Black 6 (B6NTac) Publications

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Filter publications by application: All Addiction Alzheimer's Autoimmune Behavior Cardiovascular Colitis Colon Cancer Development Diabetes (Type 1) Diabetes (Type 2) Experimental Autoimmune Encephalomyelitis (EAE) Gastrointestinal General HIV Immuno-Oncology Immunology Immunotherapy Infectious Disease Inflammation Leukemia Lymphoma Malaria Melanoma Metabolic Syndrome Metabolism Microbiome Multiple Sclerosis NK Neuroscience Oncology Parkinson's Stem Cells/Regenerative Medicine/Tissue Engineering T And/Or B Cell Function Transient Ischemic Attack Vaccine Research Virology
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Peng S, et al.
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Peng S, Ferrall L, Gaillard S, Wang C, Chi WY, Huang CH, Roden RBS, Wu TC, Chang YN, Hung CF
(2021) Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody. mBio 12(1)
Oncology, Vaccine Research, Immuno-Oncology
Mekada K, et al.
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Mekada K, Yoshiki A
(2021) Substrains matter in phenotyping of C57BL/6 mice. Exp Anim
Bains RS, et al.
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Bains RS, Cater HL, Stewart M, Scudamore CL, Wells SE
(2020) The effects of microchipping C57BL/6N mice on standard phenotyping tests. F1000Res 9:20
Williams JL, et al.
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Williams JL, Paudyal A, Awad S, Nicholson J, Grzesik D, Botta J, Meimaridou E, Maharaj AV, Stewart M, Tinker A, Cox RD, Metherell LA
(2020) Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas null C57BL/6J mice do not. Life Sci Alliance 3(4)
Viennois E, et al.
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Viennois E, Bretin A, Dubé PE, Maue AC, Dauriat CJG, Barnich N, Gewirtz AT, Chassaing B
(2020) Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation. Cell Rep 33(1):108229
Colitis, Microbiome
Wu L, et al.
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Wu L, Hollinshead KER, Hao Y, Au C, Kroehling L, Ng C, Lin WY, Li D, Silva HM, Shin J, Lafaille JJ, Possemato R, Pacold ME, Papagiannakopoulos T, Kimmelman AC, Satija R, Littman DR
(2020) Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy. Cell
Experimental Autoimmune Encephalomyelitis (EAE), T And/Or B Cell Function, Inflammation
Funabashi M, et al.
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Funabashi M, Grove TL, Wang M, Varma Y, McFadden ME, Brown LC, Guo C, Higginbottom S, Almo SC, Fischbach MA
(2020) A metabolic pathway for bile acid dehydroxylation by the gut microbiome. Nature 582(7813):566-570
Microbiome
Zhang J, et al.
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Zhang J, Winters K, Kiser K, Baboli M, Kim SG
(2020) Assessment of tumor treatment response using active contrast encoding (ACE)-MRI: Comparison with conventional DCE-MRI. PLoS ONE 15(6):e0234520
Oncology
Buss CG, et al.
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Buss CG, Bhatia SN
(2020) Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics. Proc. Natl. Acad. Sci. U.S.A.
Mishra M, et al.
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Mishra M, Muthuramu I, Kempen H, De Geest B
(2020) Administration of apo A-I (Milano) nanoparticles reverses pathological remodelling, cardiac dysfunction, and heart failure in a murine model of HFpEF associated with hypertension. Sci Rep 10(1):8382
Cardiovascular
Mercer HL, et al.
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Mercer HL, Snyder LM, Doherty CM, Fox BA, Bzik DJ, Denkers EY
(2020) Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity. PLoS Pathog. 16(5):e1008572
Yang WS, et al.
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Yang WS, Kim HG, Kim E, Han SY, Aziz N, Yi YS, Kim S, Lee Y, Yoo BC, Han JW, Parameswaran N, Kim JH, Cho JY
(2020) Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses. Cells 9(5)
Inflammation
Campbell C, et al.
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Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY
(2020) Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. Nature 581(7809):475-479
T And/Or B Cell Function, Microbiome
Lundberg R, et al.
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Lundberg R, Toft MF, Metzdorff SB, Hansen CHF, Licht TR, Bahl MI, Hansen AK
(2020) Human microbiota-transplanted C57BL/6 mice and offspring display reduced establishment of key bacteria and reduced immune stimulation compared to mouse microbiota-transplantation. Sci Rep 10(1):7805
Immunology, Microbiome
Earl PL, et al.
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Earl PL, Americo JL, Moss B
(2020) Natural killer cells expanded in vivo or ex vivo with IL-15 overcomes the inherent susceptibility of CAST mice to lethal infection with orthopoxviruses. PLoS Pathog. 16(4):e1008505
Kadekar D, et al.
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Kadekar D, Agerholm R, Rizk J, Neubauer HA, Suske T, Maurer B, Viñals MT, Comelli EM, Taibi A, Moriggl R, Bekiaris V
(2020) The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5. J. Clin. Invest.
Shui L, et al.
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Shui L, Yang X, Li J, Yi C, Sun Q, Zhu H
(2019) Gut Microbiome as a Potential Factor for Modulating Resistance to Cancer Immunotherapy. Front Immunol 10:2989
Immunology, Microbiome, Oncology
Hathaway-Schrader JD, et al.
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Hathaway-Schrader JD, Poulides NA, Carson MD, Kirkpatrick JE, Warner AJ, Swanson BA, Taylor EV, Chew ME, Reddy SV, Liu B, Westwater C, Novince CM
(2020) Specific Commensal Bacterium Critically Regulates Gut Microbiota Osteoimmunomodulatory Actions During Normal Postpubertal Skeletal Growth and Maturation. JBMR Plus 4(3):e10338
Microbiome
Lion M, et al.
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Lion M, Muhire B, Namiki Y, Tolstorukov MY, Oettinger MA
(2020) Alterations in chromatin at antigen receptor loci define lineage progression during B lymphopoiesis. Proc. Natl. Acad. Sci. U.S.A. 117(10):5453-5462
T And/Or B Cell Function
Osbelt L, et al.
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Osbelt L, Thiemann S, Smit N, Lesker TR, Schröter M, Gálvez EJC, Schmidt-Hohagen K, Pils MC, Mühlen S, Dersch P, Hiller K, Schlüter D, Neumann-Schaal M, Strowig T
(2020) Variations in microbiota composition of laboratory mice influence Citrobacter rodentium infection via variable short-chain fatty acid production. PLoS Pathog. 16(3):e1008448
Microbiome
Moreau M, et al.
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Moreau M, Ibeh U, Decosmo K, Bih N, Yasmin-Karim S, Toyang N, Lowe H, Ngwa W
(2019) Cannabis Flavonoid Derivative of Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer. Front Oncol 9:660
Bando JK, et al.
