Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
Full Text |
| Matikainen-Ankney BA, et al. Mouse over for full list Matikainen-Ankney BA, Kezunovic N, Menard C, Flanigan ME, Zhong Y, Russo SJ, Benson DL, Huntley GW |
(2018) | Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood. | J Neurosci 38(45):9700-9711 | |||
| Guevara CA, et al. Mouse over for full list Guevara CA, Matikainen-Ankney BA, Kezunovic N, LeClair K, Conway AP, Menard C, Flanigan ME, Pfau M, Russo SJ, Benson DL, Huntley GW |
(2020) | LRRK2 mutation alters behavioral, synaptic, and nonsynaptic adaptations to acute social stress. | J Neurophysiol 123(6):2382-2389 | |||
| Boecker CA, et al. Mouse over for full list Boecker CA, Goldsmith J, Dou D, Cajka GG, Holzbaur ELF |
(2021) | Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes. | Curr Biol 31(10):2140-2154.e6 | |||
| Sarkar S, et al. Mouse over for full list Sarkar S, Bardai F, Olsen AL, Lohr KM, Zhang YY, Feany MB |
(2021) | Oligomerization of Lrrk controls actin severing and α-synuclein neurotoxicity in vivo. | Mol Neurodegener 16(1):33 | |||
| Crown LM, et al. Mouse over for full list Crown LM, Bartlett MJ, Wiegand JL, Eby AJ, Monroe EJ, Gies K, Wohlford L, Fell MJ, Falk T, Cowen SL |
(2020) | Sleep Spindles and Fragmented Sleep as Prodromal Markers in a Preclinical Model of LRRK2-G2019S Parkinson's Disease. | Front Neurol 11:324 | |||
| Wang X, et al. Mouse over for full list Wang X, Negrou E, Maloney MT, Bondar VV, Andrews SV, Montalban M, Llapashtica C, Maciuca R, Nguyen H, Solanoy H, Arguello A, Przybyla L, Moerke NJ, Huntwork-Rodriguez S, Henry AG |
(2021) | Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10. | Sci Rep 11(1):12900 | |||
| De Miranda BR, et al. Mouse over for full list De Miranda BR, Castro SL, Rocha EM, Bodle CR, Johnson KE, Greenamyre JT |
(2021) | The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease. | Neurobiol Dis 153:105312 | |||
| Volta M, et al. Mouse over for full list Volta M, Beccano-Kelly DA, Paschall SA, Cataldi S, MacIsaac SE, Kuhlmann N, Kadgien CA, Tatarnikov I, Fox J, Khinda J, Mitchell E, Bergeron S, Melrose H, Farrer MJ, Milnerwood AJ |
(2017) | Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice. | Elife 6 | |||
| Matikainen-Ankney BA, et al. Mouse over for full list Matikainen-Ankney BA, Kezunovic N, Mesias RE, Tian Y, Williams FM, Huntley GW, Benson DL |
(2016) | Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S Mutation. | J. Neurosci. 36(27):7128-41 | Parkinson's |
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