Cyp3a (8-gene) Knockout Publications

Cyp3a (8-gene) Knockout Model Page

Filter publications by application: All
Filter publications by model type: All



Paper Title


Model Type


Full Text

Eisenmann ED, et al.
Mouse over for full list
Eisenmann ED, Fu Q, Muhowski EM, Jin Y, Uddin ME, Garrison DA, Weber RH, Woyach J, Byrd JC, Sparreboom A, Baker SD
(2021) Intentional Modulation of Ibrutinib Pharmacokinetics through CYP3A Inhibition. Cancer Res Commun 1(2):79-89
Jin Y, et al.
Mouse over for full list
Jin Y, Li Y, Uddin ME, Sparreboom A, Hu S
(2021) Rapid quantification of vincristine in mouse plasma using ESI-LC-MS/MS: Application to pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci 1168:122591
Liu K, et al.
Mouse over for full list
Liu K, Li F, Lu J, Gao Z, Klaassen CD, Ma X
(2014) Role of CYP3A in isoniazid metabolism in vivo. Drug Metab Pharmacokinet 29(2):219-22
Chang JH, et al.
Mouse over for full list
Chang JH, Ly J, Plise E, Zhang X, Messick K, Wright M, Cheong J
(2014) Differential effects of Rifampin and Ketoconazole on the blood and liver concentration of atorvastatin in wild-type and Cyp3a and Oatp1a/b knockout mice. Drug Metab Dispos 42(6):1067-73
Robillard KR, et al.
Mouse over for full list
Robillard KR, Chan GN, Zhang G, la Porte C, Cameron W, Bendayan R
(2014) Role of P-glycoprotein in the distribution of the HIV protease inhibitor atazanavir in the brain and male genital tract. Antimicrob Agents Chemother 58(3):1713-22
Li W, et al.
Mouse over for full list
Li W, Sparidans RW, Martins MLF, El-Lari M, Lebre MC, van Tellingen O, Beijnen JH, Schinkel AH
(2021) ABCB1 and ABCG2 Restrict Brain and Testis Accumulation and, Alongside CYP3A, Limit Oral Availability of the Novel TRK Inhibitor Selitrectinib. Mol Cancer Ther 20(6):1173-1182
van Herwaarden AE, et al.
Mouse over for full list
van Herwaarden AE, Wagenaar E, van der Kruijssen CM, van Waterschoot RA, Smit JW, Song JY, van der Valk MA, van Tellingen O, van der Hoorn JW, Rosing H, Beijnen JH, Schinkel AH
(2007) Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism. J. Clin. Invest. 117(11):3583-92

Welcome! Tell us a little about yourself