Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
Full Text |
| Castillo-Carranza DL, et al. Mouse over for full list |
(2015) | Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model. | J Neurosci 35(12):4857-68 | Alzheimer's, Therapeutic Efficacy Evaluation | ||
| Ciccone R, et al. Mouse over for full list |
(2019) | Amyloid β-Induced Upregulation of Na1.6 Underlies Neuronal Hyperactivity in Tg2576 Alzheimer's Disease Mouse Model. | Sci Rep 9(1):13592 | Alzheimer's, Therapeutic Efficacy Evaluation | ||
| Piccialli I, et al. Mouse over for full list |
(2021) | The Na/Ca Exchanger 3 Is Functionally Coupled With the Na1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca Refilling in a Transgenic Model of Alzheimer's Disease. | Front Pharmacol 12:775271 | |||
| Bergamini G, et al. Mouse over for full list |
(2022) | Longitudinal assessment of aggression and circadian rhythms in the APPswe mouse model of Alzheimer`s disease. | Physiol Behav :113787 | |||
| Martín-Moreno AM, et al. Mouse over for full list |
(2012) | Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice. | J Neuroinflammation 9:8 | Targeted transgenic |
Behavior, Alzheimer's | |
| Torcinaro A, et al. Mouse over for full list |
(2021) | Peripheral Nerve Impairment in a Mouse Model of Alzheimer's Disease. | Brain Sci 11(9) | |||
| Sooy K, et al. Mouse over for full list |
(2015) | Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease. | Endocrinology 156(12):4592-603 | |||
| Levenson JM, et al. Mouse over for full list |
(2016) | NPT088 reduces both amyloid-β and tau pathologies in transgenic mice. | Alzheimers Dement (N Y) 2(3):141-155 | |||
| Ishida K, et al. Mouse over for full list |
(2020) | 5-Caffeoylquinic Acid Ameliorates Cognitive Decline and Reduces Aβ Deposition by Modulating Aβ Clearance Pathways in APP/PS2 Transgenic Mice. | Nutrients 12(2) | |||
| Tackenberg C, et al. Mouse over for full list |
(2020) | Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. | PLoS One 15(9):e0239584 | |||
| Salazar JG, et al. Mouse over for full list |
(2021) | Paraoxonase-1 and -3 Protein Expression in the Brain of the Tg2576 Mouse Model of Alzheimer's Disease. | Antioxidants (Basel) 10(3) | Alzheimer's | ||
| Guo HH, et al. Mouse over for full list |
(2021) | Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss. | Bone Res 9(1):31 | |||
| Wiȩckowska-Gacek A, et al. Mouse over for full list |
(2021) | Western Diet Induces Impairment of Liver-Brain Axis Accelerating Neuroinflammation and Amyloid Pathology in Alzheimer's Disease. | Front Aging Neurosci 13:654509 | Alzheimer's | ||
| Wei Z, et al. Mouse over for full list |
(2021) | Brain metabolism in tau and amyloid mouse models of Alzheimer's disease: An MRI study. | NMR Biomed :e4568 | Alzheimer's | ||
| Calvo-Rodriguez M, et al. Mouse over for full list |
(2020) | Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer's disease. | Nat Commun 11(1):2146 | Alzheimer's | ||
| Lee WJ, et al. Mouse over for full list |
(2019) | Possible epigenetic regulatory effect of dysregulated circular RNAs in Alzheimer's disease model. | Sci Rep 9(1):11956 | Alzheimer's | ||
| Snellman A, et al. Mouse over for full list |
(2019) | Effect of genotype and age on cerebral [18F]FDG uptake varies between transgenic APPSWE-PS1dE9 and Tg2576 mouse models of Alzheimer's disease. | Sci Rep 9(1):5700 | Alzheimer's | ||
| Zhang C, et al. Mouse over for full list |
(2018) | Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis. | Sci Rep 8(1):1144 | Alzheimer's | ||
| Fryer JD, et al. Mouse over for full list |
(2005) | Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model. | J. Neurosci. 25(11):2803-10 | Alzheimer's | ||
| Arbel-Ornath M, et al. Mouse over for full list |
(2017) | Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain. | Mol Neurodegener 12(1):27 | |||
| Rustay NR, et al. Mouse over for full list |
(2010) | Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease. | Brain Res. 1311:136-47 | |||
