Neurobiology Video Series

Neuroscience research is evolving rapidly, bringing new opportunities and challenges in disease modeling, colony management, breeding strategy, and translational discovery. In this video series, Taconic's scientific experts share practical insights drawn from their hands-on experience supporting researchers in biotech, pharmaceutical, and academic organizations.

Episode 1

What's New in Alzheimer's Disease Modeling?

Alzheimer's disease is highly heterogeneous, making it difficult for any single preclinical model to capture the full complexity of human disease biology and therapeutic response. In this episode, Dr. Janell Richardson explores emerging approaches to Alzheimer's disease modeling and discusses how advanced preclinical platforms can help researchers investigate genotype-dependent differences and improve translational relevance.


Episode 2

Why Are Neurological Mouse Models So Difficult to Breed?

Producing study-ready cohorts of neurological disease models often requires careful planning around breeding performance, phenotype development, aging, and attrition. In this episode, Dr. Caroline Mallick-Wood shares insights for anticipating these challenges and designing breeding programs that support neuroscience research.


Video

Episode 3—Coming Soon

When Breeding Neuroscience In Vivo Models Doesn’t Go As Planned

Even the most carefully designed neurological disease breeding programs can face unexpected challenges that threaten study timelines, cohort availability, and research outcomes. In this episode, Dr. Gretchen Kusek shares practical strategies for anticipating risk, managing biological variability, and building contingency plans that help keep complex neuroscience research programs on track.


Additional Resources


APOE3xARTE10 & APOE4xARTE10 APP/PS1 Alzheimer’s Models

Evaluate amyloid pathology, plaque-associated glial response, and APOE genotype effects using APOE3xARTE10 and APOE4xARTE10 human APOE APP/PS1 Alzheimer’s disease models.
Neurobiology

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