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Bando JK, Gilfillan S, Di Luccia B, Fachi JL, Sécca C, Cella M, Colonna M
(2020) ILC2s are the predominant source of intestinal ILC-derived IL-10. J. Exp. Med. 217(2)
Gastrointestinal, T And/Or B Cell Function, Inflammation
Enríquez Pérez J, et al.
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Enríquez Pérez J, Kopecky J, Visse E, Darabi A, Siesjö P
(2020) Convection-enhanced delivery of temozolomide and whole cell tumor immunizations in GL261 and KR158 experimental mouse gliomas. BMC Cancer 20(1):7
Oncology
Peng YC, et al.
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Peng YC, Qi Y, Zhang C, Yao X, Wu J, Pattaradilokrat S, Xia L, Tumas KC, He X, Ishizaki T, Qi CF, Holder AA, Myers TG, Long CA, Kaneko O, Li J, Su XZ
(2020) Plasmodium yoelii Erythrocyte-Binding-like Protein Modulates Host Cell Membrane Structure, Immunity, and Disease Severity. mBio 11(1)
Malaria
Tarumoto Y, et al.
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Tarumoto Y, Lin S, Wang J, Milazzo JP, Xu Y, Lu B, Yang Z, Wei Y, Polyanskaya S, Wunderlich M, Gray NS, Stegmaier K, Vakoc CR
(2020) Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo. Blood 135(1):56-70
Leukemia
Christensen IB, et al.
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Christensen IB, Wu Q, Bohlbro AS, Skals MG, Damkier HH, Hübner CA, Fenton RA, Praetorius J
(2020) Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium. Fluids Barriers CNS 17(1):2
Chen X, et al.
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Chen X, Sanchez GN, Schnitzer MJ, Delp SL
(2020) Microendoscopy detects altered muscular contractile dynamics in a mouse model of amyotrophic lateral sclerosis. Sci Rep 10(1):457
Neuroscience
Reed MD, et al.
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Reed MD, Yim YS, Wimmer RD, Kim H, Ryu C, Welch GM, Andina M, King HO, Waisman A, Halassa MM, Huh JR, Choi GB
(2020) IL-17a promotes sociability in mouse models of neurodevelopmental disorders. Nature 577(7789):249-253
Neuroscience
Stampouloglou E, et al.
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Stampouloglou E, Cheng N, Federico A, Slaby E, Monti S, Szeto GL, Varelas X
(2020) Yap suppresses T-cell function and infiltration in the tumor microenvironment. PLoS Biol. 18(1):e3000591
T And/Or B Cell Function, Oncology
Brown TA, et al.
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Brown TA, Tashiro H, Kasahara DI, Cho Y, Shore SA
(2020) Early life microbiome perturbation alters pulmonary responses to ozone in male mice. Physiol Rep 8(2):e14290
Microbiome
Smith AD, et al.
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Smith AD, Foss ED, Zhang I, Hastie JL, Giordano NP, Gasparyan L, VinhNguyen LP, Schubert AM, Prasad D, McMichael HL, Sun J, Beger RD, Simonyan V, Cowley SC, Carlson PE
(2019) Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection. PLoS ONE 14(9):e0223025
Microbiome
Bittermann E, et al.
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Bittermann E, Abdelhamed Z, Liegel RP, Menke C, Timms A, Beier DR, Stottmann RW
(2019) Differential requirements of tubulin genes in mammalian forebrain development. PLoS Genet. 15(8):e1008243
Neuroscience, Development
Cho Y, et al.
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Cho Y, Osgood RS, Bell LN, Karoly ED, Shore SA
(2019) Ozone-induced changes in the serum metabolome: Role of the microbiome. PLoS ONE 14(8):e0221633
Microbiome
Svensson KA, et al.
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Svensson KA, Heinz BA, Schaus JM, Beck JP, Hao J, Krushinski JH, Reinhard MR, Cohen MP, Hellman SL, Getman BG, Wang X, Menezes MM, Maren DL, Falcone JF, Anderson WH, Wright RA, Morin SM, Knopp KL, Adams BL, Rogovoy B, Okun I, Suter TM, Statnick MA, Gehlert DR, Nelson DL, Lucaites VL, Emkey R, DeLapp NW, Wiernicki TR, Cramer JW, Yang CR, Bruns RF
(2017) An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis. J. Pharmacol. Exp. Ther. 360(1):117-128
Neuroscience
Lee MJ, et al.
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Lee MJ, Choi JH, Lee SJ, Cho IH
(2017) Oriental Medicine Samhwangsasim-tang Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Th1 Cell Responses and Upregulating Treg Cell Responses. Front Pharmacol 8:192
Experimental Autoimmune Encephalomyelitis (EAE), Inflammation
DeMars KM, et al.
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DeMars KM, Pacheco SC, Yang C, Siwarski DM, Candelario-Jalil E
(2017) Selective Inhibition of Janus Kinase 3 Has No Impact on Infarct Size or Neurobehavioral Outcomes in Permanent Ischemic Stroke in Mice. Front Neurol 8:363
Transient Ischemic Attack
Mett V, et al.
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Mett V, Komarova EA, Greene K, Bespalov I, Brackett C, Gillard B, Gleiberman AS, Toshkov IA, Aygün-Sunar S, Johnson C, Karasik E, Bapardekar-Nair M, Kurnasov OV, Osterman AL, Stanhope-Baker PS, Morrison C, Moser MT, Foster BA, Gudkov AV
(2018) Mobilan: a recombinant adenovirus carrying Toll-like receptor 5 self-activating cassette for cancer immunotherapy. Oncogene 37(4):439-449
Immunotherapy
Vandermosten L, et al.
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Vandermosten L, De Geest C, Knoops S, Thijs G, Chapman KE, De Bosscher K, Opdenakker G, Van den Steen PE
(2017) 11β-hydroxysteroid dehydrogenase type 1 has no effect on survival during experimental malaria but affects parasitemia in a parasite strain-specific manner. Sci Rep 7(1):13835
Immunology, Malaria
Wahlund CJE, et al.
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Wahlund CJE, Güclüler G, Hiltbrunner S, Veerman RE, Näslund TI, Gabrielsson S
(2017) Exosomes from antigen-pulsed dendritic cells induce stronger antigen-specific immune responses than microvesicles in vivo. Sci Rep 7(1):17095
Immunology
Yang Y, et al.
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Yang Y, Boza-Serrano A, Dunning CJR, Clausen BH, Lambertsen KL, Deierborg T
(2018) Inflammation leads to distinct populations of extracellular vesicles from microglia. J Neuroinflammation 15(1):168
Inflammation, Neuroscience
Hart ML, et al.
