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Filter publications by application: All Breast Cancer Colon Cancer Immuno-Oncology Immunology Infectious Disease Inflammation Lymphoma Metastases Oncology Pancreatic And Other Biliary Tract Cancers T And/Or B Cell Function Therapeutic Efficacy Evaluation Tuberculosis Vaccine Research
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Xu C, et al.
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Xu C, Marelli B, Qi J, Qin G, Yu H, Wang H, Jenkins MH, Lo KM, Lan Y
(2022) NHS-IL12 and bintrafusp alfa combination therapy enhances antitumor activity in preclinical cancer models. Transl Oncol 16:101322
Immuno-Oncology
Lemke-Miltner CD, et al.
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Lemke-Miltner CD, Blackwell SE, Yin C, Krug AE, Morris AJ, Krieg AM, Weiner GJ
(2020) Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization. J Immunol 204(5):1386-1394
Lymphoma, Immuno-Oncology
Kayraklioglu N, et al.
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Kayraklioglu N, Horuluoglu B, Elango M, Klinman DM
(2019) Critical Role of B Cells in Toll-Like Receptor 7-Mediated Protection against Listeria monocytogenes Infection. Infect Immun 87(12)
Immunology, T And/Or B Cell Function, Infectious Disease
Settem RP, et al.
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Settem RP, Honma K, Chinthamani S, Kawai T, Sharma A
(2021) B-Cell RANKL Contributes to Pathogen-Induced Alveolar Bone Loss in an Experimental Periodontitis Mouse Model. Front Physiol 12:722859
Immunology, Inflammation
Afkhami S, et al.
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Afkhami S, D'Agostino MR, Zhang A, Stacey HD, Marzok A, Kang A, Singh R, Bavananthasivam J, Ye G, Luo X, Wang F, Ang JC, Zganiacz A, Sankar U, Kazhdan N, Koenig JFE, Phelps A, Gameiro SF, Tang S, Jordana M, Wan Y, Mossman KL, Jeyanathan M, Gillgrass A, Medina MFC, Smaill F, Lichty BD, Miller MS, Xing Z
(2022) Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2. Cell 185(5):896-915.e19
Immunology, Vaccine Research
Keppler SJ, et al.
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Keppler SJ, Burbage M, Gasparrini F, Hartjes L, Aggarwal S, Massaad MJ, Geha RS, Bruckbauer A, Batista FD
(2018) The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses. Cell Rep 24(3):619-629
Immunology, T And/Or B Cell Function
Kurzejamska E, et al.
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Kurzejamska E, Sacharczuk M, Landázuri N, Kovtonyuk O, Lazarczyk M, Ananthaseshan S, Gaciong Z, Religa P
(2019) Effect of Chemokine (C-C Motif) Ligand 7 (CCL7) and Its Receptor (CCR2) Expression on Colorectal Cancer Behaviors. Int J Mol Sci 20(3)
Oncology, Colon Cancer, Metastases
Chen F, et al.
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Chen F, Wu W, Jin L, Millman A, Palma M, El-Naccache DW, Lothstein KE, Dong C, Edelblum KL, Gause WC
(2018) B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema. Cell Rep 25(10):2775-2783.e3
Butler NS, et al.
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Butler NS, Dandekar AA, Perlman S
(2007) Antiviral antibodies are necessary to prevent cytotoxic T-lymphocyte escape in mice infected with a coronavirus. J. Virol. 81(24):13291-8
Infectious Disease
Smith KM, et al.
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Smith KM, Rahman RS, Spencer LA
(2016) Humoral Immunity Provides Resident Intestinal Eosinophils Access to Luminal Antigen via Eosinophil-Expressed Low-Affinity Fcγ Receptors. J. Immunol. 197(9):3716-3724
Immunology
Mancini F, et al.
