Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
Full Text |
| Huarte E, et al. Mouse over for full list |
(2021) | Ruxolitinib, a JAK1/JAK2 selective inhibitor, ameliorates acute and chronic steroid-refractory GvHD mouse models. | Immunotherapy | NK, Transplantation Research And Graft Versus Host Disease (GVHD) | ||
| Jens Pahl, et al. Mouse over for full list |
(2021) | AFM24 is a novel, highly potent, tetravalent bispecific EGFR/CD16A-targeting Innate Cell Engager (ICE®) designed for the treatment of EGFR-positive malignancies | AACR 2021 poster | NK, Breast Cancer, Immuno-Oncology | ||
| Kevin R. Kipp, et al. Mouse over for full list |
(2021) | BNZ-2, a dual specific IL15/IL21 inhibitor, rescues humanized NOG-IL15 transgenic mice from intestinal acute graft vs host disease without disrupting NK and CD8 T cell engraftment | AACR 2021 poster | NK, Transplantation Research And Graft Versus Host Disease (GVHD), Immuno-Oncology | ||
| C. Rudulier, et al. Mouse over for full list |
(2020) | In vivo Model Development for Genome-Edited T Cell Therapeutics | ASGCT Poster | NK, T And/Or B Cell Function, Safety Assessment, Immuno-Oncology | ||
| Paul Volden, et al. Mouse over for full list |
(2018) | Cytokine-transgenic NOG mice engrafted with human peripheral blood cells support natural killer cell expansion | American Association for Cancer Research 2018 Conference | Humanization, Random integration transgene |
Immunology, NK, Antibody-Dependent-Cellular Cytotoxicity (ADCC), Transplantation Research And Graft Versus Host Disease (GVHD), Immunotherapy, Immuno-Oncology, Gene/Cell therapy | |
| Katano I, et al. Mouse over for full list |
(2017) | Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse. | Sci Rep 7(1):17230 | Humanization, Random integration transgene |
Immunology, NK, Antibody-Dependent-Cellular Cytotoxicity (ADCC), Oncology, Gastric Cancer, Gene/Cell therapy, Humanized | |
| Ikumi Katano, et al. Mouse over for full list |
(2016) | Human interleukin-15 transgenic NOG mice support the long-term maintenance of human mature NK cells from peripheral blood | Ikumi Katano, Takeshi Takahashi, Ryoji Ito, Asami Hanazawa, Mamoru Ito. (2016). Central Institute for Experimental Animals, Kawasaki, Japan. |
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