Rag2 - Model 601 Publications

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Shinkai Y, et al.
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Shinkai Y, Rathbun G, Lam KP, Oltz EM, Stewart V, Mendelsohn M, Charron J, Datta M, Young F, Stall AM
(1992) RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68(5):855-67
Krieglstein CF, et al.
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Krieglstein CF, Cerwinka WH, Sprague AG, Laroux FS, Grisham MB, Koteliansky VE, Senninger N, Granger DN, de Fougerolles AR
(2002) Collagen-binding integrin alpha1beta1 regulates intestinal inflammation in experimental colitis. J. Clin. Invest. 110(12):1773-82
Zúñiga-Pflücker JC, et al.
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Zúñiga-Pflücker JC, Jiang D, Schwartzberg PL, Lenardo MJ
(1994) Sublethal gamma-radiation induces differentiation of CD4-/CD8- into CD4+/CD8+ thymocytes without T cell receptor beta rearrangement in recombinase activation gene 2-/- mice. J. Exp. Med. 180(4):1517-21
Zhang K, et al.
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Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ
(2005) The unfolded protein response sensor IRE1α is required at 2 distinct steps in B cell lymphopoiesis J Clin Invest. 115(2):268-281
Yang L, et al.
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Yang L, Bailey L, Baltimore D, Wang P
(2006) Targeting lentiviral vectors to specific cell types in vivo. Proc. Natl. Acad. Sci. U.S.A. 103(31):11479-84
Suzue K, et al.
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Suzue K, Reinherz EL, Koyasu S
(2001) Critical role of NK but not NKT cells in acute rejection of parental bone marrow cells in F1 hybrid mice. Eur. J. Immunol. 31(11):3147-52
NK
Shinkai Y, et al.
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Shinkai Y, Koyasu S, Nakayama K, Murphy KM, Loh DY, Reinherz EL, Alt FW
(1993) Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. Science 259(5096):822-5
T And/Or B Cell Function
Schulz RJ, et al.
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Schulz RJ, Parkes A, Mizoguchi E, Bhan AK, Koyasu S
(1996) Development of CD4-CD8- alpha beta TCR+NK1.1+ T lymphocytes: thymic selection by self antigen. J. Immunol. 157(10):4379-89
Niki S, et al.
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Niki S, Oshikawa K, Mouri Y, Hirota F, Matsushima A, Yano M, Han H, Bando Y, Izumi K, Matsumoto M, Nakayama KI, Kuroda N, Matsumoto M
(2006) Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice. J. Clin. Invest. 116(5):1292-301
Lugo-Villarino G, et al.
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Lugo-Villarino G, Ito S, Klinman DM, Glimcher LH
(2005) The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 102(37):13248-53
Liu D, et al.
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Liu D, Hornsby PJ
(2007) Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: stress-induced premature senescence does not increase effect. Neoplasia 9(5):418-26
Iritani BM, et al.
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Iritani BM, Delrow J, Grandori C, Gomez I, Klacking M, Carlos LS, Eisenman RN
(2002) Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1. EMBO J. 21(18):4820-30
Horton RM, et al.
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Horton RM, Karachunski PI, Conti-Fine BM
(1995) PCR screening of transgenic RAG-2 "knockout" immunodeficient mice. BioTechniques 19(5):690-1
He H, et al.
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He H, Stone JR, Perkins DL
(2003) Analysis of differential immune responses induced by innate and adaptive immunity following transplantation. Immunology 109(2):185-96
Gill N, et al.
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Gill N, Rosenthal KL, Ashkar AA
(2005) NK and NKT cell-independent contribution of interleukin-15 to innate protection against mucosal viral infection. J. Virol. 79(7):4470-8
NK
Dandekar AA, et al.
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Dandekar AA, Anghelina D, Perlman S
(2004) Bystander CD8 T-cell-mediated demyelination is interferon-gamma-dependent in a coronavirus model of multiple sclerosis. Am. J. Pathol. 164(2):363-9
T And/Or B Cell Function
Chen J, et al.
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Chen J, Shinkai Y, Young F, Alt FW
(1994) Probing immune functions in RAG-deficient mice. Curr. Opin. Immunol. 6(2):313-9
Chen J, et al.
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Chen J, Lansford R, Stewart V, Young F, Alt FW
(1993) RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development. Proc. Natl. Acad. Sci. U.S.A. 90(10):4528-32
Looney MR, et al.
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Looney MR, Su X, Van Ziffle JA, Lowell CA, Matthay MA
(2006) Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. J. Clin. Invest. 116(6):1615-23
Pulmanausahakul R, et al.
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Pulmanausahakul R, Faber M, Morimoto K, Spitsin S, Weihe E, Hooper DC, Schnell MJ, Dietzschold B
(2001) Overexpression of cytochrome C by a recombinant rabies virus attenuates pathogenicity and enhances antiviral immunity. J. Virol. 75(22):10800-7
Virology