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Hart ML, Ericsson AC, Lloyd KCK, Grimsrud KN, Rogala AR, Godfrey VL, Nielsen JN, Franklin CL
(2018) Development of outbred CD1 mouse colonies with distinct standardized gut microbiota profiles for use in complex microbiota targeted studies. Sci Rep 8(1):10107
Microbiome
Rogers TD, et al.
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Rogers TD, Ostrowski LE, Livraghi-Butrico A, Button B, Grubb BR
(2018) Mucociliary Clearance in Mice Measured by Tracking Trans-tracheal Fluorescence of Nasally Aerosolized Beads. Sci Rep 8(1):14744
Knuhr K, et al.
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Knuhr K, Langhans K, Nyenhuis S, Viertmann K, Kildemoes AMO, Doenhoff MJ, Haas H, Schramm G
(2018) Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses Basophil Interleukin (IL)-4 and IL-13. Front Immunol 9:2293
Inflammation
Scheiman J, et al.
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Scheiman J, Luber JM, Chavkin TA, MacDonald T, Tung A, Pham LD, Wibowo MC, Wurth RC, Punthambaker S, Tierney BT, Yang Z, Hattab MW, Avila-Pacheco J, Clish CB, Lessard S, Church GM, Kostic AD
(2019) Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism. Nat. Med.
Microbiome
Mardani I, et al.
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Mardani I, Tomas Dalen K, Drevinge C, Miljanovic A, Ståhlman M, Klevstig M, Scharin Täng M, Fogelstrand P, Levin M, Ekstrand M, Nair S, Redfors B, Omerovic E, Andersson L, Kimmel AR, Borén J, Levin MC
(2019) Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart. Sci Rep 9(1):6909
Cardiovascular
Vetere G, et al.
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Vetere G, Tran LM, Moberg S, Steadman PE, Restivo L, Morrison FG, Ressler KJ, Josselyn SA, Frankland PW
(2019) Memory formation in the absence of experience. Nat. Neurosci.
Behavior, Neuroscience
Li SX, et al.
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Li SX, Sen S, Schneider JM, Xiong KN, Nusbacher NM, Moreno-Huizar N, Shaffer M, Armstrong AJS, Severs E, Kuhn K, Neff CP, McCarter M, Campbell T, Lozupone CA, Palmer BE
(2019) Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection. PLoS Pathog. 15(4):e1007611
HIV, Microbiome
Zhong Y, et al.
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Zhong Y, Ma Z, Zhu S, Yue J, Zhang M, Antaris AL, Yuan J, Cui R, Wan H, Zhou Y, Wang W, Huang NF, Luo J, Hu Z, Dai H
(2017) Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500 nm. Nat Commun 8(1):737
Blumenfeld NR, et al.
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Blumenfeld NR, Kang HJ, Fenzl A, Song Z, Chung JJ, Singh R, Johnson R, Karakecili A, Feranil JB, Rossen NS, Zhang V, Jaggi S, McCarty B, Bessler S, Schwartz GJ, Grant R, Korner J, Kiefer FW, Gillette BM, Sia SK
(2018) A direct tissue-grafting approach to increasing endogenous brown fat. Sci Rep 8(1):7957
Stem Cells/Regenerative Medicine/Tissue Engineering, Metabolic Syndrome
Chakravarty S, et al.
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Chakravarty S, Mandal RK, Duff ML, Schmidt NW
(2019) Intestinal short-chain fatty acid composition does not explain gut microbiota-mediated effects on malaria severity. PLoS ONE 14(3):e0214449
Malaria, Microbiome
Kasper L, et al.
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Kasper L, König A, Koenig PA, Gresnigt MS, Westman J, Drummond RA, Lionakis MS, Groß O, Ruland J, Naglik JR, Hube B
(2018) The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes. Nat Commun 9(1):4260
Infectious Disease
Gopal R, et al.
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Gopal R, Lee B, McHugh KJ, Rich HE, Ramanan K, Mandalapu S, Clay ME, Seger PJ, Enelow RI, Manni ML, Robinson KM, Rangel-Moreno J, Alcorn JF
(2018) STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection. Front Immunol 9:2151
Infectious Disease
Webb LM, et al.
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Webb LM, Narvaez Miranda J, Amici SA, Sengupta S, Nagy G, Guerau-de-Arellano M
(2019) NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms. Front Immunol 10:524
Multiple Sclerosis
Li N, et al.
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Li N, Matte-Martone C, Zheng H, Cui W, Venkatesan S, Tan HS, McNiff J, Demetris AJ, Roopenian D, Kaech S, Shlomchik WD
(2011) Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution. Blood 118(22):5965-76
T And/Or B Cell Function, Leukemia
Puzan M, et al.
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Puzan M, Hosic S, Ghio C, Koppes A
(2018) Enteric Nervous System Regulation of Intestinal Stem Cell Differentiation and Epithelial Monolayer Function. Sci Rep 8(1):6313
Gastrointestinal
Popper B, et al.
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Popper B, Demleitner A, Bolivar VJ, Kusek G, Snyder-Keller A, Schieweck R, Temple S, Kiebler MA
(2018) Staufen2 deficiency leads to impaired response to novelty in mice. Neurobiol Learn Mem 150:107-115
Behavior
Ronca AE, et al.
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Ronca AE, Moyer EL, Talyansky Y, Lowe M, Padmanabhan S, Choi S, Gong C, Cadena SM, Stodieck L, Globus RK
(2019) Behavior of mice aboard the International Space Station. Sci Rep 9(1):4717
Baumgärtel K, et al.
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Baumgärtel K, Green A, Hornberger D, Lapira J, Rex C, Wheeler DG, Peters M
(2018) PDE4D regulates Spine Plasticity and Memory in the Retrosplenial Cortex. Sci Rep 8(1):3895
Neuroscience
Takahashi T, et al.
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Takahashi T, Katano I, Ito R, Goto M, Abe H, Mizuno S, Kawai K, Sugiyama F, Ito M
(2017) Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis. Front Immunol 8:2017
Immunology
Matic S, et al.
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Matic S, Jiang M, Nicholls TJ, Uhler JP, Dirksen-Schwanenland C, Polosa PL, Simard ML, Li X, Atanassov I, Rackham O, Filipovska A, Stewart JB, Falkenberg M, Larsson NG, Milenkovic D
(2018) Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nat Commun 9(1):1202
Duncan CG, et al.
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Duncan CG, Grimm SA, Morgan DL, Bushel PR, Bennett BD, , Roberts JD, Tyson FL, Merrick BA, Wade PA
(2018) Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver. Sci Rep 8(1):10138
Zhang B, et al.
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Zhang B, Fu D, Xu Q, Cong X, Wu C, Zhong X, Ma Y, Lv Z, Chen F, Han L, Qian M, Chin YE, Lam EW, Chiao P, Sun Y
(2018) The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1. Nat Commun 9(1):1723
Oncology
Jaeger BN, et al.
