Tau - Model 2508 Publications

Tau - Model 2508 Model Page

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Chai X, et al.
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Chai X, Wu S, Murray TK, Kinley R, Cella CV, Sims H, Buckner N, Hanmer J, Davies P, O'Neill MJ, Hutton ML, Citron M
(2011) Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression. J. Biol. Chem. 286(39):34457-67
Neuroscience, Alzheimer's
Bi M, et al.
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Bi M, Ittner A, Ke YD, Götz J, Ittner LM
(2011) Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice. PLoS ONE 6(12):e26860
Neuroscience, Alzheimer's
Asuni AA, et al.
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Asuni AA, Boutajangout A, Quartermain D, Sigurdsson EM
(2007) Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements. J. Neurosci. 27(34):9115-29
Neuroscience, Alzheimer's
Lasagna-Reeves CA, et al.
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Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R
(2014) The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta Neuropathol Commun 2:56
Neuroscience, Alzheimer's
Nilson AN, et al.
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Nilson AN, English KC, Gerson JE, Whittle TB, Crain CN, Xue J, Sengupta U, Castillo-Carranza DL, Zhang W, Gupta P, Kayed R
(2016) Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases. J. Alzheimers Dis.
Neuroscience, Alzheimer's
Castillo-Carranza DL, et al.
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Castillo-Carranza DL, Sengupta U, Guerrero-Muñoz MJ, Lasagna-Reeves CA, Gerson JE, Singh G, Estes DM, Barrett AD, Dineley KT, Jackson GR, Kayed R
(2014) Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. J. Neurosci. 34(12):4260-72
Neuroscience, Alzheimer's
Lewis J, et al.
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Lewis J, McGowan E, Rockwood J, Melrose H, Nacharaju P, Van Slegtenhorst M, Gwinn-Hardy K, Paul Murphy M, Baker M, Yu X, Duff K, Hardy J, Corral A, Lin WL, Yen SH, Dickson DW, Davies P, Hutton M
(2000) Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25(4):402-5
Halverson RA, et al.
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Halverson RA, Lewis J, Frausto S, Hutton M, Muma NA
(2005) Tau protein is cross-linked by transglutaminase in P301L tau transgenic mice. J. Neurosci. 25(5):1226-33
Chen F, et al.
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Chen F, Wollmer MA, Hoerndli F, Münch G, Kuhla B, Rogaev EI, Tsolaki M, Papassotiropoulos A, Götz J
(2004) Role for glyoxalase I in Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 101(20):7687-92
Alzheimer's