TSG-p53® - Model P53N5 Publications

TSG-p53® - Model P53N5 Model Page

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Toledo F, et al.
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Toledo F, Liu CW, Lee CJ, Wahl GM
(2006) RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses. Nucleic Acids Res. 34(13):e92
Pritchard JB, et al.
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Pritchard JB, French JE, Davis BJ, Haseman JK
(2003) The role of transgenic mouse models in carcinogen identification. Environ. Health Perspect. 111(4):444-54
Johansson FK, et al.
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Johansson FK, Brodd J, Eklöf C, Ferletta M, Hesselager G, Tiger CF, Uhrbom L, Westermark B
(2004) Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging. Proc. Natl. Acad. Sci. U.S.A. 101(31):11334-7
Oncology
Horn TL, et al.
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Horn TL, Cwik MJ, Morrissey RL, Kapetanovic I, Crowell JA, Booth TD, McCormick DL
(2007) Oncogenicity evaluation of resveratrol in p53(+/-) (p53 knockout) mice. Food Chem. Toxicol. 45(1):55-63
Oncology
Ferguson DO, et al.
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Ferguson DO, Sekiguchi JM, Chang S, Frank KM, Gao Y, DePinho RA, Alt FW
(2000) The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. Proc. Natl. Acad. Sci. U.S.A. 97(12):6630-3
Donehower LA, et al.
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Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA, Butel JS, Bradley A
(1992) Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356(6366):215-21
Bielas JH, et al.
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Bielas JH, Heddle JA
(2003) Elevated mutagenesis and decreased DNA repair at a transgene are associated with proliferation but not apoptosis in p53-deficient cells. Proc. Natl. Acad. Sci. U.S.A. 100(22):12853-8
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