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Jaeger BN, Linker SB, Parylak SL, Barron JJ, Gallina IS, Saavedra CD, Fitzpatrick C, Lim CK, Schafer ST, Lacar B, Jessberger S, Gage FH
(2018) A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons. Nat Commun 9(1):3084
Neuroscience
Hyrenius-Wittsten A, et al.
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Hyrenius-Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh MP, Song G, Kazi JU, Liu J, Ramakrishan R, Garcia-Ruiz C, Nance S, Gupta P, Zhang J, Rönnstrand L, Hultquist A, Downing JR, Lindkvist-Petersson K, Paulsson K, Järås M, Gruber TA, Ma J, Hagström-Andersson AK
(2018) De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia. Nat Commun 9(1):1770
Leukemia
Buus TB, et al.
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Buus TB, Ødum N, Geisler C, Lauritsen JPH
(2017) Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus. Nat Commun 8(1):1911
T And/Or B Cell Function
Lee S, et al.
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Lee S, Salapa HE, Levin MC
(2019) Localization of near-infrared labeled antibodies to the central nervous system in experimental autoimmune encephalomyelitis. PLoS ONE 14(2):e0212357
Autoimmune
Wang Z, et al.
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Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM
(2019) Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade. Nat. Med. 25(1):141-151
Oncology
Kosik I, et al.
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Kosik I, Angeletti D, Gibbs JS, Angel M, Takeda K, Kosikova M, Nair V, Hickman HD, Xie H, Brooke CB, Yewdell JW
(2019) Neuraminidase inhibition contributes to influenza A virus neutralization by anti-hemagglutinin stem antibodies. J. Exp. Med. 216(2):304-316
Vaccine Research, Virology
Vandenberghe ME, et al.
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Vandenberghe ME, Souedet N, Hérard AS, Ayral AM, Letronne F, Balbastre Y, Sadouni E, Hantraye P, Dhenain M, Frouin F, Lambert JC, Delzescaux T
(2018) Voxel-Based Statistical Analysis of 3D Immunostained Tissue Imaging Front Neurosci 12:754
Dahl SL, et al.
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Dahl SL, Woodworth JS, Lerche CJ, Cramer EP, Nielsen PR, Moser C, Thomsen AR, Borregaard N, Cowland JB
(2018) Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis Front Immunol 9:2717
Ge Z, et al.
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Ge Z, Sheh A, Feng Y, Muthupalani S, Ge L, Wang C, Kurnick S, Mannion A, Whary MT, Fox JG
(2018) Helicobacter pylori-infected C57BL/6 mice with different gastrointestinal microbiota have contrasting gastric pathology, microbial and host immune responses. Sci Rep 8(1):8014
Gastrointestinal, Microbiome
McIntosh CM, et al.
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McIntosh CM, Chen L, Shaiber A, Eren AM, Alegre ML
(2018) Gut microbes contribute to variation in solid organ transplant outcomes in mice. Microbiome 6(1):96
Microbiome
Hryckowian AJ, et al.
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Hryckowian AJ, Van Treuren W, Smits SA, Davis NM, Gardner JO, Bouley DM, Sonnenburg JL
(2018) Microbiota-accessible carbohydrates suppress Clostridium difficile infection in a murine model. Nat Microbiol
Colitis, Infectious Disease, Microbiome
Zhou Y, et al.
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Zhou Y, Dong F, Lanz TA, Reinhart V, Li M, Liu L, Zou J, Xi HS, Mao Y
(2018) Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment. Mol. Psychiatry 23(4):952-962
Neuroscience
Miranda PM, et al.
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Miranda PM, De Palma G, Serkis V, Lu J, Louis-Auguste MP, McCarville JL, Verdu EF, Collins SM, Bercik P
(2018) High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production. Microbiome 6(1):57
Autoimmune, Colitis, Microbiome
Moloney GM, et al.
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Moloney GM, Viola MF, Hoban AE, Dinan TG, Cryan JF
(2017) Faecal microRNAs: indicators of imbalance at the host-microbe interface? Benef Microbes :1-10
Microbiome
Mao K, et al.
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Mao K, Baptista AP, Tamoutounour S, Zhuang L, Bouladoux N, Martins AJ, Huang Y, Gerner MY, Belkaid Y, Germain RN
(2018) Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism. Nature
Immunology, Microbiome
Qin Y, et al.
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Qin Y, Roberts JD, Grimm SA, Lih FB, Deterding LJ, Li R, Chrysovergis K, Wade PA
(2018) An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression. Genome Biol. 19(1):7
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Oncology, Leukemia, Stem Cells/Regenerative Medicine/Tissue Engineering
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Oncology, Leukemia
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Oncology
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Oncology
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Oncology, Vaccine Research
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Neuroscience
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Neuroscience
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Neuroscience
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Neuroscience
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Neuroscience
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Neuroscience
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Microbiome
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Microbiome
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Inflammation, Microbiome
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Microbiome
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Microbiome
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Microbiome
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Microbiome
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Microbiome
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Microbiome
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Infectious Disease
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Infectious Disease, Microbiome
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Microbiome, Metabolic Syndrome
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Infectious Disease
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Diabetes (Type 1), Infectious Disease, Microbiome, Diabetes (Type 2)
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Metabolic Syndrome
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Diabetes (Type 1), Infectious Disease
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Deshpande D, Kethireddy S, Gattacceca F, Amiji M
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Infectious Disease
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Clemmensen C, Madsen AN, Smajilovic S, Holst B, Bräuner-Osborne H
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Infectious Disease
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Clements ME, Chaber CJ, Ledbetter SR, Zuk A
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Infectious Disease
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Infectious Disease
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Infectious Disease, Microbiome
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Billaud M, Johnstone SR, Isakson BE
(2012) Loss of compliance in small arteries, but not in conduit arteries, after 6 weeks exposure to high fat diet. J Cardiovasc Transl Res 5(3):256-63
Infectious Disease
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Infectious Disease
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Bay P, Rowlandson S, Kraft J, Peshavaria M, Jetton T
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Infectious Disease
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Almind K, Kahn CR
(2004) Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes 53(12):3274-85
Cardiovascular, Metabolism
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Robinson KM, McHugh KJ, Mandalapu S, Clay ME, Lee B, Scheller EV, Enelow RI, Chan YR, Kolls JK, Alcorn JF
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Infectious Disease
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Pak-Wittel MA, Yang L, Sojka DK, Rivenbark JG, Yokoyama WM
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Infectious Disease
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Navabi N, Johansson ME, Raghavan S, Lindén SK
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Infectious Disease
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Infectious Disease
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Infectious Disease
