Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
Full Text |
| Stensballe A, et al. Mouse over for full list |
(2023) | Impaired Abcb1a function and red meat in a translational colitis mouse model induces inflammation and alters microbiota composition. | Front Med (Lausanne) 10:1200317 | Colitis, Immunology, Microbiome | ||
| Patton EA, et al. Mouse over for full list |
(2023) | Acute Administration of Ojeok-san Ameliorates Pain-like Behaviors in Pre-Clinical Models of Inflammatory Bowel Diseases. | Nutrients 15(7) | |||
| Singh G, et al. Mouse over for full list |
(2021) | Cage and maternal effects on the bacterial communities of the murine gut. | Sci Rep 11(1):9841 | |||
| Wu D, et al. Mouse over for full list |
(2019) | Dietary Depletion of Milk Exosomes and Their MicroRNA Cargos Elicits a Depletion of miR-200a-3p and Elevated Intestinal Inflammation and Chemokine (C-X-C Motif) Ligand 9 Expression in Mdr1a-/- Mice. | Curr Dev Nutr 3(12):nzz122 | |||
| Treuting PM, et al. Mouse over for full list |
(2017) | Authors' Response. | Vet Pathol 54(2):346-347 | |||
| Szabady RL, et al. Mouse over for full list |
(2018) | Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis. | J Clin Invest 128(9):4044-4056 | |||
| Leber A, et al. Mouse over for full list |
(2019) | Activation of NLRX1 by NX-13 Alleviates Inflammatory Bowel Disease through Immunometabolic Mechanisms in CD4 T Cells. | J Immunol 203(12):3407-3415 | |||
| Mir� L, et al. Mouse over for full list |
(2020) | Dietary Supplementation with Spray-Dried Porcine Plasma Attenuates Colon Inflammation in a Genetic Mouse Model of Inflammatory Bowel Disease. | Int J Mol Sci 21(18) | |||
| Bilsborough J, et al. Mouse over for full list |
(2020) | Select animal models of colitis and their value in predicting clinical efficacy of biological therapies in ulcerative colitis. | Expert Opin Drug Discov :1-11 | |||
| Leber A, et al. Mouse over for full list |
(2018) | Activation of LANCL2 by BT-11 Ameliorates IBD by Supporting Regulatory T Cell Stability Through Immunometabolic Mechanisms. | Inflamm. Bowel Dis. | |||
| Zhang YQ, et al. Mouse over for full list |
(2009) | Upregulation of activin signaling in experimental colitis. | Am. J. Physiol. Gastrointest. Liver Physiol. 297(4):G768-80 | |||
| Paul G, et al. Mouse over for full list |
(2012) | Interferon-? alters downstream signaling originating from epidermal growth factor receptor in intestinal epithelial cells: functional consequences for ion transport. | J. Biol. Chem. 287(3):2144-55 | |||
| McCole DF, et al. Mouse over for full list |
(2005) | Epidermal growth factor partially restores colonic ion transport responses in mouse models of chronic colitis. | Gastroenterology 129(2):591-608 | |||
| Resta-Lenert SC, et al. Mouse over for full list |
(2009) | Modulation of intestinal barrier properties by probiotics: role in reversing colitis. | Ann. N. Y. Acad. Sci. 1165:175-82 | |||
| Wilk JN, et al. Mouse over for full list |
(2005) | The mdr1a-/- mouse model of spontaneous colitis: a relevant and appropriate animal model to study inflammatory bowel disease. | Immunol. Res. 31(2):151-9 | |||
| Yau JL, et al. Mouse over for full list |
(2007) | The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice. | Neuropsychopharmacology 32(12):2520-9 | |||
| Bang B, et al. Mouse over for full list |
(2016) | Methods of Inducing Inflammatory Bowel Disease in Mice. | Curr Protoc Pharmacol 72:5.58.1-42 | |||
| Guner YS, et al. Mouse over for full list |
(2011) | P-glycoprotein induction by breast milk attenuates intestinal inflammation in experimental necrotizing enterocolitis. | Lab. Invest. 91(11):1668-79 | |||
| Ho GT, et al. Mouse over for full list |
(2017) | MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation. | Mucosal Immunol | |||
| Eisenbraun MD, et al. Mouse over for full list |
(2000) | Altered development of intestinal intraepithelial lymphocytes in P-glycoprotein-deficient mice. | Dev. Comp. Immunol. 24(8):783-95 | |||
| Barnett MP, et al. Mouse over for full list |
