TNF-α Publications

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Liao X, et al.
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Liao X, Liang H, Pan J, Zhang Q, Niu J, Xue C, Ni J, Cui D		 (2021) Preparation and characterization of a fully human monoclonal antibody specific for human tumor necrosis factor alpha. Bioengineered 12(2):10821-10834
Chen YH, et al.
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Chen YH, Liu RH, Cui YZ, Hettinghouse A, Fu WY, Zhang L, Zhang C, Liu CJ		 (2022) Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases. Arthritis Res Ther 24(1):27
Beckford-Vera DR, et al.
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Beckford-Vera DR, Gonzalez-Junca A, Janneck JS, Huynh TL, Blecha JE, Seo Y, Li X, VanBrocklin HF, Franc BL		 (2020) PET/CT Imaging of Human TNFα Using [Zr]Certolizumab Pegol in a Transgenic Preclinical Model of Rheumatoid Arthritis. Mol Imaging Biol 22(1):105-114
Gorth DJ, et al.
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Gorth DJ, Ottone OK, Shapiro IM, Risbud MV		 (2020) Differential Effect of Long-Term Systemic Exposure of TNFα on Health of the Annulus Fibrosus and Nucleus Pulposus of the Intervertebral Disc. J Bone Miner Res 35(4):725-737
Kishimoto TK, et al.
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Kishimoto TK, Ferrari JD, LaMothe RA, Kolte PN, Griset AP, O'Neil C, Chan V, Browning E, Chalishazar A, Kuhlman W, Fu FN, Viseux N, Altreuter DH, Johnston L, Maldonado RA		 (2016) Improving the efficacy and safety of biologic drugs with tolerogenic nanoparticles. Nat Nanotechnol 11(10):890-899
Lu YC, et al.
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Lu YC, Chuang CH, Chuang KH, Chen IJ, Huang BC, Lee WH, Wang HE, Li JJ, Cheng YA, Cheng KW, Wang JY, Hsieh YC, Lin WW, Cheng TL		 (2019) Specific activation of pro-Infliximab enhances selectivity and safety of rheumatoid arthritis therapy. PLoS Biol. 17(6):e3000286
Rheumatoid Arthritis
Velasco-Velázquez MA, et al.
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Velasco-Velázquez MA, Salinas-Jazmín N, Hisaki-Itaya E, Cobos-Puc L, Xolalpa W, González G, Tenorio-Calvo A, Piña-Lara N, Juárez-Bayardo LC, Flores-Ortiz LF, Medina-Rivero E, Pérez NO, Pérez-Tapia SM		 (2017) Extensive preclinical evaluation of an infliximab biosimilar candidate. Eur J Pharm Sci 102:35-45
Ochi S, et al.
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Ochi S, Shinohara M, Sato K, Gober HJ, Koga T, Kodama T, Takai T, Miyasaka N, Takayanagi H		 (2007) Pathological role of osteoclast costimulation in arthritis-induced bone loss. Proc. Natl. Acad. Sci. U.S.A. 104(27):11394-9
Hayward MD, et al.
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Hayward MD, Jones BK, Saparov A, Hain HS, Trillat AC, Bunzel MM, Corona A, Li-Wang B, Strenkowski B, Giordano C, Shen H, Arcamone E, Weidlick J, Vilensky M, Tugusheva M, Felkner RH, Campbell W, Rao Y, Grass DS, Buiakova O		 (2007) An extensive phenotypic characterization of the hTNFalpha transgenic mice. BMC Physiol. 7:13
Gilbert LC, et al.
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Gilbert LC, Chen H, Lu X, Nanes MS		 (2013) Chronic low dose tumor necrosis factor-α (TNF) suppresses early bone accrual in young mice by inhibiting osteoblasts without affecting osteoclasts. Bone 56(1):174-83
Ghosh S, et al.
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Ghosh S, Hoenerhoff MJ, Clayton N, Myers P, Stumpo DJ, Maronpot RR, Blackshear PJ		 (2010) Left-sided cardiac valvulitis in tristetraprolin-deficient mice: the role of tumor necrosis factor alpha. Am. J. Pathol. 176(3):1484-93
Delavallée L, et al.
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Delavallée L, Semerano L, Assier E, Vogel G, Vuagniaux G, Laborie M, Zagury D, Bessis N, Boissier MC		 (2009) Active immunization to tumor necrosis factor-alpha is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis. Arthritis Res. Ther. 11(6):R195
Delavallée L, et al.
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Delavallée L, Le Buanec H, Bessis N, Assier E, Denys A, Bizzini B, Zagury D, Boissier MC		 (2008) Early and long-lasting protection from arthritis in tumour necrosis factor alpha (TNFalpha) transgenic mice vaccinated against TNFalpha. Ann. Rheum. Dis. 67(9):1332-8
Charles JF, et al.
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Charles JF, Hsu LY, Niemi EC, Weiss A, Aliprantis AO, Nakamura MC		 (2012) Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. J. Clin. Invest. 122(12):4592-605
Burri L, et al.
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Burri L, Bjørndal B, Wergedahl H, Berge K, Bohov P, Svardal A, Berge RK		 (2011) Tetradecylthioacetic acid increases hepatic mitochondrial β-oxidation and alters fatty acid composition in a mouse model of chronic inflammation. Lipids 46(8):679-89
Bjørndal B, et al.
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Bjørndal B, Vik R, Brattelid T, Vigerust NF, Burri L, Bohov P, Nygård O, Skorve J, Berge RK		 (2012) Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet. Metab. Clin. Exp. 61(10):1461-72
Bjørndal B, et al.
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Bjørndal B, Burri L, Wergedahl H, Svardal A, Bohov P, Berge RK		 (2012) Dietary supplementation of herring roe and milt enhances hepatic fatty acid catabolism in female mice transgenic for hTNFα. Eur J Nutr 51(6):741-53
Bjørndal B, et al.
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Bjørndal B, Berge C, Ramsvik MS, Svardal A, Bohov P, Skorve J, Berge RK		 (2013) A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation. Lipids Health Dis 12:143
Biton J, et al.
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Biton J, Semerano L, Delavallée L, Lemeiter D, Laborie M, Grouard-Vogel G, Boissier MC, Bessis N		 (2011) Interplay between TNF and regulatory T cells in a TNF-driven murine model of arthritis. J. Immunol. 186(7):3899-910
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