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Hempel C, Hyttel P, Staalsø T, Nyengaard JR, Kurtzhals JA
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Infectious Disease, Malaria
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Hempel C, Hyttel P, Kurtzhals JA
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Infectious Disease, Malaria
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Hempel C, Hoyer N, Kildemoes A, Jendresen CB, Kurtzhals JA
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Infectious Disease, Malaria
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Flach CF, Mozer M, Sundquist M, Holmgren J, Raghavan S
(2012) Mucosal vaccination increases local chemokine production attracting immune cells to the stomach mucosa of Helicobacter pylori infected mice. Vaccine 30(9):1636-43
Infectious Disease, Vaccine Research
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Chen W, Bennink JR, Morton PA, Yewdell JW
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T And/Or B Cell Function, Infectious Disease
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Puchta A, Verschoor CP, Thurn T, Bowdish DM
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Infectious Disease
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Immunology
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Gan Y, Tang Z, Yin JX, Shi J, Li L, Shi F, Coons S
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Immunology
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Immunology
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Immunology, NK
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Tang Z, Yin JX, Han P, Gan Y, Coons SW, Wang C, Maalouf M, Shi J
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Immunology
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Immunology
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Immunology
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Immunology
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Immunology
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Immunology
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Immunology
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Immunology
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Ma S, Richardson JA, Bitmansour A, Solberg TD, Pidikiti R, Song K, Stojadinovic S, Vitetta ES, Meyer JJ
(2013) Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation. PLoS ONE 8(2):e56607
Immunology, T And/Or B Cell Function
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Liang SC, Moskalenko M, Van Roey M, Jooss K
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Immunology, T And/Or B Cell Function
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Immunology
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Kim DY, Hao J, Liu R, Turner G, Shi FD, Rho JM
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Immunology
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Immunology
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Källberg E, Ivars F, Leanderson T
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Immunology
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Joseph A, Neff K, Richard J, Gao L, Bangari D, Joly M, Culm-Merdek K, Garman R, Williams J, Richards S, Ruzek M
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Immunology
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Immunology
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Huang Z, Zhao C, Chen Y, Cowell JA, Wei G, Kultti A, Huang L, Thompson CB, Rosengren S, Frost GI, Shepard HM
(2014) Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation. J. Immunol. 192(11):5285-95
Immunology
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Immunology
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Guo Z, Tilburgs T, Wong B, Strominger JL
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Immunology
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Immunology
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Immunology
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Dolina JS, Sung SS, Novobrantseva TI, Nguyen TM, Hahn YS
(2013) Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity. Mol Ther Nucleic Acids 2:e72
Immunology
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Immunology
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Spindler TJ, Tseng AW, Zhou X, Adams GB
(2014) Adipocytic cells augment the support of primitive hematopoietic cells in vitro but have no effect in the bone marrow niche under homeostatic conditions. Stem Cells Dev. 23(4):434-41
Immunology
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Gray PM, Forrest G, Wisniewski T, Porter G, Freed DC, DeMartino JA, Zaller DM, Guo Z, Leone J, Fu TM, Vora KA
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General
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Erlebacher A, Lukens AK, Glimcher LH
(2002) Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo. Proc. Natl. Acad. Sci. U.S.A. 99(26):16940-5
Immunology
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Brodfuehrer J, Rankin A, Edmonds J, Keegan S, Andreyeva T, Lawrence-Henderson R, Ozer J, Gao H, Bloom L, Boisvert A, Lam K, Lee J, LaBranche T, Syed J, Miao W, Singh P
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Immunology
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Baqai FP, Gridley DS, Slater JM, Luo-Owen X, Stodieck LS, Ferguson V, Chapes SK, Pecaut MJ
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Immunology
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Mekada K, Abe K, Murakami A, Nakamura S, Nakata H, Moriwaki K, Obata Y, Yoshiki A
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Mattapallil MJ, et al.
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Mattapallil MJ, Wawrousek EF, Chan CC, Zhao H, Roychoudhury J, Ferguson TA, Caspi RR
(2012) The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes. Invest. Ophthalmol. Vis. Sci. 53(6):2921-7
Jiu-Zhen Jin and Jixiang Ding
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Jiu-Zhen Jin and Jixiang Ding
(2015) Strain-Dependent Gene Expression during Mouse Embryonic Palate Development J. Dev. Biol.
Simon MM, et al.
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Simon MM, Greenaway S, White JK, Fuchs H, Gailus-Durner V, Wells S, Sorg T, Wong K, Bedu E, Cartwright EJ, Dacquin R, Djebali S, Estabel J, Graw J, Ingham NJ, Jackson IJ, Lengeling A, Mandillo S, Marvel J, Meziane H, Preitner F, Puk O, Roux M, Adams DJ, Atkins S, Ayadi A, Becker L, Blake A, Brooker D, Cater H, Champy MF, Combe R, Danecek P, di Fenza A, Gates H, Gerdin AK, Golini E, Hancock JM, Hans W, Hölter SM, Hough T, Jurdic P, Keane TM, Morgan H, Müller W, Neff F, Nicholson G, Pasche B, Roberson LA, Rozman J, Sanderson M, Santos L, Selloum M, Shannon C, Southwell A, Tocchini-Valentini GP, Vancollie VE, Westerberg H, Wurst W, Zi M, Yalcin B, Ramirez-Solis R, Steel KP, Mallon AM, de Angelis MH, Herault Y, Brown SD
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Hattori T, Saban DR, Emami-Naeini P, Chauhan SK, Funaki T, Ueno H, Dana R
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General
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Cunnusamy K, Niederkorn JY
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General
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General
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General
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General, T And/Or B Cell Function
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Ryder E, Doe B, Gleeson D, Houghton R, Dalvi P, Grau E, Habib B, Miklejewska E, Newman S, Sethi D, Sinclair C, Vyas S, Wardle-Jones H, , Bottomley J, Bussell J, Galli A, Salisbury J, Ramirez-Solis R
(2014) Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase. Transgenic Res. 23(1):177-85
General
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Rodríguez-Piñeiro AM, Bergström JH, Ermund A, Gustafsson JK, Schütte A, Johansson ME, Hansson GC
(2013) Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins. Am. J. Physiol. Gastrointest. Liver Physiol. 305(5):G348-56
Gastrointestinal, General
Radetsky LC, et al.
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Radetsky LC, Rea MS, Bierman A, Figueiro MG
(2013) Circadian Disruption: comparing humans with mice. Chronobiol. Int. 30(8):1066-71
General
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Poor SH, Qiu Y, Fassbender ES, Shen S, Woolfenden A, Delpero A, Kim Y, Buchanan N, Gebuhr TC, Hanks SM, Meredith EL, Jaffee BD, Dryja TP
(2014) Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation. Invest. Ophthalmol. Vis. Sci. 55(10):6525-34
General
Platt KM, et al.