(2016) | Inoculation with enterococci does not affect colon inflammation in the multi-drug resistance 1a-deficient mouse model of IBD. | BMC Gastroenterol 16:31 | |||
| Lencioni KC, et al. Mouse over for full list |
(2008) | Murine norovirus: an intercurrent variable in a mouse model of bacteria-induced inflammatory bowel disease. | Comp. Med. 58(6):522-33 | |||
| Torrence AE, et al. Mouse over for full list |
(2008) | Serum biomarkers in a mouse model of bacterial-induced inflammatory bowel disease. | Inflamm. Bowel Dis. 14(4):480-90 | |||
| Fort MM, et al. Mouse over for full list |
(2005) | A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease. | J. Immunol. 174(10):6416-23 | |||
| Cooney JM, et al. Mouse over for full list |
(2016) | A combined omics approach to evaluate the effects of dietary curcumin on colon inflammation in the Mdr1a(-/-) mouse model of inflammatory bowel disease. | J. Nutr. Biochem. 27:181-92 | |||
| P�rez-Bosque A, et al. Mouse over for full list |
(2015) | Dietary intervention with serum-derived bovine immunoglobulins protects barrier function in a mouse model of colitis. | Am. J. Physiol. Gastrointest. Liver Physiol. 308(12):G1012-8 | |||
| Nones K, et al. Mouse over for full list |
(2009) | Multidrug resistance gene deficient (mdr1a-/-) mice have an altered caecal microbiota that precedes the onset of intestinal inflammation. | J. Appl. Microbiol. 107(2):557-66 | |||
| Maxwell JR, et al. Mouse over for full list |
(2015) | Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation. | Immunity 43(4):739-50 | |||
| Goralski KB, et al. Mouse over for full list |
(2003) | Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin. | Br. J. Pharmacol. 139(1):35-48 | |||
| P�rez-Bosque A, et al. Mouse over for full list |
(2016) | Oral Serum-Derived Bovine Immunoglobulin/Protein Isolate Has Immunomodulatory Effects on the Colon of Mice that Spontaneously Develop Colitis. | PLoS ONE 11(5):e0154823 | |||
| Dommels YE, et al. Mouse over for full list |
(2007) | Characterization of intestinal inflammation and identification of related gene expression changes in mdr1a(-/-) mice. | Genes Nutr 2(2):209-23 | |||
| Glymenaki M, et al. Mouse over for full list |
(2017) | Compositional Changes in the Gut Mucus Microbiota Precede the Onset of Colitis-Induced Inflammation. | Inflamm. Bowel Dis. 23(6):912-922 | |||
| Barnett MP, et al. Mouse over for full list |
(2013) | Modulation of colonic inflammation in Mdr1a(-/-) mice by green tea polyphenols and their effects on the colon transcriptome and proteome. | J. Nutr. Biochem. 24(10):1678-90 | |||
| Glymenaki M, et al. Mouse over for full list |
(2017) | Stability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation. | Sci Rep 7(1):8836 | |||
| Willis CR, et al. Mouse over for full list |
(2012) | Interleukin-7 receptor blockade suppresses adaptive and innate inflammatory responses in experimental colitis. | J Inflamm (Lond) 9(1):39 | |||
| Paturi G, et al. Mouse over for full list |
(2012) | Influence of dietary blueberry and broccoli on cecal microbiota activity and colon morphology in mdr1a(-/-) mice, a model of inflammatory bowel diseases. | Nutrition 28(3):324-30 | |||
| Bekker P, et al. Mouse over for full list |
(2015) | CCR9 Antagonists in the Treatment of Ulcerative Colitis. | Mediators Inflamm. 2015:628340 | |||
| Nones K, et al. Mouse over for full list |
(2009) | The effects of dietary curcumin and rutin on colonic inflammation and gene expression in multidrug resistance gene-deficient (mdr1a-/-) mice, a model of inflammatory bowel diseases. | Br. J. Nutr. 101(2):169-81 | |||
| Paik J, et al. Mouse over for full list |
(2013) | High-fat diet-induced obesity exacerbates inflammatory bowel disease in genetically susceptible Mdr1a-/- male mice. | J. Nutr. 143(8):1240-7 | |||
| Bhardwaj EK, et al. Mouse over for full list |
(2014) | Increased susceptibility to Trichuris muris infection and exacerbation of colitis in Mdr1a-/- mice. | World J. Gastroenterol. 20(7):1797-806 | |||
| Staley EM, et al. Mouse over for full list |
