huNOG-EXL SA (Standard Access) Publications

huNOG-EXL SA (Standard Access) Model Page

Filter publications by application: All Diabetes (Type 1) Humanized Hypersensitivities Immuno-Oncology Immunology Immunotherapy Induced Pluripotent Stem Cells (iPSCs) Infectious Disease Inflammation Leukemia Lung Cancer Melanoma Metastases Oncology Patient Derived Xenograft (PDX) Stem Cells/Regenerative Medicine/Tissue Engineering Therapeutic Efficacy Evaluation
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Ghoneim MA, et al.
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Ghoneim MA, Gabr MM, Refaie AF, El-Halawani SM, Al-Issawi MM, Elbassiouny BL, Kader MAAE, Ismail AM, Zidan MF, Karras MS, Magar RW, Khater SM, Ashamallah SA, Zakaria MM, Kloc M
(2022) Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice. Stem Cell Res Ther 13(1):350
Diabetes (Type 1), Stem Cells/Regenerative Medicine/Tissue Engineering, Induced Pluripotent Stem Cells (iPSCs)
Nalle S, et al.
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Nalle S, Lam H, Leung L, et al
(2021) 875 AL009, a fusion protein and multi-Siglec inhibitor, repolarizes suppressive myeloid cells and potentiates anti-cancer effects Journal for ImmunoTherapy of Cancer 2021;9
Oncology, Immunotherapy, Therapeutic Efficacy Evaluation, Humanized
Lea S, et al.
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Lea S, Chen C, Hartley G, et al.
(2021) 763 Intratumoral delivery of high potency STING agonists modulates the immunosuppressive myeloid compartment and induces curative responses in checkpoint-refractory glioblastoma models Journal for ImmunoTherapy of Cancer 2021;9
Oncology, Immunotherapy, Therapeutic Efficacy Evaluation, Humanized
Jonathan Nakashima; Jantzen Sperry; Christophe Pedros; Bianca Carapia; Deborah Yan; Giovanni Rivera; Aliakbar Shahsafaei; Noah Federman; Arun Singh; Fritz C. Eilber; Brian Datnow.
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Jonathan Nakashima; Jantzen Sperry; Christophe Pedros; Bianca Carapia; Deborah Yan; Giovanni Rivera; Aliakbar Shahsafaei; Noah Federman; Arun Singh; Fritz C. Eilber; Brian Datnow.
(2022) Development of Bioluminescent PDX Models to Study Metastasis and Evaluate Therapeutic Interventions Poster presented at AACR Annual Meeting, Apr 2022
Oncology, Metastases, Immuno-Oncology, Humanized
Justin A. Kenkel, et al.
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Justin A. Kenkel, Po Y. Ho, Karla A. Henning, Cindy L. Kreder, Jess L. Nolin, Sameera Kongara, Steven J. Chapin, Amreen Husain, Marcin Kowanetz, Edgar G. Engleman, Michael N. Alonso, David Dornan, Shelley E. Ackerman
(2022) Dectin-2 agonist antibodies reprogram tumor-associated macrophages to drive anti-tumor immunity Poster presented at AACR Annual Meeting, Apr 2022.
Oncology, Immuno-Oncology, Humanized
Kumar S, et al.
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Kumar S, Ghosh S, Sharma G, Wang Z, Kehry MR, Marino MH, Neben TY, Lu S, Luo S, Roberts S, Ramaswamy S, Danaee H, Jenkins D
(2021) Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal models. MAbs 13(1):1954136
Vendramin R, et al.
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Vendramin R, Katopodi V, Cinque S, Konnova A, Knezevic Z, Adnane S, Verheyden Y, Karras P, Demesmaeker E, Bosisio FM, Kucera L, Rozman J, Gladwyn-Ng I, Rizzotto L, Dassi E, Millevoi S, Bechter O, Marine JC, Leucci E
(2021) Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma. J Exp Med 218(9)
Oncology, Melanoma, Patient Derived Xenograft (PDX), Therapeutic Efficacy Evaluation
Janell R. Richardson, et al.