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Platt KM, Charnigo RJ, Kincer JF, Dickens BJ, Pearson KJ
(2013) Controlled exercise is a safe pregnancy intervention in mice. J. Am. Assoc. Lab. Anim. Sci. 52(5):524-30
General
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Nyman LR, Cox KB, Hoppel CL, Kerner J, Barnoski BL, Hamm DA, Tian L, Schoeb TR, Wood PA
(2005) Homozygous carnitine palmitoyltransferase 1a (liver isoform) deficiency is lethal in the mouse. Mol. Genet. Metab. 86(1-2):179-87
General
Nguyen D, et al.
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Nguyen D, Samson SL, Reddy VT, Gonzalez EV, Sekhar RV
(2013) Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione. Aging Cell 12(3):415-25
General
Muise ES, et al.
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Muise ES, Zhu Y, Verras A, Karanam BV, Gorski J, Weingarth D, Lin HV, Hwa J, Thompson JR, Hu G, Liu J, He S, DeVita RJ, Shen DM, Pinto S
(2014) Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors. PLoS ONE 9(2):e88908
General
Muise ES, et al.
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Muise ES, Souza S, Chi A, Tan Y, Zhao X, Liu F, Dallas-Yang Q, Wu M, Sarr T, Zhu L, Guo H, Li Z, Li W, Hu W, Jiang G, Paweletz CP, Hendrickson RC, Thompson JR, Mu J, Berger JP, Mehmet H
(2013) Downstream signaling pathways in mouse adipose tissues following acute in vivo administration of fibroblast growth factor 21. PLoS ONE 8(9):e73011
General
Mennes E, et al.
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Mennes E, Dungan CM, Frendo-Cumbo S, Williamson DL, Wright DC
(2014) Aging-associated reductions in lipolytic and mitochondrial proteins in mouse adipose tissue are not rescued by metformin treatment. J. Gerontol. A Biol. Sci. Med. Sci. 69(9):1060-8
General
McLaren DG, et al.
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McLaren DG, Cardasis HL, Stout SJ, Wang SP, Mendoza V, Castro-Perez JM, Miller PL, Murphy BA, Cumiskey AM, Cleary MA, Johns DG, Previs SF, Roddy TP
(2013) Use of [13C18] oleic acid and mass isotopomer distribution analysis to study synthesis of plasma triglycerides in vivo: analytical and experimental considerations. Anal. Chem. 85(13):6287-94
General
McKinney BC, et al.
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McKinney BC, Schneider JS, Schafer GL, Lowing JL, Mohan S, Zhao MX, Heng MY, Albin RL, Seasholtz AF, Akil H, Murphy GG
(2008) Decreased locomotor activity in mice expressing tTA under control of the CaMKII alpha promoter. Genes Brain Behav. 7(2):203-13
General
McCurdy TR, et al.
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McCurdy TR, Patrick AL, Eltringham-Smith LJ, Bhakta V, Sheffield WP, Fox-Robichaud AE
(2014) Alpha-1 acid glycoprotein reduces hepatic leukocyte recruitment in murine models of either early endotoxemia or early sepsis. Microcirculation 21(1):74-83
General
McBrearty BA, et al.
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McBrearty BA, Clark LD, Zhang XM, Blankenhorn EP, Heber-Katz E
(1998) Genetic analysis of a mammalian wound-healing trait. Proc. Natl. Acad. Sci. U.S.A. 95(20):11792-7
General
Lloyd SA, et al.
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Lloyd SA, Bandstra ER, Willey JS, Riffle SE, Tirado-Lee L, Nelson GA, Pecaut MJ, Bateman TA
(2012) Effect of proton irradiation followed by hindlimb unloading on bone in mature mice: a model of long-duration spaceflight. Bone 51(4):756-64
General
Liverani E, et al.
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Liverani E, Rico MC, Garcia AE, Kilpatrick LE, Kunapuli SP
(2013) Prasugrel metabolites inhibit neutrophil functions. J. Pharmacol. Exp. Ther. 344(1):231-43
General
Liu G, et al.
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Liu G, Li Z, Wei Y, Lin Y, Yang C, Liu T
(2014) Direct detection of FoxP3 expression in thymic double-negative CD4-CD8- cells by flow cytometry. Sci Rep 4:5781
General
Little SR, et al.
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Little SR, Lynn DM, Ge Q, Anderson DG, Puram SV, Chen J, Eisen HN, Langer R
(2004) Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proc. Natl. Acad. Sci. U.S.A. 101(26):9534-9
General
Lin SA, et al.
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Lin SA, Patel M, Suresch D, Connolly B, Bao B, Groves K, Rajopadhye M, Peterson JD, Klimas M, Sur C, Bednar B
(2012) Quantitative Longitudinal Imaging of Vascular Inflammation and Treatment by Ezetimibe in apoE Mice by FMT Using New Optical Imaging Biomarkers of Cathepsin Activity and α(v)β(3) Integrin. Int J Mol Imaging 2012:189254
General
Leib DA, et al.
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Leib DA, Machalek MA, Williams BR, Silverman RH, Virgin HW
(2000) Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene. Proc. Natl. Acad. Sci. U.S.A. 97(11):6097-101
General
Lee SN, et al.
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Lee SN, Peng B, Desjardins R, Pintar JE, Day R, Lindberg I
(2007) Strain-specific steroidal control of pituitary function. J. Endocrinol. 192(3):515-25
General
Lee HC, et al.
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Lee HC, Wondimu A, Liu Y, Ma JS, Radoja S, Ladisch S
(2012) Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. J. Immunol. 189(7):3521-7
General
Lebsack TW, et al.
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Lebsack TW, Fa V, Woods CC, Gruener R, Manziello AM, Pecaut MJ, Gridley DS, Stodieck LS, Ferguson VL, Deluca D
(2010) Microarray analysis of spaceflown murine thymus tissue reveals changes in gene expression regulating stress and glucocorticoid receptors. J. Cell. Biochem. 110(2):372-81
General
Lan H, et al.
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Lan H, Lin HV, Wang CF, Wright MJ, Xu S, Kang L, Juhl K, Hedrick JA, Kowalski TJ
(2012) Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways. Br. J. Pharmacol. 165(8):2799-807
General
Krahe TE, et al.
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Krahe TE, Seabrook TA, Chen CK, Fox MA, Guido W
(2012) Modulation of CREB in the dorsal lateral geniculate nucleus of dark-reared mice. Neural Plast. 2012:426437
General
Kohman RE, et al.
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Kohman RE, Han X, Bleier BS
(2014) Heterotopic mucosal engrafting procedure for direct drug delivery to the brain in mice. J Vis Exp (89)
General
Kodandaramaiah SB, et al.
