Rag2 - Model RAGN12 Publications

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Zhang K, et al.
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Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ
(2005) The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J. Clin. Invest. 115(2):268-81
T And/Or B Cell Function
Xiao H, et al.
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Xiao H, Heeringa P, Hu P, Liu Z, Zhao M, Aratani Y, Maeda N, Falk RJ, Jennette JC
(2002) Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J. Clin. Invest. 110(7):955-63
Witt CM, et al.
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Witt CM, Raychaudhuri S, Schaefer B, Chakraborty AK, Robey EA
(2005) Directed migration of positively selected thymocytes visualized in real time. PLoS Biol. 3(6):e160
Sommers CL, et al.
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Sommers CL, Lee J, Steiner KL, Gurson JM, Depersis CL, El-Khoury D, Fuller CL, Shores EW, Love PE, Samelson LE
(2005) Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection. J. Exp. Med. 201(7):1125-34
Singh NJ, et al.
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Singh NJ, Chen C, Schwartz RH
(2006) The impact of T cell intrinsic antigen adaptation on peripheral immune tolerance. PLoS Biol. 4(11):e340
T And/Or B Cell Function
Min B, et al.
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Min B, Foucras G, Meier-Schellersheim M, Paul WE
(2004) Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire. Proc. Natl. Acad. Sci. U.S.A. 101(11):3874-9
T And/Or B Cell Function
Milner JD, et al.
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Milner JD, Ward JM, Keane-Myers A, Paul WE
(2007) Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease. Proc. Natl. Acad. Sci. U.S.A. 104(2):576-81
T And/Or B Cell Function
Krueger A, et al.
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Krueger A, von Boehmer H
(2007) Identification of a T lineage-committed progenitor in adult blood. Immunity 26(1):105-16
Kojima H, et al.
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Kojima H, Gu H, Nomura S, Caldwell CC, Kobata T, Carmeliet P, Semenza GL, Sitkovsky MV
(2002) Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha -deficient chimeric mice. Proc. Natl. Acad. Sci. U.S.A. 99(4):2170-4
Huang YH, et al.
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Huang YH, Li D, Winoto A, Robey EA
(2004) Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals. Proc. Natl. Acad. Sci. U.S.A. 101(14):4936-41
T And/Or B Cell Function
Erlebacher A, et al.
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Erlebacher A, Zhang D, Parlow AF, Glimcher LH
(2004) Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system. J. Clin. Invest. 114(1):39-48
Erlebacher A, et al.
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Erlebacher A, Vencato D, Price KA, Zhang D, Glimcher LH
(2007) Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. J. Clin. Invest. 117(5):1399-411
Chan WF, et al.
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Chan WF, Perez-Diez A, Razavy H, Anderson CC
(2007) The ability of natural tolerance to be applied to allogeneic tissue: determinants and limits. Biol. Direct 2:10
Acuff HB, et al.
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Acuff HB, Carter KJ, Fingleton B, Gorden DL, Matrisian LM
(2006) Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment. Cancer Res. 66(1):259-66
Zúñiga-Pflücker JC, et al.
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Zúñiga-Pflücker JC, Jiang D, Schwartzberg PL, Lenardo MJ
(1994) Sublethal gamma-radiation induces differentiation of CD4-/CD8- into CD4+/CD8+ thymocytes without T cell receptor beta rearrangement in recombinase activation gene 2-/- mice. J. Exp. Med. 180(4):1517-21
Yang L, et al.
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Yang L, Bailey L, Baltimore D, Wang P
(2006) Targeting lentiviral vectors to specific cell types in vivo. Proc. Natl. Acad. Sci. U.S.A. 103(31):11479-84
Suzue K, et al.
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Suzue K, Reinherz EL, Koyasu S
(2001) Critical role of NK but not NKT cells in acute rejection of parental bone marrow cells in F1 hybrid mice. Eur. J. Immunol. 31(11):3147-52
NK
Shinkai Y, et al.
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Shinkai Y, Koyasu S, Nakayama K, Murphy KM, Loh DY, Reinherz EL, Alt FW
(1993) Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. Science 259(5096):822-5
T And/Or B Cell Function
Schulz RJ, et al.
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Schulz RJ, Parkes A, Mizoguchi E, Bhan AK, Koyasu S
(1996) Development of CD4-CD8- alpha beta TCR+NK1.1+ T lymphocytes: thymic selection by self antigen. J. Immunol. 157(10):4379-89
Liu D, et al.
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Liu D, Hornsby PJ
(2007) Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: stress-induced premature senescence does not increase effect. Neoplasia 9(5):418-26
Iritani BM, et al.
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Iritani BM, Delrow J, Grandori C, Gomez I, Klacking M, Carlos LS, Eisenman RN
(2002) Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1. EMBO J. 21(18):4820-30
Horton RM, et al.
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Horton RM, Karachunski PI, Conti-Fine BM
(1995) PCR screening of transgenic RAG-2 "knockout" immunodeficient mice. BioTechniques 19(5):690-1
Gill N, et al.
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Gill N, Rosenthal KL, Ashkar AA
(2005) NK and NKT cell-independent contribution of interleukin-15 to innate protection against mucosal viral infection. J. Virol. 79(7):4470-8
NK
Dandekar AA, et al.
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Dandekar AA, Anghelina D, Perlman S
(2004) Bystander CD8 T-cell-mediated demyelination is interferon-gamma-dependent in a coronavirus model of multiple sclerosis. Am. J. Pathol. 164(2):363-9
T And/Or B Cell Function
Chen J, et al.
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Chen J, Shinkai Y, Young F, Alt FW
(1994) Probing immune functions in RAG-deficient mice. Curr. Opin. Immunol. 6(2):313-9
Chen J, et al.
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Chen J, Lansford R, Stewart V, Young F, Alt FW
(1993) RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development. Proc. Natl. Acad. Sci. U.S.A. 90(10):4528-32
Looney MR, et al.
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Looney MR, Su X, Van Ziffle JA, Lowell CA, Matthay MA
(2006) Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. J. Clin. Invest. 116(6):1615-23
Erlebacher A, et al.
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Erlebacher A, Lukens AK, Glimcher LH
(2002) Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo. Proc. Natl. Acad. Sci. U.S.A. 99(26):16940-5
Immunology