Cdh5(PAC)-CreERT2 Mouse Publications

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Sörensen I, et al.
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Sörensen I, Adams RH, Gossler A
(2009) DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. Blood 113(22):5680-8
Wang L, et al.
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Wang L, Benedito R, Bixel MG, Zeuschner D, Stehling M, Sävendahl L, Haigh JJ, Snippert H, Clevers H, Breier G, Kiefer F, Adams RH
(2013) Identification of a clonally expanding haematopoietic compartment in bone marrow. EMBO J. 32(2):219-30
Luxán G, et al.
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Luxán G, Casanova JC, Martínez-Poveda B, Prados B, D'Amato G, MacGrogan D, Gonzalez-Rajal A, Dobarro D, Torroja C, Martinez F, Izquierdo-García JL, Fernández-Friera L, Sabater-Molina M, Kong YY, Pizarro G, Ibañez B, Medrano C, García-Pavía P, Gimeno JR, Monserrat L, Jiménez-Borreguero LJ, de la Pompa JL
(2013) Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat. Med. 19(2):193-201
Nakayama M, et al.
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Nakayama M, Nakayama A, van Lessen M, Yamamoto H, Hoffmann S, Drexler HC, Itoh N, Hirose T, Breier G, Vestweber D, Cooper JA, Ohno S, Kaibuchi K, Adams RH
(2013) Spatial regulation of VEGF receptor endocytosis in angiogenesis. Nat. Cell Biol. 15(3):249-60
Yang H, et al.
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Yang H, Lee S, Lee S, Kim K, Yang Y, Kim JH, Adams RH, Wells JM, Morrison SJ, Koh GY, Kim I
(2013) Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice. J. Clin. Invest. 123(1):418-31
Fantin A, et al.
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Fantin A, Vieira JM, Plein A, Denti L, Fruttiger M, Pollard JW, Ruhrberg C
(2013) NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis. Blood 121(12):2352-62
Jung B, et al.
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Jung B, Obinata H, Galvani S, Mendelson K, Ding BS, Skoura A, Kinzel B, Brinkmann V, Rafii S, Evans T, Hla T
(2012) Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development. Dev. Cell 23(3):600-10
Gaengel K, et al.
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Gaengel K, Niaudet C, Hagikura K, Laviña B, Siemsen BL, Muhl L, Hofmann JJ, Ebarasi L, Nyström S, Rymo S, Chen LL, Pang MF, Jin Y, Raschperger E, Roswall P, Schulte D, Benedito R, Larsson J, Hellström M, Fuxe J, Uhlén P, Adams R, Jakobsson L, Majumdar A, Vestweber D, Uv A, Betsholtz C
(2012) The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2. Dev. Cell 23(3):587-99
Naito H, et al.
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Naito H, Kidoya H, Sakimoto S, Wakabayashi T, Takakura N
(2012) Identification and characterization of a resident vascular stem/progenitor cell population in preexisting blood vessels. EMBO J. 31(4):842-55
Benedito R, et al.
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Benedito R, Rocha SF, Woeste M, Zamykal M, Radtke F, Casanovas O, Duarte A, Pytowski B, Adams RH
(2012) Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling. Nature 484(7392):110-4
Sabine A, et al.
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Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hägerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Mäkinen T, Kiefer F, Kwak BR, Petrova TV
(2012) Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation. Dev. Cell 22(2):430-45
Allinson KR, et al.
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Allinson KR, Lee HS, Fruttiger M, McCarty JH, McCarty J, Arthur HM
(2012) Endothelial expression of TGFβ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous system. PLoS ONE 7(6):e39336
Trindade A, et al.
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Trindade A, Djokovic D, Gigante J, Badenes M, Pedrosa AR, Fernandes AC, Lopes-da-Costa L, Krasnoperov V, Liu R, Gill PS, Duarte A
(2012) Low-dosage inhibition of Dll4 signaling promotes wound healing by inducing functional neo-angiogenesis. PLoS ONE 7(1):e29863
Izumi N, et al.
