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Breed Vs. Buy: What's The Right Choice For Your Lab?

Monday, July 20
at 11 a.m. ET / 5 p.m. CET

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  • An update on mouse kidney parvovirus

    The kidneys of immunodeficient mice infected with MKPV appear pale and shrunken on gross necropsy. Histology reveals significant fibrosis. Source: Roediger et al. Cell 20181 It's been over 18 months since mouse kidney parvovirus (MKPV) was identified as a novel pathogen causing inclusion body nephropathy... Read more

  • Mouse-adapted SARS-CoV-2 strains unlock broader mouse modeling of COVID-19

    COVID-19 modeling in mice has been limited by species differences in the ACE2 protein between mice and humans. The SARS-CoV-2 virus uses the ACE2 protein to facilitate entry into cells. The mouse ACE2 receptor is not permissive for viral binding, and thus initial reports indicate... Read more

  • Transgenic hACE2 mice for SARS-CoV-2 and COVID-19

    There is an urgent need to find mouse models to support the development of SARS-CoV-2 vaccines and therapeutics and combat the COVID-19 pandemic. A recent study from Peking Union Medical College has demonstrated the promising application of humanized angiotensin converting enzyme 2 (ACE2) transgenic mice... Read more

  • Taconic's Guide to the AACR Virtual Annual Meeting II

    This year the second part of the American Association for Cancer Research's (AACR) Annual Meeting will be held virtually from June 22nd-24th. While the in-person annual AACR conference attracts over 23,000 researchers in multiple fields, the virtual meeting attendance could be even higher with free... Read more

  • Webinar Q&A - Beyond HSCs: Humanized Immune System Models Based on PBMCs and Isolated Immune Cell Subsets

    Dr. Paul Volden recently presented a webinar on humanized immune system mouse models, focusing on engraftment of PBMCs and isolated cell subsets. Taconic has extensive experience with humanized mice, both from internal research as well as many collaborations with external partners. Although hematopoietic stem cell-engrafted... Read more

  • Taconic Biosciences Learn at Home Series: Inflammatory Bowel Disease (IBD)

    With many researchers and laboratory animal professionals under orders to remain at home to limit the spread of coronavirus, we know you may have a bit more time on your hands than usual. To help keep you engaged while working from home, Taconic Biosciences has... Read more

  • Understanding Malocclusion in Research Mice

    The word rodent is derived from the Latin word rodere, which means "to gnaw". This process of gnawing brings to light common dental maladies that are of paramount importance to animal welfare. One specific condition is called malocclusion, which is caused by the misalignment of... Read more

  • Microbial Metabolism of Bile Acids Contributes to Immunological Balance in the Colon

    Regulatory T (Treg) lymphocytes play an essential role in maintaining homeostasis of the immune system. Characterized by expression of the forkhead box transcription factor (Foxp3), populations of Tregs are divided into two subsets: thymus-derived, or natural Treg cells (nTreg), peripheral Treg cells (pTreg), or induced... Read more