least one round of colony expansion, saving researchers 3-4 months on overall project timelines.

express model timeline

Why choose the ExpressMODEL® option?

Perform your in vivo experiments faster by:

  • Reducing timelines to results by 3-4 months
  • Directly generating mice at any desired health status
  • Increasing flexibility of cohort size tailored to your research needs
  • Maintaining stringent quality controls throughout projects

We’re Here to Help

Experience & Expertise You Can Trust

Taconic Biosciences' model generation team has produced about 5,000 models in the last 15 years, developing a globally-recognized reputation for advancing the work of in vivo researchers. Our scientific program managers are here to help you navigate the complexities of model generation.

Pricing Guide

Get In Touch

Book a complimentary consultation or get support for an existing order

If you need immediate assistance, please contact Customer Service:

Taconic Corporate Offices

Phone: +1 (518) 697-3900
273 Hover Ave., Germantown, NY 12526

North American Customer Service

Phone: +1 (518) 697-3915 
Toll-free:  +1 (888) 822-6642

Hours: (Monday - Friday): 7 a.m. - 6 p.m. ET

European Customer Service

Phone (Europe and Denmark): +45 70 23 04 05 
Phone (Germany): +49 214 50 68 023 
Hours: (Monday - Friday): 7 a.m. - 5 p.m. CET

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