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(Date) |
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| Abdurrachim D, et al. Mouse over for full list |
(2019) | A new hyperpolarized C ketone body probe reveals an increase in acetoacetate utilization in the diabetic rat heart. | Sci Rep 9(1):5532 | Cardiovascular | ||
| Špaček T, et al. Mouse over for full list |
(2017) | Nkx6.1 decline accompanies mitochondrial DNA reduction but subtle nucleoid size decrease in pancreatic islet β-cells of diabetic Goto Kakizaki rats. | Sci Rep 7(1):15674 | Diabetes (Type 2) | ||
| Gavin TP, et al. Mouse over for full list |
(2011) | Duodenal-jejunal bypass surgery does not increase skeletal muscle insulin signal transduction or glucose disposal in Goto-Kakizaki type 2 diabetic rats. | Obes Surg 21(2):231-7 | Diabetes (Type 2) | ||
| Cahová M, et al. Mouse over for full list |
(2017) | Lipasin/betatrophin is differentially expressed in liver and white adipose tissue without association with insulin resistance in Wistar and Goto-Kakizaki rats. | Physiol Res 66(2):273-281 | Diabetes (Type 2) | ||
| Salinari S, et al. Mouse over for full list |
(2014) | Duodenal-jejunal bypass and jejunectomy improve insulin sensitivity in Goto-Kakizaki diabetic rats without changes in incretins or insulin secretion. | Diabetes 63(3):1069-78 | Diabetes (Type 2) | ||
| Grong E, et al. Mouse over for full list |
(2016) | Sleeve gastrectomy, but not duodenojejunostomy, preserves total beta-cell mass in Goto-Kakizaki rats evaluated by three-dimensional optical projection tomography. | Surg Endosc 30(2):532-42 | Diabetes (Type 2) | ||
| Rothschild PR, et al. Mouse over for full list |
(2017) | ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy. | Sci Rep 7(1):8834 | Diabetes (Type 2) | ||
| Gao W, et al. Mouse over for full list |
(2011) | Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats. | J Pharmacokinet Pharmacodyn 38(1):143-62 | Diabetes (Type 2) | ||
| Nie J, et al. Mouse over for full list |
(2011) | Mechanistic population modeling of diabetes disease progression in Goto-Kakizaki rat muscle. | Biopharm Drug Dispos 32(1):50-63 | |||
| Kelly-Cobbs A, et al. Mouse over for full list |
(2011) | Pressure-independent cerebrovascular remodelling and changes in myogenic reactivity in diabetic Goto-Kakizaki rat in response to glycaemic control. | Acta Physiol (Oxf) 203(1):245-51 | Diabetes (Type 2) | ||
| Li W, et al. Mouse over for full list |
(2013) | Comparative analysis of the neurovascular injury and functional outcomes in experimental stroke models in diabetic Goto-Kakizaki rats. | Brain Res. 1541:106-14 | |||
| Ghanaat-Pour H, et al. Mouse over for full list |
(2007) | Global expression profiling of glucose-regulated genes in pancreatic islets of spontaneously diabetic Goto-Kakizaki rats. | J. Mol. Endocrinol. 39(2):135-50 | |||
| Peschke E, et al. Mouse over for full list |
(2010) | Long-term enteral administration of melatonin reduces plasma insulin and increases expression of pineal insulin receptors in both Wistar and type 2-diabetic Goto-Kakizaki rats. | J. Pineal Res. 49(4):373-81 | |||
| Almon RR, et al. Mouse over for full list |
(2009) | Gene expression analysis of hepatic roles in cause and development of diabetes in Goto-Kakizaki rats. | J. Endocrinol. 200(3):331-46 | |||
| Rose T, et al. Mouse over for full list |
(2007) | Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats. | J. Gen. Physiol. 129(6):493-508 | |||
| Frese T, et al. Mouse over for full list |
(2009) | Pineal melatonin synthesis is decreased in type 2 diabetic Goto-Kakizaki rats. | Life Sci. 85(13-14):526-33 | |||
| Olearczyk JJ, et al. Mouse over for full list |
(2009) | Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. | Clin. Sci. 116(1):61-70 | |||
| Kindel TL, et al. Mouse over for full list |
(2009) | Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism. | J. Gastrointest. Surg. 13(10):1762-72 | |||
| Patriti A, et al. Mouse over for full list |
(2007) | How the hindgut can cure type 2 diabetes. Ileal transposition improves glucose metabolism and beta-cell function in Goto-kakizaki rats through an enhanced Proglucagon gene expression and L-cell number. | Surgery 142(1):74-85 | |||
