hIL-15 NOG Publications

hIL-15 NOG Model Page

Filter publications by application: All Antibody-Dependent-Cellular Cytotoxicity (ADCC) Breast Cancer Gastric Cancer Gene/Cell therapy Humanized Immuno-Oncology Immunology Immunotherapy NK Oncology Safety Assessment T And/Or B Cell Function Transplantation Research And Graft Versus Host Disease (GVHD)
Filter publications by model type: All Humanization Random integration transgene

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Huarte E, et al.
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Huarte E, Peel M, Juvekar A, Dubé P, Sarah S, Stephens L, Stewart B, Long B, Czerniak P, Oliver J, Smith P
(2021) Ruxolitinib, a JAK1/JAK2 selective inhibitor, ameliorates acute and chronic steroid-refractory GvHD mouse models. Immunotherapy
NK, Transplantation Research And Graft Versus Host Disease (GVHD)
Jens Pahl, et al.
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Jens Pahl, Gabriele Hintzen, Uwe Reusch, Torsten Haneke, Christian Breunig, Sheena Pinto, Cassandra Choe-Juliak, Andreas Harstrick, Wolfgang Fischer, Arndt Schottelius, Joachim Koch, Erich Rajkovic
(2021) AFM24 is a novel, highly potent, tetravalent bispecific EGFR/CD16A-targeting Innate Cell Engager (ICE®) designed for the treatment of EGFR-positive malignancies AACR 2021 poster
NK, Breast Cancer, Immuno-Oncology
Kevin R. Kipp, et al.
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Kevin R. Kipp, Nick Doerr, Laith Q. Al-Mawsawi, Woo Jae Kim, Adrian J. Giovannone, Nazli Azimi
(2021) BNZ-2, a dual specific IL15/IL21 inhibitor, rescues humanized NOG-IL15 transgenic mice from intestinal acute graft vs host disease without disrupting NK and CD8 T cell engraftment AACR 2021 poster
NK, Transplantation Research And Graft Versus Host Disease (GVHD), Immuno-Oncology
C. Rudulier, et al.
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C. Rudulier, V. Ragothaman, E. McMichael, U. Jetley, M. Borah, N. Ganci, I. Balwani, A. Frain, P. Venkatesan, Y. Miki, J. Jones, T. Luster, M. Keenan, T. Martinez, B. Schultes, Y. Zhang
(2020) In vivo Model Development for Genome-Edited T Cell Therapeutics ASGCT Poster
NK, T And/Or B Cell Function, Safety Assessment, Immuno-Oncology
Paul Volden, et al.
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Paul Volden, Azusa Tanaka, Dimitri Gimnopoulos, Magdalena Paterka, Iduna Fichtner
(2018) Cytokine-transgenic NOG mice engrafted with human peripheral blood cells support natural killer cell expansion   American Association for Cancer Research 2018 Conference
Humanization, Random integration transgene
Immunology, NK, Antibody-Dependent-Cellular Cytotoxicity (ADCC), Transplantation Research And Graft Versus Host Disease (GVHD), Immunotherapy, Immuno-Oncology, Gene/Cell therapy
Katano I, et al.
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Katano I, Nishime C, Ito R, Kamisako T, Mizusawa T, Ka Y, Ogura T, Suemizu H, Kawakami Y, Ito M, Takahashi T
(2017) Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse. Sci Rep 7(1):17230
Humanization, Random integration transgene
Immunology, NK, Antibody-Dependent-Cellular Cytotoxicity (ADCC), Oncology, Gastric Cancer, Gene/Cell therapy, Humanized
Ikumi Katano, et al.
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Ikumi Katano, Takeshi Takahashi, Ryoji Ito, Asami Hanazawa, Mamoru Ito.
(2016) Human interleukin-15 transgenic NOG mice support the long-term maintenance of human mature NK cells from peripheral blood Ikumi Katano, Takeshi Takahashi, Ryoji Ito, Asami Hanazawa, Mamoru Ito. (2016). Central Institute for Experimental Animals, Kawasaki, Japan.
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