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Development of Human NK Cells in NOG-hIL-2 and NOG-hIL-15 Tg Mice

Thursday, October 25
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Speed Congenics or Accelerated Backcrossing

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  • Investigating Tauopathies with Transgenic Mice

    In a recent manuscript by Musi and co-authors, a combinatorial approach was adopted to investigate the tauopathy-mediated mechanisms underlying human Alzheimer's Disease (AD) in post-mortem human brain tissue and transgenic mice1. Human neurodegenerative diseases comprise a heterogenous group of disorders, underpinned by complex interactions of... Read more

  • 2018 Nobel Prize in Physiology or Medicine Awarded to Two Immunologists

    Source: Karolinska Institutet On Monday, October 1, 2018 the Nobel Committee announced the recipients of this year's Nobel Prize in Physiology or Medicine. The two Nobel laureates were James P. Allison — a professor and immunologist from MD Anderson Cancer Center — and Tasuku Honjo... Read more

  • Transgenic Mice Play a Key Role in Global Polio Eradication Initiative (GPEI)

    Humanity is on the verge of one of the greatest public health achievements in history — eradicating polio. The Global Polio Eradication Initiative (GPEI) has reduced polio cases by 99.9% since 1988, bringing the world closer than ever to ending polio for good. This means... Read more

  • Webinar Q&A — Cyclical Bias

    In a recent webinar, Dr. Alex Rodriguez-Palacios of Case Western Reserve University School of Medicine discussed a confounding influence on many common microbiome study endpoints uncovered in studies using the NesTiso system. The NesTiso system has been described in a previous publication1 and examined in... Read more

  • Breast Cancer Awareness Month

    October is National Breast Cancer Awareness Month. There is a lot to be excited about this year as mortality rates continue to drop for major cancer types, including breast cancer. Between 1989 and 2015 deaths from breast cancer specifically declined 39%, a decline American Cancer... Read more

  • Mountain Cottages, Fresh Air, and TB Research

    A Tuberculosis Directory by Philip P. Jacobs. 1911. National Association for the Study and Prevention of Tuberculosis. After centuries of research tuberculosis (TB) has dropped from one of the leading causes of death in the 19th century to the ninth, worldwide. How did we accomplish... Read more

  • Pancreatic Cancer Microbiome Suppresses Immune Responses

    Alterations in the microbiome have an acknowledged role in cancer pathology1,2. Earlier this year, however, researchers at New York University published a manuscript3 connecting the pancreatic microbiome to cancer progression. In this report, Pushalkar et al. demonstrate that the endogenous microbiome of the pancreas can... Read more

  • Round Up: Top 5 Insights from the Summer 2018

    Here's our recap of the top Insight posts from the summer you might have missed! 1. Translational Microbiome Infographic Are you beginning your studies in the Microbiome and don't know where to start? Download and print out the Translational Microbiome at a Glance Infographic to... Read more