APOE3 Publications

APOE3 Model Page

Filter publications by application: All Alzheimer's Cardiovascular Diabetes (Type 2) Metabolism Neuroscience
Filter publications by model type: All Humanization Knock in



Paper Title


Model Type


Full Text

Toro CA, et al.
Mouse over for full list
Toro CA, Hansen J, Siddiq MM, Johnson K, Zhao W, Azulai D, Das DK, Bauman W, Sebra R, Cai D, Iyengar R, Cardozo CP
(2021) The Human ApoE4 Variant Reduces Functional Recovery and Neuronal Sprouting After Incomplete Spinal Cord Injury in Male Mice. Front Cell Neurosci 15:626192
Schmitt J, et al.
Mouse over for full list
Schmitt J, Paradis AL, Boucher M, Andrieu L, Barnéoud P, Rondi-Reig L
(2021) Flexibility as a marker of early cognitive decline in humanized apolipoprotein E ε4 (ApoE4) mice. Neurobiol Aging 102:129-138
Shang Y, et al.
Mouse over for full list
Shang Y, Mishra A, Wang T, Wang Y, Desai M, Chen S, Mao Z, Do L, Bernstein AS, Trouard TP, Brinton RD
(2020) Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice. PLoS ONE 15(1):e0225392
Caberlotto L, et al.
Mouse over for full list
Caberlotto L, Nguyen TP, Lauria M, Priami C, Rimondini R, Maioli S, Cedazo-Minguez A, Sita G, Morroni F, Corsi M, Carboni L
(2019) Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases. Sci Rep 9(1):3965
Alzheimer's, Diabetes (Type 2)
Wu L, et al.
Mouse over for full list
Wu L, Zhang X, Zhao L
(2018) Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention. J. Neurosci.
Salomon-Zimri S, et al.
Mouse over for full list
Salomon-Zimri S, Glat MJ, Barhum Y, Luz I, Boehm-Cagan A, Liraz O, Ben-Zur T, Offen D, Michaelson DM
(2016) Reversal of ApoE4-Driven Brain Pathology by Vascular Endothelial Growth Factor Treatment. J. Alzheimers Dis. 53(4):1443-58
Knock in, Humanization
Cardiovascular, Metabolism, Neuroscience, Alzheimer's
Sullivan PM, et al.
Mouse over for full list
Sullivan PM, Mezdour H, Aratani Y, Knouff C, Najib J, Reddick RL, Quarfordt SH, Maeda N
(1997) Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. J. Biol. Chem. 272(29):17972-80
Malek G, et al.
Mouse over for full list
Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Bowes Rickman C
(2005) Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proc. Natl. Acad. Sci. U.S.A. 102(33):11900-5
Knouff C, et al.
Mouse over for full list
Knouff C, Hinsdale ME, Mezdour H, Altenburg MK, Watanabe M, Quarfordt SH, Sullivan PM, Maeda N
(1999) Apo E structure determines VLDL clearance and atherosclerosis risk in mice. J. Clin. Invest. 103(11):1579-86
Sullivan PM, et al.
Mouse over for full list
Sullivan PM, Mezdour H, Quarfordt SH, Maeda N
(1998) Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2. J. Clin. Invest. 102(1):130-5
Burgos JS, et al.
Mouse over for full list
Burgos JS, Ramirez C, Sastre I, Valdivieso F
(2006) Effect of apolipoprotein E on the cerebral load of latent herpes simplex virus type 1 DNA. J. Virol. 80(11):5383-7

Welcome! Tell us a little about yourself