| Peschke E, et al. Mouse over for full list |
(2006) | Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status. | J. Pineal Res. 40(2):135-43 | |||
| Pacheco D, et al. Mouse over for full list |
(2007) | The effects of duodenal-jejunal exclusion on hormonal regulation of glucose metabolism in Goto-Kakizaki rats. | Am. J. Surg. 194(2):221-4 | |||
| de Luis D, et al. Mouse over for full list |
(2012) | Effects of duodenal-jejunal exclusion on beta cell function and hormonal regulation in Goto-Kakizaki rats. | Am. J. Surg. 204(2):242-7 | |||
| Copp SW, et al. Mouse over for full list |
(2010) | Effects of type II diabetes on exercising skeletal muscle blood flow in the rat. | J. Appl. Physiol. 109(5):1347-53 | |||
| Xue B, et al. Mouse over for full list |
(2011) | Adipose tissue deficiency and chronic inflammation in diabetic Goto-Kakizaki rats. | PLoS ONE 6(2):e17386 | |||
| Whittington HJ, et al. Mouse over for full list |
(2013) | Cardioprotection in the aging, diabetic heart: the loss of protective Akt signalling. | Cardiovasc. Res. 99(4):694-704 | |||
| Korkmaz-Icöz S, et al. Mouse over for full list |
(2016) | Left ventricular pressure-volume measurements and myocardial gene expression profile in type 2 diabetic Goto-Kakizaki rats. | Am. J. Physiol. Heart Circ. Physiol. 311(4):H958-H971 | |||
| Xue B, et al. Mouse over for full list |
(2015) | Effects of High Fat Feeding on Adipose Tissue Gene Expression in Diabetic Goto-Kakizaki Rats. | Gene Regul Syst Bio 9:15-26 | Diabetes (Type 2) | ||
| Speck M, et al. Mouse over for full list |
(2011) | Duodenal-jejunal bypass protects GK rats from {beta}-cell loss and aggravation of hyperglycemia and increases enteroendocrine cells coexpressing GIP and GLP-1. | Am. J. Physiol. Endocrinol. Metab. 300(5):E923-32 | |||
| Schrijvers BF, et al. Mouse over for full list |
(2004) | Long-term renal changes in the Goto-Kakizaki rat, a model of lean type 2 diabetes. | Nephrol. Dial. Transplant. 19(5):1092-7 | |||
| Shinde J, et al. Mouse over for full list |
(2008) | Alpha-glucosidase inhibitory activity of Syzygium cumini (Linn.) Skeels seed kernel in vitro and in Goto-Kakizaki (GK) rats. | Carbohydr. Res. 343(7):1278-81 | |||
| Serradas P, et al. Mouse over for full list |
(2002) | Fetal insulin-like growth factor-2 production is impaired in the GK rat model of type 2 diabetes. | Diabetes 51(2):392-7 | |||
| Ragolia L, et al. Mouse over for full list |
(2004) | Inhibition of cell cycle progression and migration of vascular smooth muscle cells by prostaglandin D2 synthase: resistance in diabetic Goto-Kakizaki rats. | Am. J. Physiol., Cell Physiol. 287(5):C1273-81 | |||
| Portha B Mouse over for full list |
(2005) | Programmed disorders of beta-cell development and function as one cause for type 2 diabetes? The GK rat paradigm. | Diabetes Metab. Res. Rev. 21(6):495-504 | |||
| Portha B, et al. Mouse over for full list |
(2009) | The GK rat beta-cell: a prototype for the diseased human beta-cell in type 2 diabetes? | Mol. Cell. Endocrinol. 297(1-2):73-85 | |||
| Portha B, et al. Mouse over for full list |
(2010) | Islet structure and function in the GK rat. | Adv. Exp. Med. Biol. 654:479-500 | |||
| Omri S, et al. Mouse over for full list |
(2010) | The outer limiting membrane (OLM) revisited: clinical implications. | Clin Ophthalmol 4:183-95 | |||
| Omri S, et al. Mouse over for full list |
(2011) | Microglia/macrophages migrate through retinal epithelium barrier by a transcellular route in diabetic retinopathy: role of PKCζ in the Goto Kakizaki rat model. | Am. J. Pathol. 179(2):942-53 | |||
| Nobrega MA, et al. Mouse over for full list |
(2009) | Distinct genetic regulation of progression of diabetes and renal disease in the Goto-Kakizaki rat. | Physiol. Genomics 39(1):38-46 | |||
| Nie J, et al. Mouse over for full list |
(2011) | Differential muscle gene expression as a function of disease progression in Goto-Kakizaki diabetic rats. | Mol. Cell. Endocrinol. 338(1-2):10-7 | |||
| Nie J Mouse over for full list |
(2010) | Muscle biomarkers of type 2 diabetes disease progression in Goto-Kakizaki rats | Dissertation | |||
| Movassat J, et al. Mouse over for full list |