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Mancini F, Monaci E, Lofano G, Torre A, Bacconi M, Tavarini S, Sammicheli C, Arcidiacono L, Galletti B, Laera D, Pallaoro M, Tuscano G, Fontana MR, Bensi G, Grandi G, Rossi-Paccani S, Nuti S, Rappuoli R, De Gregorio E, Bagnoli F, Soldaini E, Bertholet S
(2016) One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A. PLoS ONE 11(1):e0147767
Vaccine Research
Lan Y, et al.
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Lan Y, Zhang D, Xu C, Hance KW, Marelli B, Qi J, Yu H, Qin G, Sircar A, Hernández VM, Jenkins MH, Fontana RE, Deshpande A, Locke G, Sabzevari H, Radvanyi L, Lo KM
(2018) Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-β. Sci Transl Med 10(424)
Oncology, Immuno-Oncology
Percopo CM, et al.
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Percopo CM, Dyer KD, Garcia-Crespo KE, Gabryszewski SJ, Shaffer AL, Domachowske JB, Rosenberg HF
(2014) B cells are not essential for Lactobacillus-mediated protection against lethal pneumovirus infection. J. Immunol. 192(11):5265-72
Immunology, Infectious Disease
Xu C, et al.
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Xu C, Zhang Y, Rolfe PA, Hernández VM, Guzman W, Kradjian G, Marelli B, Qin G, Qi J, Wang H, Yu H, Tighe R, Lo KM, English JM, Radvanyi L, Lan Y
(2017) Combination Therapy with NHS-muIL12 and Avelumab (anti-PD-L1) Enhances Antitumor Efficacy in Preclinical Cancer Models. Clin. Cancer Res. 23(19):5869-5880
Oncology, Therapeutic Efficacy Evaluation
Opata MM, et al.
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Opata MM, Hollifield ML, Lund FE, Randall TD, Dunn R, Garvy BA, Feola DJ
(2015) B Lymphocytes Are Required during the Early Priming of CD4+ T Cells for Clearance of Pneumocystis Infection in Mice. J. Immunol. 195(2):611-20
T And/Or B Cell Function, Infectious Disease
Hardy RR, et al.
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Hardy RR, Hayakawa K
(2015) Selection of natural autoreactive B cells. Clin. Exp. Rheumatol. 33(4 Suppl 92):S80-6
T And/Or B Cell Function
Monaci E, et al.
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Monaci E, Mancini F, Lofano G, Bacconi M, Tavarini S, Sammicheli C, Arcidiacono L, Giraldi M, Galletti B, Rossi Paccani S, Torre A, Fontana MR, Grandi G, de Gregorio E, Bensi G, Chiarot E, Nuti S, Bagnoli F, Soldaini E, Bertholet S
(2015) MF59- and Al(OH)3-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T Cells at Low Antibody Titers. Front Immunol 6:439
Vaccine Research
Gunderson AJ, et al.
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Gunderson AJ, Kaneda MM, Tsujikawa T, Nguyen AV, Affara NI, Ruffell B, Gorjestani S, Liudahl SM, Truitt M, Olson P, Kim G, Hanahan D, Tempero MA, Sheppard B, Irving B, Chang BY, Varner JA, Coussens LM
(2016) Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer. Cancer Discov 6(3):270-85
Oncology, Pancreatic And Other Biliary Tract Cancers, Immuno-Oncology
Khera AK, et al.
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Khera AK, Afkhami S, Lai R, Jeyanathan M, Zganiacz A, Mandur T, Hammill J, Damjanovic D, Xing Z
(2015) Role of B Cells in Mucosal Vaccine-Induced Protective CD8+ T Cell Immunity against Pulmonary Tuberculosis. J. Immunol. 195(6):2900-7
T And/Or B Cell Function, Tuberculosis, Vaccine Research
Shalapour S, et al.