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Janell R. Richardson, Megan MacBride, Esther Andino, Marla Wilwol, SueEllen Bethmann, Taylor Knapp, Emily Shako, Paul Volden.
(2021) Defining Variation within a Next Gen Humanized Immune System Mouse Model of Human Lung Cancer in the Context of a Checkpoint Inhibitor Efficacy Study AACR 2021 poster
Lung Cancer, Immuno-Oncology, Humanized
Dai G, et al.
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Dai G, Wanek A, Eddens T, Volden P, Kolls JK
(2021) Toward a humanized mouse model of Pneumocystis pneumonia. JCI Insight 6(2)
Infectious Disease
Ito R, et al.
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Ito R, Katano I, Otsuka I, Takahashi T, Suemizu H, Ito M, Simons PJ
(2020) Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice. Int Immunol
Immunology
Maser IP, et al.
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Maser IP, Hoves S, Bayer C, Heidkamp G, Nimmerjahn F, Eckmann J, Ries CH
(2020) The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models. Front Immunol 11:2082
Ghosh S, et al.
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Ghosh S, Sharma G, Travers J, Kumar S, Choi J, Jun HT, Kehry M, Ramaswamy S, Jenkins D
(2019) TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade and . Mol. Cancer Ther. 18(3):632-641
Wang Z, et al.
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Wang Z, Sun K, Xiao Y, Feng B, Mikule K, Ma X, Feng N, Vellano CP, Federico L, Marszalek JR, Mills GB, Hanke J, Ramaswamy S, Wang J
(2019) Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models. Sci Rep 9(1):1853
Perdomo-Celis F, et al.
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Perdomo-Celis F, Medina-Moreno S, Davis H, Bryant J, Zapata JC
(2019) HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice. Pathogens 8(1)
Ito R, et al.
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Ito R, Maruoka S, Soda K, Katano I, Kawai K, Yagoto M, Hanazawa A, Takahashi T, Ogura T, Goto M, Takahashi R, Toyoshima S, Okayama Y, Izuhara K, Gon Y, Hashimoto S, Ito M, Nunomura S
(2018) A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis. JCI Insight 3(21)
Ito R, et al.
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Ito R, Nagai D, Igo N, Okuda Y, Sekine K, Ichimura E, Katano I, Mizushima T, Goto M, Ohnishi Y, Ito M, Okamoto K
(2017) A novel in vivo model for predicting myelotoxicity of chemotherapeutic agents using IL-3/GM-CSF transgenic humanized mice. Toxicol. Lett. 281:152-157
Ito R, et al.
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Ito R, Takahashi T, Katano I, Kawai K, Kamisako T, Ogura T, Ida-Tanaka M, Suemizu H, Nunomura S, Ra C, Mori A, Aiso S, Ito M
(2013) Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice. J. Immunol. 191(6):2890-9
Immunology, Inflammation, Hypersensitivities, Humanized
Fukuchi Y, et al.
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Fukuchi Y, Miyakawa Y, Kobayashi K, Kuramochi T, Shimamura K, Tamaoki N, Nomura T, Ueyama Y, Ito M
(1998) Cytokine dependent growth of human TF-1 leukemic cell line in human GM-CSF and IL-3 producing transgenic SCID mice. Leuk. Res. 22(9):837-43
Oncology, Leukemia, Humanized
Mamoru Ito, et al.
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Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi, Kazutomo Suzue, Mariko Kawahata, Kyoji Hioki, Yoshito Ueyama, Yoshio Koyanagi, Kazuo Sugamura, Kohichiro Tsuji, Toshio Heike, Tatsutoshi Nakahata
(2002) NOD/SCID/γ nullc mouse: an excellent recipient mouse model for engraftment of human cells Blood 2002 100:3175-3182
Humanized
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