(1997) | Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat. | Diabetologia 40(8):916-25 | |||
| Miyamoto K, et al. Mouse over for full list |
(1996) | Evaluation of retinal microcirculatory alterations in the Goto-Kakizaki rat. A spontaneous model of non-insulin-dependent diabetes. | Invest. Ophthalmol. Vis. Sci. 37(5):898-905 | |||
| Landersdorfer CB, et al. Mouse over for full list |
(2009) | Mechanism-based modeling of nutritional and leptin influences on growth in normal and type 2 diabetic rats. | J. Pharmacol. Exp. Ther. 328(2):644-51 | |||
| Lærke HN, et al. Mouse over for full list |
(2007) | Soluble fiber extracted from potato pulp is highly fermentable but has no effect on risk markers of diabetes and cardiovascular disease in Goto-Kakizaki rats | Nutrition Research. 27(3):152-160 | |||
| Lacraz G, et al. Mouse over for full list |
(2009) | Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat. | PLoS ONE 4(9):e6963 | |||
| King AJ Mouse over for full list |
(2012) | The use of animal models in diabetes research | British Journal of Pharmacolog. 166: 877-894. | |||
| Jørgensen W, et al. Mouse over for full list |
(2012) | Progression of type 2 diabetes in GK rats affects muscle and liver mitochondria differently: pronounced reduction of complex II flux is observed in liver only. | Am. J. Physiol. Endocrinol. Metab. 303(4):E515-23 | |||
| Janssen U, et al. Mouse over for full list |
(1999) | Rodent models of nephropathy associated with type II diabetes. | J. Nephrol. 12(3):159-72 | |||
| Harris AK, et al. Mouse over for full list |
(2005) | Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: role of endothelin-1. | Diabetes 54(9):2638-44 | |||
| Gupte S, et al. Mouse over for full list |
(2010) | Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM. | PLoS ONE 5(7):e11800 | |||
| Grönholm T, et al. Mouse over for full list |
(2005) | Vasopeptidase inhibition has beneficial cardiac effects in spontaneously diabetic Goto-Kakizaki rats. | Eur. J. Pharmacol. 519(3):267-76 | |||
| Guan W, et al. Mouse over for full list |
(2011) | Drug repurposing for vascular protection after acute ischemic stroke. | Acta Neurochir. Suppl. 111:295-8 | Transient Ischemic Attack | ||
| Goto Y, et al. Mouse over for full list |
(1988) | Development of diabetes in the non-obese NIDDM rat (GK rat). | Adv. Exp. Med. Biol. 246:29-31 | |||
| Goto Y, et al. Mouse over for full list |
(1976) | Production of spontaneous diabetic rats by repetition of selective breeding. | Tohoku J. Exp. Med. 119(1):85-90 | |||
| Gauguier D, et al. Mouse over for full list |
(1996) | Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. | Nat. Genet. 12(1):38-43 | |||
| Esguerra JL, et al. Mouse over for full list |
(2011) | Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat. | PLoS ONE 6(4):e18613 | |||
| Desrois M, et al. Mouse over for full list |
(2004) | Gender differences in hypertrophy, insulin resistance and ischemic injury in the aging type 2 diabetic rat heart. | J. Mol. Cell. Cardiol. 37(2):547-55 | |||
| Cao Y, et al. Mouse over for full list |
(2011) | Modeling diabetes disease progression and salsalate intervention in Goto-Kakizaki rats. | J. Pharmacol. Exp. Ther. 339(3):896-904 | |||
| Cao Y, et al. Mouse over for full list |
(2012) | Pharmacokinetics of salsalate and salicylic acid in normal and diabetic rats. | Biopharm Drug Dispos 33(6):285-91 | |||
| Bitar MS, et al. Mouse over for full list |
(2005) | Oxidative stress--mediated alterations in glucose dynamics in a genetic animal model of type II diabetes. | Life Sci. 77(20):2552-73 | |||
| Begum N, et al. Mouse over for full list |
(1998) | Altered regulation of insulin signaling components in adipocytes of insulin-resistant type II diabetic Goto-Kakizaki rats. | Metab. Clin. Exp. 47(1):54-62 | |||
| Beddow SA, et al. Mouse over for full list |
(2012) | Fasting hyperglycemia in the Goto-Kakizaki rat is dependent on corticosterone: a confounding variable in rodent models of type 2 diabetes. | Dis Model Mech 5(5):681-5 | |||
| Barbu A, et al. Mouse over for full list |
(2009) | Pref-1 and adipokine expression in adipose tissues of GK and Zucker rats. | Mol. Cell. Endocrinol. 299(2):163-71 |
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