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Shalapour S, Font-Burgada J, Di Caro G, Zhong Z, Sanchez-Lopez E, Dhar D, Willimsky G, Ammirante M, Strasner A, Hansel DE, Jamieson C, Kane CJ, Klatte T, Birner P, Kenner L, Karin M
(2015) Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy. Nature 521(7550):94-8
T And/Or B Cell Function, Oncology, Immuno-Oncology
Chen J, et al.
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Chen J, Trounstine M, Alt FW, Young F, Kurahara C, Loring JF, Huszar D
(1993) Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus. Int. Immunol. 5(6):647-56
Vargas ME, et al.
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Vargas ME, Watanabe J, Singh SJ, Robinson WH, Barres BA
(2010) Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury. Proc. Natl. Acad. Sci. U.S.A. 107(26):11993-8
Teijaro JR, et al.
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Teijaro JR, Verhoeven D, Page CA, Turner D, Farber DL
(2010) Memory CD4 T cells direct protective responses to influenza virus in the lungs through helper-independent mechanisms. J. Virol. 84(18):9217-26
T And/Or B Cell Function
Schioppa T, et al.
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Schioppa T, Moore R, Thompson RG, Rosser EC, Kulbe H, Nedospasov S, Mauri C, Coussens LM, Balkwill FR
(2011) B regulatory cells and the tumor-promoting actions of TNF-α during squamous carcinogenesis. Proc. Natl. Acad. Sci. U.S.A. 108(26):10662-7
Rios D, et al.
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Rios D, Wood MB, Li J, Chassaing B, Gewirtz AT, Williams IR
(2016) Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria. Mucosal Immunol 9(4):907-16
Park JM, et al.
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Park JM, Terabe M, Steel JC, Forni G, Sakai Y, Morris JC, Berzofsky JA
(2008) Therapy of advanced established murine breast cancer with a recombinant adenoviral ErbB-2/neu vaccine. Cancer Res. 68(6):1979-87
Breast Cancer
Opata MM, et al.
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Opata MM, Ye Z, Hollifield M, Garvy BA
(2013) B cell production of tumor necrosis factor in response to Pneumocystis murina infection in mice. Infect. Immun. 81(11):4252-60
T And/Or B Cell Function
Moore ML, et al.
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Moore ML, McKissic EL, Brown CC, Wilkinson JE, Spindler KR
(2004) Fatal disseminated mouse adenovirus type 1 infection in mice lacking B cells or Bruton's tyrosine kinase. J. Virol. 78(11):5584-90
T And/Or B Cell Function
Miles SA, et al.
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Miles SA, Conrad SM, Alves RG, Jeronimo SMB, Mosser DM
(2006) A role for IgG immune complexes during infection with the intracellular pathogen Leishmania J Exp Med. 201(5):747-54
Matthews AE, et al.
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Matthews AE, Weiss SR, Shlomchik MJ, Hannum LG, Gombold JL, Paterson Y
(2001) Antibody is required for clearance of infectious murine hepatitis virus A59 from the central nervous system, but not the liver. J. Immunol. 167(9):5254-63
Liu Q, et al.
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Liu Q, Kreider T, Bowdridge S, Liu Z, Song Y, Gaydo AG, Urban JF, Gause WC
(2010) B cells have distinct roles in host protection against different nematode parasites. J. Immunol. 184(9):5213-23
T And/Or B Cell Function
Li Z, et al.
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Li Z, Gabbard JD, Johnson S, Dlugolenski D, Phan S, Tompkins SM, He B
(2015) Efficacy of a parainfluenza virus 5 (PIV5)-based H7N9 vaccine in mice and guinea pigs: antibody titer towards HA was not a good indicator for protection. PLoS ONE 10(3):e0120355
Keppler SJ, et al.
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Keppler SJ, Gasparrini F, Burbage M, Aggarwal S, Frederico B, Geha RS, Way M, Bruckbauer A, Batista FD
(2015) Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells. Immunity 43(4):660-73
T And/Or B Cell Function
Jensen KM, et al.