(2009) | Differential susceptibility of P-glycoprotein deficient mice to colitis induction by environmental insults. | Inflamm. Bowel Dis. 15(5):684-96 | |||
| Hennenberg EM, et al. Mouse over for full list |
(2017) | MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesis. | PLoS ONE 12(7):e0180834 | |||
| Haarberg KM, et al. Mouse over for full list |
(2015) | Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a(-/-) mice. | World J Gastrointest Pharmacol Ther 6(4):223-37 | |||
| Masunaga Y, et al. Mouse over for full list |
(2007) | Expression profiles of cytokines and chemokines in murine MDR1a-/- colitis. | Inflamm. Res. 56(11):439-46 | |||
| Tanner SM, et al. Mouse over for full list |
(2013) | Altered generation of induced regulatory T cells in the FVB.mdr1a-/- mouse model of colitis. | Mucosal Immunol 6(2):309-23 | |||
| Ey B, et al. Mouse over for full list |
(2013) | Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis. | J. Immunol. 190(11):5676-88 | |||
| Staley EM, et al. Mouse over for full list |
(2011) | Critical role for P-glycoprotein expression in hematopoietic cells in the FVB.Mdr1a(-/-) model of colitis. | J. Pediatr. Gastroenterol. Nutr. 53(6):666-73 | |||
| Collett A, et al. Mouse over for full list |
(2008) | Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(-/-) mice. | Inflamm. Bowel Dis. 14(5):620-31 | |||
| Stephens RH, et al. Mouse over for full list |
(2002) | Region-dependent modulation of intestinal permeability by drug efflux transporters: in vitro studies in mdr1a(-/-) mouse intestine. | J. Pharmacol. Exp. Ther. 303(3):1095-101 | |||
| Panwala CM, et al. Mouse over for full list |
(1998) | A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. | J. Immunol. 161(10):5733-44 | |||
| Banner KH, et al. Mouse over for full list |
(2004) | Macroscopic, microscopic and biochemical characterisation of spontaneous colitis in a transgenic mouse, deficient in the multiple drug resistance 1a gene. | Br. J. Pharmacol. 143(5):590-8 | |||
| Resta-Lenert S, et al. Mouse over for full list |
(2005) | Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice. | Am. J. Physiol. Gastrointest. Liver Physiol. 289(1):G153-62 | |||
| Schinkel AH, et al. Mouse over for full list |
(1994) | Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. | Cell 77(4):491-502 | |||
| Zhou S, et al. Mouse over for full list |
(2002) | Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. | Proc. Natl. Acad. Sci. U.S.A. 99(19):12339-44 | |||
| Schinkel AH, et al. Mouse over for full list |
(1996) | P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans | Proc Natl Acad Sci USA. 93:4001-5 | |||
| Schinkel AH, et al. Mouse over for full list |
(1996) | P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. | J Clin Invest. 97(11): 2517-2524 | |||
| Sparreboom A, et al. Mouse over for full list |
(1997) | Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. | Proc. Natl. Acad. Sci. U.S.A. 94(5):2031-5 | |||
| Neudeck BL, et al. Mouse over for full list |
(2004) | Intestinal P Glycoprotein Acts as a Natural Defense Mechanism against Listeria monocytogenes | Infect Immun. 72(7):3849-3854 | |||
| Maggio-Price L, et al. Mouse over for full list |
(2005) | Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia. | Am. J. Pathol. 166(6):1793-806 | |||
| Maggio-Price L, et al. Mouse over for full list |
(2002) | Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-deficient (mdr1a-/-) mice. | Am. J. Pathol. 160(2):739-51 | |||
| Cirrito JR, et al. Mouse over for full list |
(2005) | P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model. | J. Clin. Invest. 115(11):3285-90 | |||
| Neudeck BL, et al. Mouse over for full list |
(2004) | Intestinal P glycoprotein acts as a natural defense mechanism against Listeria monocytogenes. | Infect. Immun. 72(7):3849-54 | |||
| Miyama T, et al. Mouse over for full list |
(1998) | P-glycoprotein-mediated transport of itraconazole across the blood-brain barrier. | Antimicrob. Agents Chemother. 42(7):1738-44 |
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