APPSWE - Model 1349 Publications

APPSWE - Model 1349 Model Page

Filter publications by application: All Alzheimer's T And/Or B Cell Function
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Arbel-Ornath M, et al.
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Arbel-Ornath M, Hudry E, Boivin JR, Hashimoto T, Takeda S, Kuchibhotla KV, Hou S, Lattarulo CR, Belcher AM, Shakerdge N, Trujillo PB, Muzikansky A, Betensky RA, Hyman BT, Bacskai BJ
(2017) Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain. Mol Neurodegener 12(1):27
Hsiao K, et al.
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Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G
(1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274(5284):99-102
Sevigny J, et al.
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Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, Brennan MS, Quintero-Monzon O, Scannevin RH, Arnold HM, Engber T, Rhodes K, Ferrero J, Hang Y, Mikulskis A, Grimm J, Hock C, Nitsch RM, Sandrock A
(2016) The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. Nature 537(7618):50-6
Alzheimer's
Yao Y, et al.
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Yao Y, Chinnici C, Tang H, Trojanowski JQ, Lee VM, Praticò D
(2004) Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis. J Neuroinflammation 1(1):21
Alzheimer's
Urbanc B, et al.
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Urbanc B, Cruz L, Le R, Sanders J, Ashe KH, Duff K, Stanley HE, Irizarry MC, Hyman BT
(2002) Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 99(22):13990-5
Alzheimer's
Stobart MJ, et al.
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Stobart MJ, Parchaliuk D, Simon SL, Lemaistre J, Lazar J, Rubenstein R, Knox JD
(2007) Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease. Mol Neurodegener 2:5
Spires TL, et al.
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Spires TL, Hyman BT
(2005) Transgenic models of Alzheimer's disease: learning from animals. NeuroRx 2(3):423-37
Alzheimer's
Skovronsky DM, et al.
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Skovronsky DM, Zhang B, Kung MP, Kung HF, Trojanowski JQ, Lee VM
(2000) In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 97(13):7609-14
Alzheimer's
Puglielli L, et al.
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Puglielli L, Friedlich AL, Setchell KD, Nagano S, Opazo C, Cherny RA, Barnham KJ, Wade JD, Melov S, Kovacs DM, Bush AI
(2005) Alzheimer disease beta-amyloid activity mimics cholesterol oxidase. J. Clin. Invest. 115(9):2556-63
Alzheimer's
Poduslo JF, et al.
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Poduslo JF, Curran GL, Wengenack TM, Malester B, Duff K
(2001) Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease. Neurobiol. Dis. 8(4):555-67
Alzheimer's
Norris CM, et al.
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Norris CM, Kadish I, Blalock EM, Chen KC, Thibault V, Porter NM, Landfield PW, Kraner SD
(2005) Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. J. Neurosci. 25(18):4649-58
Alzheimer's
Niwa K, et al.
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Niwa K, Younkin L, Ebeling C, Turner SK, Westaway D, Younkin S, Ashe KH, Carlson GA, Iadecola C
(2000) Abeta 1-40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation. Proc. Natl. Acad. Sci. U.S.A. 97(17):9735-40
Alzheimer's
McGowan E, et al.
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McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, Delucia M, Lin WL, Dolios G, Wang R, Eckman CB, Dickson DW, Hutton M, Hardy J, Golde T
(2005) Abeta42 is essential for parenchymal and vascular amyloid deposition in mice. Neuron 47(2):191-9
Alzheimer's
Loeffler DA
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Loeffler DA
(2004) Using animal models to determine the significance of complement activation in Alzheimer's disease. J Neuroinflammation 1(1):18
Alzheimer's
Li Q, et al.
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Li Q, Cao C, Chackerian B, Schiller J, Gordon M, Ugen KE, Morgan D
(2004) Overcoming antigen masking of anti-amyloidbeta antibodies reveals breaking of B cell tolerance by virus-like particles in amyloidbeta immunized amyloid precursor protein transgenic mice. BMC Neurosci 5:21
T And/Or B Cell Function
Lee JY, et al.
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Lee JY, Cole TB, Palmiter RD, Suh SW, Koh JY
(2002) Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. Proc. Natl. Acad. Sci. U.S.A. 99(11):7705-10
Alzheimer's
Kelly BL, et al.
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Kelly BL, Vassar R, Ferreira A
(2005) Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. J. Biol. Chem. 280(36):31746-53
Alzheimer's
Frautschy SA, et al.
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Frautschy SA, Yang F, Irrizarry M, Hyman B, Saido TC, Hsiao K, Cole GM
(1998) Microglial response to amyloid plaques in APPsw transgenic mice. Am. J. Pathol. 152(1):307-17
Alzheimer's
Eriksen JL, et al.
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Eriksen JL, Sagi SA, Smith TE, Weggen S, Das P, McLendon DC, Ozols VV, Jessing KW, Zavitz KH, Koo EH, Golde TE
(2003) NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo. J. Clin. Invest. 112(3):440-9
Alzheimer's
Dong H, et al.
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Dong H, Csernansky CA, Martin MV, Bertchume A, Vallera D, Csernansky JG
(2005) Acetylcholinesterase inhibitors ameliorate behavioral deficits in the Tg2576 mouse model of Alzheimer's disease. Psychopharmacology (Berl.) 181(1):145-52
Alzheimer's
Chapman PF, et al.
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Chapman PF, White GL, Jones MW, Cooper-Blacketer D, Marshall VJ, Irizarry M, Younkin L, Good MA, Bliss TV, Hyman BT, Younkin SG, Hsiao KK
(1999) Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat. Neurosci. 2(3):271-6
Alzheimer's
Chang KA, et al.
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Chang KA, Kim HS, Ha TY, Ha JW, Shin KY, Jeong YH, Lee JP, Park CH, Kim S, Baik TK, Suh YH
(2006) Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration. Mol. Cell. Biol. 26(11):4327-38