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Jensen KM, Melchjorsen J, Dagnaes-Hansen F, Sørensen UB, Laursen RR, Østergaard L, Søgaard OS, Tolstrup M
(2012) Timing of Toll-like receptor 9 agonist administration in pneumococcal vaccination impacts both humoral and cellular immune responses as well as nasopharyngeal colonization in mice. Infect. Immun. 80(5):1744-52
Vaccine Research
Headley MB, et al.
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Headley MB, Zhou B, Shih WX, Aye T, Comeau MR, Ziegler SF
(2009) TSLP conditions the lung immune environment for the generation of pathogenic innate and antigen-specific adaptive immune responses. J. Immunol. 182(3):1641-7
Goenka R, et al.
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Goenka R, Parent MA, Elzer PH, Baldwin CL
(2011) B cell-deficient mice display markedly enhanced resistance to the intracellular bacterium Brucella abortus. J. Infect. Dis. 203(8):1136-46
T And/Or B Cell Function
Glatman Zaretsky A, et al.
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Glatman Zaretsky A, Taylor JJ, King IL, Marshall FA, Mohrs M, Pearce EJ
(2009) T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J. Exp. Med. 206(5):991-9
El-Malky MA, et al.
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El-Malky MA, Maruyama H, Al-Harthi SA, El-Beshbishi SN, Ohta N
(2013) The role of B-cells in immunity against adult Strongyloides venezuelensis. Parasit Vectors 6:148
T And/Or B Cell Function
Deak E, et al.
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Deak E, Jayakumar A, Cho KW, Goldsmith-Pestana K, Dondji B, Lambris JD, McMahon-Pratt D
(2010) Murine visceral leishmaniasis: IgM and polyclonal B-cell activation lead to disease exacerbation. Eur. J. Immunol. 40(5):1355-68
T And/Or B Cell Function
De Pascalis R, et al.
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De Pascalis R, Mittereder L, Chou AY, Kennett NJ, Elkins KL
(2015) Francisella tularensis Vaccines Elicit Concurrent Protective T- and B-Cell Immune Responses in BALB/cByJ Mice. PLoS ONE 10(5):e0126570
T And/Or B Cell Function
Delpy L, et al.
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Delpy L, Sirac C, Magnoux E, Duchez S, Cogné M
(2004) RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon. Proc. Natl. Acad. Sci. U.S.A. 101(19):7375-80
Christensen JP, et al.
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Christensen JP, Kauffmann SØ, Thomsen AR
(2003) Deficient CD4+ T Cell Priming and Regression of CD8+ T Cell Functionality in Virus-Infected Mice Lacking a Normal B Cell Compartment J Immunol. 171(9):4733-41
T And/Or B Cell Function
Chimen M, et al.
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Chimen M, McGettrick HM, Apta B, Kuravi SJ, Yates CM, Kennedy A, Odedra A, Alassiri M, Harrison M, Martin A, Barone F, Nayar S, Hitchcock JR, Cunningham AF, Raza K, Filer A, Copland DA, Dick AD, Robinson J, Kalia N, Walker LS, Buckley CD, Nash GB, Narendran P, Rainger GE
(2015) Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease. Nat. Med. 21(5):467-75
T And/Or B Cell Function
Blutt SE, et al.
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Blutt SE, Warfield KL, Estes MK, Conner ME
(2008) Differential requirements for T cells in viruslike particle- and rotavirus-induced protective immunity. J. Virol. 82(6):3135-8
T And/Or B Cell Function
Baiu DC, et al.
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Baiu DC, Sandor M, Hart M
(2010) CD4+ T cells sensitized by vascular smooth muscle induce vasculitis, and interferon gamma is critical for the initiation of vascular pathology. Am. J. Pathol. 177(6):3215-23
T And/Or B Cell Function
Wyatt LS, et al.
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Wyatt LS, Earl PL, Eller LA, Moss B
(2004) Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge. Proc. Natl. Acad. Sci. U.S.A. 101(13):4590-5
Vaccine Research
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