| Wolf A, et al. Mouse over for full list |
(2016) | A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice. | PLoS ONE 11(1):e0147733 | Neuroscience | ||
| Hsiao K, et al. Mouse over for full list |
(1996) | Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. | Science 274(5284):99-102 | |||
| Sevigny J, et al. Mouse over for full list |
(2016) | The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. | Nature 537(7618):50-6 | Alzheimer's | ||
| Yao Y, et al. Mouse over for full list |
(2004) | Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis. | J Neuroinflammation 1(1):21 | Alzheimer's | ||
| Urbanc B, et al. Mouse over for full list |
(2002) | Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease. | Proc. Natl. Acad. Sci. U.S.A. 99(22):13990-5 | Alzheimer's | ||
| Stobart MJ, et al. Mouse over for full list |
(2007) | Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease. | Mol Neurodegener 2:5 | |||
| Spires TL, et al. Mouse over for full list |
(2005) | Transgenic models of Alzheimer's disease: learning from animals. | NeuroRx 2(3):423-37 | Alzheimer's | ||
| Skovronsky DM, et al. Mouse over for full list |
(2000) | In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. | Proc. Natl. Acad. Sci. U.S.A. 97(13):7609-14 | Alzheimer's | ||
| Puglielli L, et al. Mouse over for full list |
(2005) | Alzheimer disease beta-amyloid activity mimics cholesterol oxidase. | J. Clin. Invest. 115(9):2556-63 | Alzheimer's | ||
| Poduslo JF, et al. Mouse over for full list |
(2001) | Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease. | Neurobiol. Dis. 8(4):555-67 | Alzheimer's | ||
| Norris CM, et al. Mouse over for full list |
(2005) | Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. | J. Neurosci. 25(18):4649-58 | Alzheimer's | ||
| Niwa K, et al. Mouse over for full list |
(2000) | Abeta 1-40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation. | Proc. Natl. Acad. Sci. U.S.A. 97(17):9735-40 | Alzheimer's | ||
| McGowan E, et al. Mouse over for full list |
(2005) | Abeta42 is essential for parenchymal and vascular amyloid deposition in mice. | Neuron 47(2):191-9 | Alzheimer's | ||
| Loeffler DA Mouse over for full list |
(2004) | Using animal models to determine the significance of complement activation in Alzheimer's disease. | J Neuroinflammation 1(1):18 | Alzheimer's | ||
| Li Q, et al. Mouse over for full list |
(2004) | Overcoming antigen masking of anti-amyloidbeta antibodies reveals breaking of B cell tolerance by virus-like particles in amyloidbeta immunized amyloid precursor protein transgenic mice. | BMC Neurosci 5:21 | T And/Or B Cell Function | ||
| Lee JY, et al. Mouse over for full list |
(2002) | Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. | Proc. Natl. Acad. Sci. U.S.A. 99(11):7705-10 | Alzheimer's | ||
| Kelly BL, et al. Mouse over for full list |
(2005) | Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. | J. Biol. Chem. 280(36):31746-53 | Alzheimer's | ||
| Frautschy SA, et al. Mouse over for full list |
(1998) | Microglial response to amyloid plaques in APPsw transgenic mice. | Am. J. Pathol. 152(1):307-17 | Alzheimer's | ||
| Eriksen JL, et al. Mouse over for full list |
(2003) | NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo. | J. Clin. Invest. 112(3):440-9 | Alzheimer's | ||
| Dong H, et al. Mouse over for full list |
(2005) | Acetylcholinesterase inhibitors ameliorate behavioral deficits in the Tg2576 mouse model of Alzheimer's disease. | Psychopharmacology (Berl.) 181(1):145-52 | Alzheimer's | ||
| Chapman PF, et al. Mouse over for full list |
(1999) | Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. | Nat. Neurosci. 2(3):271-6 | Alzheimer's | ||
| Chang KA, et al. Mouse over for full list |
(2006) | Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration. | Mol. Cell. Biol. 26(11):4327-38 |
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