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Kodandaramaiah SB, Franzesi GT, Chow BY, Boyden ES, Forest CR
(2012) Automated whole-cell patch-clamp electrophysiology of neurons in vivo. Nat. Methods 9(6):585-7
General
Købler C, et al.
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Købler C, Saber AT, Jacobsen NR, Wallin H, Vogel U, Qvortrup K, Mølhave K
(2014) FIB-SEM imaging of carbon nanotubes in mouse lung tissue. Anal Bioanal Chem 406(16):3863-73
General
Kim H, et al.
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Kim H, Bernard ME, Flickinger J, Epperly MW, Wang H, Dixon TM, Shields D, Houghton F, Zhang X, Greenberger JS
(2011) The autophagy-inducing drug carbamazepine is a radiation protector and mitigator. Int. J. Radiat. Biol. 87(10):1052-60
General
Kharitonenkov A, et al.
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Kharitonenkov A, Beals JM, Micanovic R, Strifler BA, Rathnachalam R, Wroblewski VJ, Li S, Koester A, Ford AM, Coskun T, Dunbar JD, Cheng CC, Frye CC, Bumol TF, Moller DE
(2013) Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319. PLoS ONE 8(3):e58575
General
Bothe GW, et al.
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Bothe GW, Bolivar VJ, Vedder MJ, Geistfeld JG
(2004) Genetic and behavioral differences among five inbred mouse strains commonly used in the production of transgenic and knockout mice. Genes Brain Behav. 3(3):149-57
Almodovar AJ, et al.
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Almodovar AJ, Luther RJ, Stonebrook CL, Wood PA
(2013) Genomic structure and genetic drift in C57BL/6 congenic metabolic mutant mice. Mol. Genet. Metab. 110(3):396-400
Kawas LH, et al.
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Kawas LH, McCoy AT, Yamamoto BJ, Wright JW, Harding JW
(2012) Development of angiotensin IV analogs as hepatocyte growth factor/Met modifiers. J. Pharmacol. Exp. Ther. 340(3):539-48
General
Kalash R, et al.
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Kalash R, Berhane H, Yang Y, Epperly MW, Wang H, Dixon T, Rhieu B, Greenberger JS, Huq MS
(2014) Improved survival of mice after total body irradiation with 10 MV photon, 2400 MU/min SRS beam. In Vivo 28(1):1-12
General
Kalash R, et al.
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Kalash R, Berhane H, Goff J, Houghton F, Epperly MW, Dixon T, Zhang X, Sprachman MM, Wipf P, Franicola D, Wang H, Greenberger JS
(2013) Effects of thoracic irradiation on pulmonary endothelial compared to alveolar type-II cells in fibrosis-prone C57BL/6NTac mice. In Vivo 27(3):291-7
General
Kaczocha M, et al.
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Kaczocha M, Rebecchi MJ, Ralph BP, Teng YH, Berger WT, Galbavy W, Elmes MW, Glaser ST, Wang L, Rizzo RC, Deutsch DG, Ojima I
(2014) Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. PLoS ONE 9(4):e94200
General
Ivannikov MV, et al.
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Ivannikov MV, Sugimori M, Llinás RR
(2013) Synaptic vesicle exocytosis in hippocampal synaptosomes correlates directly with total mitochondrial volume. J. Mol. Neurosci. 49(1):223-30
General
Huang TT, et al.
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Huang TT, Naeemuddin M, Elchuri S, Yamaguchi M, Kozy HM, Carlson EJ, Epstein CJ
(2006) Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase. Hum. Mol. Genet. 15(7):1187-94
General
Holschneider DP, et al.
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Holschneider DP, Wang Z, Pang RD
(2014) Functional connectivity-based parcellation and connectome of cortical midline structures in the mouse: a perfusion autoradiography study. Front Neuroinform 8:61
General
Heiker JT, et al.
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Heiker JT, Klöting N, Kovacs P, Kuettner EB, Sträter N, Schultz S, Kern M, Stumvoll M, Blüher M, Beck-Sickinger AG
(2013) Vaspin inhibits kallikrein 7 by serpin mechanism. Cell. Mol. Life Sci. 70(14):2569-83
General
Hajrasouliha AR, et al.
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Hajrasouliha AR, Sadrai Z, Lee HK, Chauhan SK, Dana R
(2013) Expression of the chemokine decoy receptor D6 mediates dendritic cell function and promotes corneal allograft rejection. Mol. Vis. 19:2517-25
General
Hajrasouliha AR, et al.
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Hajrasouliha AR, Funaki T, Sadrai Z, Hattori T, Chauhan SK, Dana R
(2012) Vascular endothelial growth factor-C promotes alloimmunity by amplifying antigen-presenting cell maturation and lymphangiogenesis. Invest. Ophthalmol. Vis. Sci. 53(3):1244-50
General
Forman MB, et al.
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Forman MB, Gillespie DG, Cheng D, Jackson EK
(2014) A novel adenosine precursor 2',3'-cyclic adenosine monophosphate inhibits formation of post-surgical adhesions. Dig. Dis. Sci. 59(9):2118-25
General
Ferrari G, et al.
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Ferrari G, Hajrasouliha AR, Sadrai Z, Ueno H, Chauhan SK, Dana R
(2013) Nerves and neovessels inhibit each other in the cornea. Invest. Ophthalmol. Vis. Sci. 54(1):813-20
General
Feng B, et al.
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Feng B, La JH, Tanaka T, Schwartz ES, McMurray TP, Gebhart GF
(2012) Altered colorectal afferent function associated with TNBS-induced visceral hypersensitivity in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 303(7):G817-24
General
Feng B, et al.
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Feng B, La JH, Schwartz ES, Tanaka T, McMurray TP, Gebhart GF
(2012) Long-term sensitization of mechanosensitive and -insensitive afferents in mice with persistent colorectal hypersensitivity. Am. J. Physiol. Gastrointest. Liver Physiol. 302(7):G676-83
General
Feng B, et al.
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Feng B, Kiyatkin ME, La JH, Ge P, Solinga R, Silos-Santiago I, Gebhart GF
(2013) Activation of guanylate cyclase-C attenuates stretch responses and sensitization of mouse colorectal afferents. J. Neurosci. 33(23):9831-9
General
Egan CM, et al.
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Egan CM, Sridhar S, Wigler M, Hall IM
(2007) Recurrent DNA copy number variation in the laboratory mouse. Nat. Genet. 39(11):1384-9
General
Ecoiffier T, et al.
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Ecoiffier T, Yuen D, Chen L
(2010) Differential distribution of blood and lymphatic vessels in the murine cornea. Invest. Ophthalmol. Vis. Sci. 51(5):2436-40
General
Christy AC, et al.