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Izumi N, Helker C, Ehling M, Behrens A, Herzog W, Adams RH
(2012) Fbxw7 controls angiogenesis by regulating endothelial Notch activity. PLoS ONE 7(7):e41116
Fan Y, et al.
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Fan Y, Arif A, Gong Y, Jia J, Eswarappa SM, Willard B, Horowitz A, Graham LM, Penn MS, Fox PL
(2012) Stimulus-dependent phosphorylation of profilin-1 in angiogenesis. Nat. Cell Biol. 14(10):1046-56
Ding BS, et al.
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Ding BS, Nolan DJ, Guo P, Babazadeh AO, Cao Z, Rosenwaks Z, Crystal RG, Simons M, Sato TN, Worgall S, Shido K, Rabbany SY, Rafii S
(2011) Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell 147(3):539-53
Boulday G, et al.
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Boulday G, Rudini N, Maddaluno L, Blécon A, Arnould M, Gaudric A, Chapon F, Adams RH, Dejana E, Tournier-Lasserve E
(2011) Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice. J. Exp. Med. 208(9):1835-47
Bréart B, et al.
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Bréart B, Ramos-Perez WD, Mendoza A, Salous AK, Gobert M, Huang Y, Adams RH, Lafaille JJ, Escalante-Alcalde D, Morris AJ, Schwab SR
(2011) Lipid phosphate phosphatase 3 enables efficient thymic egress. J. Exp. Med. 208(6):1267-78
Hoch M, et al.
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Hoch M, Fischer P, Stapel B, Missol-Kolka E, Sekkali B, Scherr M, Favret F, Braun T, Eder M, Schuster-Gossler K, Gossler A, Hilfiker A, Balligand JL, Drexler H, Hilfiker-Kleiner D
(2011) Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies. Cell Stem Cell 9(2):131-43
Dellavalle A, et al.
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Dellavalle A, Maroli G, Covarello D, Azzoni E, Innocenzi A, Perani L, Antonini S, Sambasivan R, Brunelli S, Tajbakhsh S, Cossu G
(2011) Pericytes resident in postnatal skeletal muscle differentiate into muscle fibres and generate satellite cells. Nat Commun 2:499
Luna-Zurita L, et al.
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Luna-Zurita L, Prados B, Grego-Bessa J, Luxán G, del Monte G, Benguría A, Adams RH, Pérez-Pomares JM, de la Pompa JL
(2010) Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. J. Clin. Invest. 120(10):3493-507
Wang Y, et al.
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Wang Y, Nakayama M, Pitulescu ME, Schmidt TS, Bochenek ML, Sakakibara A, Adams S, Davy A, Deutsch U, Lüthi U, Barberis A, Benjamin LE, Mäkinen T, Nobes CD, Adams RH
(2010) Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature 465(7297):483-6
Robson A, et al.
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Robson A, Allinson KR, Anderson RH, Henderson DJ, Arthur HM
(2010) The TGFβ type II receptor plays a critical role in the endothelial cells during cardiac development. Dev. Dyn. 239(9):2435-42
Mahmoud M, et al.
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Mahmoud M, Allinson KR, Zhai Z, Oakenfull R, Ghandi P, Adams RH, Fruttiger M, Arthur HM
(2010) Pathogenesis of arteriovenous malformations in the absence of endoglin. Circ. Res. 106(8):1425-33
Bazigou E, et al.
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Bazigou E, Xie S, Chen C, Weston A, Miura N, Sorokin L, Adams R, Muro AF, Sheppard D, Makinen T
(2009) Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev. Cell 17(2):175-86
Benedito R, et al.
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Benedito R, Roca C, Sörensen I, Adams S, Gossler A, Fruttiger M, Adams RH
(2009) The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137(6):1124-35