Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
Full Text |
| Yan C, et al. Mouse over for full list |
(2023) | Generation of Orthotopic Patient-Derived Xenografts in Humanized Mice for Evaluation of Emerging Targeted Therapies and Immunotherapy Combinations for Melanoma. | Cancers (Basel) 15(14) | Oncology, Immunotherapy, Melanoma, Patient Derived Xenograft (PDX), Immuno-Oncology | ||
| Amanda Chin, et al. Mouse over for full list |
(2023) | Targeting Myeloid-Derived Suppressor Cells with Actinium-225 Lintuzumab, a CD33 Antibody Radioconjugate to Enhance Antitumor Immunity | AACR 2023 poster | Oncology, Immuno-Oncology | ||
| Chen C, et al. Mouse over for full list |
(2022) | Intracavity generation of glioma stem cell-specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy. | Sci Transl Med 14(656):eabn1128 | |||
| Cao B, et al. Mouse over for full list |
(2022) | Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer. | Nat Commun 13(1):6203 | |||
| Yang J, et al. Mouse over for full list |
(2022) | AL008 Enhances Myeloid Antitumor Function by Inhibiting SIRP? Signaling and Activating Fc Receptors. | J Immunol | |||
| Ghoneim MA, et al. Mouse over for full list |
(2022) | Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice. | Stem Cell Res Ther 13(1):350 | Diabetes (Type 1), Stem Cells/Regenerative Medicine/Tissue Engineering, Induced Pluripotent Stem Cells (iPSCs) | ||
| Nalle S, et al. Mouse over for full list |
(2021) | 875?AL009, a fusion protein and multi-Siglec inhibitor, repolarizes suppressive myeloid cells and potentiates anti-cancer effects | Journal for ImmunoTherapy of Cancer 2021;9 | Oncology, Immunotherapy, Therapeutic Efficacy Evaluation, Humanized | ||
| Lea S, et al. Mouse over for full list |
(2021) | 763?Intratumoral delivery of high potency STING agonists modulates the immunosuppressive myeloid compartment and induces curative responses in checkpoint-refractory glioblastoma models | Journal for ImmunoTherapy of Cancer 2021;9 | Oncology, Immunotherapy, Therapeutic Efficacy Evaluation, Humanized | ||
| Jonathan Nakashima; Jantzen Sperry; Christophe Pedros; Bianca Carapia; Deborah Yan; Giovanni Rivera; Aliakbar Shahsafaei; Noah Federman; Arun Singh; Fritz C. Eilber; Brian Datnow. Mouse over for full list |
(2022) | Development of Bioluminescent PDX Models to Study Metastasis and Evaluate Therapeutic Interventions | Poster presented at AACR Annual Meeting, Apr 2022 | Oncology, Metastases, Immuno-Oncology, Humanized | ||
| Justin A. Kenkel, et al. Mouse over for full list |
(2022) | Dectin-2 agonist antibodies reprogram tumor-associated macrophages to drive anti-tumor immunity | Poster presented at AACR Annual Meeting, Apr 2022. | Oncology, Immuno-Oncology, Humanized | ||
| Kumar S, et al. Mouse over for full list |
(2021) | Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal models. | MAbs 13(1):1954136 | Immunology | ||
| Vendramin R, et al. Mouse over for full list |
(2021) | Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma. | J Exp Med 218(9) | Oncology, Melanoma, Patient Derived Xenograft (PDX), Therapeutic Efficacy Evaluation | ||
| Janell R. Richardson, et al. Mouse over for full list |
(2021) | Defining Variation within a Next Gen Humanized Immune System Mouse Model of Human Lung Cancer in the Context of a Checkpoint Inhibitor Efficacy Study | AACR 2021 poster | Lung Cancer, Immuno-Oncology, Humanized | ||
| Dai G, et al. Mouse over for full list |
(2021) | Toward a humanized mouse model of Pneumocystis pneumonia. | JCI Insight 6(2) | Infectious Disease | ||
| Ito R, et al. Mouse over for full list |
(2020) | Bovine ?-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice. | Int Immunol | Immunology | ||
| Maser IP, et al. Mouse over for full list |
(2020) | The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models. | Front Immunol 11:2082 | |||
| Ghosh S, et al. Mouse over for full list |
(2019) | TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade and . | Mol. Cancer Ther. 18(3):632-641 | |||
| Wang Z, et al. Mouse over for full list |
(2019) | Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models. | Sci Rep 9(1):1853 | |||
| Perdomo-Celis F, et al. Mouse over for full list |
(2019) | HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice. | Pathogens 8(1) | |||
| Ito R, et al. Mouse over for full list |
(2018) | A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis. | JCI Insight 3(21) | |||
| Ito R, et al. Mouse over for full list |
(2017) | A novel in vivo model for predicting myelotoxicity of chemotherapeutic agents using IL-3/GM-CSF transgenic humanized mice. | Toxicol. Lett. 281:152-157 | |||
| Ito R, et al. Mouse over for full list |
(2013) | Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice. | J. Immunol. 191(6):2890-9 | Immunology, Inflammation, Hypersensitivities, Humanized | ||
| Fukuchi Y, et al. Mouse over for full list |
(1998) | Cytokine dependent growth of human TF-1 leukemic cell line in human GM-CSF and IL-3 producing transgenic SCID mice. | Leuk. Res. 22(9):837-43 | Oncology, Leukemia, Humanized | ||
| Mamoru Ito, et al. Mouse over for full list |
(2002) | NOD/SCID/? nullc mouse: an excellent recipient mouse model for engraftment of human cells | Blood 2002 100:3175-3182 | Humanized |
Welcome! Tell us a little about yourself