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Christy AC, Byrnes KR, Settle TL
(2014) Evaluation of medicated gel as a supplement to providing acetaminophen in the drinking water of C57BL/6 mice after surgery. J. Am. Assoc. Lab. Anim. Sci. 53(2):180-4
General
Chen H, et al.
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Chen H, Wu S, Lu R, Zhang YG, Zheng Y, Sun J
(2014) Pulmonary permeability assessed by fluorescent-labeled dextran instilled intranasally into mice with LPS-induced acute lung injury. PLoS ONE 9(7):e101925
General
Boutin SR, et al.
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Boutin SR, Shen Z, Roesch PL, Stiefel SM, Sanderson AE, Multari HM, Pridhoko EA, Smith JC, Taylor NS, Lohmiller JJ, Dewhirst FE, Klein HJ, Fox JG
(2010) Helicobacter pullorum outbreak in C57BL/6NTac and C3H/HeNTac barrier-maintained mice. J. Clin. Microbiol. 48(5):1908-10
General
Billaud M, et al.
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Billaud M, Lohman AW, Straub AC, Parpaite T, Johnstone SR, Isakson BE
(2012) Characterization of the thoracodorsal artery: morphology and reactivity. Microcirculation 19(4):360-72
General
Tsiftsoglou SA, et al.
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Tsiftsoglou SA, Sim RB
(2004) Human complement factor I does not require cofactors for cleavage of synthetic substrates. J. Immunol. 173(1):367-75
Experimental Autoimmune Encephalomyelitis (EAE)
Mony JT, et al.
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Mony JT, Khorooshi R, Owens T
(2014) MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE. Mult. Scler. 20(10):1312-21
Experimental Autoimmune Encephalomyelitis (EAE)
Mony JT, et al.
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Mony JT, Khorooshi R, Owens T
(2014) Chemokine receptor expression by inflammatory T cells in EAE. Front Cell Neurosci 8:187
Experimental Autoimmune Encephalomyelitis (EAE)
Isaksson M, et al.
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Isaksson M, Lundgren BA, Ahlgren KM, Kämpe O, Lobell A
(2012) Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE. Eur. J. Immunol. 42(10):2555-63
Experimental Autoimmune Encephalomyelitis (EAE)
Matsuo S, et al.
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Matsuo S, Yang WL, Aziz M, Kameoka S, Wang P
(2014) Fatty acid synthase inhibitor C75 ameliorates experimental colitis. Mol. Med. 20:1-9
Colitis
Hayes CL, et al.
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Hayes CL, Natividad JM, Jury J, Martin R, Langella P, Verdu EF
(2014) Efficacy of Bifidobacterium breve NCC2950 against DSS-induced colitis is dependent on bacterial preparation and timing of administration. Benef Microbes 5(1):79-88
Colitis
Sturm M, et al.
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Sturm M, Becker A, Schroeder A, Bilkei-Gorzo A, Zimmer A
(2015) Effect of chronic corticosterone application on depression-like behavior in C57BL/6N and C57BL/6J mice. Genes Brain Behav. 14(3):292-300
Behavior
Malá H, et al.
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Malá H, Chen Y, Worm VH, Kure J, Kaae BH, Madsen U, Badolo L, Pickering DS, Mogensen J
(2012) Cognitive enhancing effects of an AMPA receptor positive modulator on place learning in mice. Behav. Brain Res. 226(1):18-25
Behavior
Bryant CD, et al.
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Bryant CD, Zhang NN, Sokoloff G, Fanselow MS, Ennes HS, Palmer AA, McRoberts JA
(2008) Behavioral differences among C57BL/6 substrains: implications for transgenic and knockout studies. J. Neurogenet. 22(4):315-31
Behavior
Bourdi M, et al.
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Bourdi M, Davies JS, Pohl LR
(2011) Mispairing C57BL/6 substrains of genetically engineered mice and wild-type controls can lead to confounding results as it did in studies of JNK2 in acetaminophen and concanavalin A liver injury. Chem. Res. Toxicol. 24(6):794-6
Behavior
Bothe GW, et al.
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Bothe GW, Bolivar VJ, Vedder MJ, Geistfeld JG
(2005) Behavioral differences among fourteen inbred mouse strains commonly used as disease models. Comp. Med. 55(4):326-34
Behavior
Ren X, et al.
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Ren X, Lutfy K, Mangubat M, Ferrini MG, Lee ML, Liu Y, Friedman TC
(2013) Alterations in phosphorylated CREB expression in different brain regions following short- and long-term morphine exposure: relationship to food intake. J Obes 2013:764742
Addiction
Mangubat M, et al.
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Mangubat M, Lutfy K, Lee ML, Pulido L, Stout D, Davis R, Shin CS, Shahbazian M, Seasholtz S, Sinha-Hikim A, Sinha-Hikim I, O'Dell LE, Lyzlov A, Liu Y, Friedman TC
(2012) Effect of nicotine on body composition in mice. J. Endocrinol. 212(3):317-26
Addiction
Lim JP, et al.
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Lim JP, Zou ME, Janak PH, Messing RO
(2012) Responses to ethanol in C57BL/6 versus C57BL/6 × 129 hybrid mice. Brain Behav 2(1):22-31
Addiction
Heinla I, et al.
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Heinla I, Leidmaa E, Visnapuu T, Philips MA, Vasar E
(2014) Enrichment and individual housing reinforce the differences in aggressiveness and amphetamine response in 129S6/SvEv and C57BL/6 strains. Behav. Brain Res. 267:66-73
Addiction
Christensen MH, et al.
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Christensen MH, Ishibashi M, Nielsen ML, Leonard CS, Kohlmeier KA
(2014) Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: implications for the heightened adolescent susceptibility to nicotine addiction. Neuropharmacology 85:263-83
Addiction
Chen RZ, et al.
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Chen RZ, Huang RR, Shen CP, MacNeil DJ, Fong TM
(2004) Synergistic effects of cannabinoid inverse agonist AM251 and opioid antagonist nalmefene on food intake in mice. Brain Res. 999(2):227-30
Addiction
Kirchain SM, et al.
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Kirchain SM, Hayward AM, Mkandawire JM, Qi P, Burds AA
(2008) Comparison of tetraploid blastocyst microinjection of outbred Crl:CD1(ICR), hybrid B6D2F1/Tac, and inbred C57BL/6NTac embryos for generation of mice derived from embryonic stem cells. Comp. Med. 58(2):145-50
Stem Cells/Regenerative Medicine/Tissue Engineering
Ihrig M, et al.
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Ihrig M, Whary MT, Dangler CA, Fox JG
(2005) Gastric helicobacter infection induces a Th2 phenotype but does not elevate serum cholesterol in mice lacking inducible nitric oxide synthase. Infect. Immun. 73(3):1664-70
Gastrointestinal, Infectious Disease
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