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Piedrahita JA, et al.
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Piedrahita JA, Zhang SH, Hagaman JR, Oliver PM, Maeda N
(1992) Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 89(10):4471-5
Stem Cells/Regenerative Medicine/Tissue Engineering
Zhang SH, et al.
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Zhang SH, Reddick RL, Avdievich E, Surles LK, Jones RG, Reynolds JB, Quarfordt SH, Maeda N
(1997) Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice. J. Clin. Invest. 99(12):2858-66
Zhang SH, et al.
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Zhang SH, Reddick RL, Burkey B, Maeda N
(1994) Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption. J. Clin. Invest. 94(3):937-45
Yuan H, et al.
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Yuan H, Wong LS, Bhattacharya M, Ma C, Zafarani M, Yao M, Schneider M, Pitas RE, Martins-Green M
(2007) The effects of second-hand smoke on biological processes important in atherogenesis. BMC Cardiovasc Disord 7:1
Sullivan PM, et al.
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Sullivan PM, Mezdour H, Quarfordt SH, Maeda N
(1998) Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2. J. Clin. Invest. 102(1):130-5
Shibata M, et al.
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Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, Holtzman DM, Miller CA, Strickland DK, Ghiso J, Zlokovic BV
(2000) Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J. Clin. Invest. 106(12):1489-99
Pászty C, et al.
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Pászty C, Maeda N, Verstuyft J, Rubin EM
(1994) Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. J. Clin. Invest. 94(2):899-903
Maezawa I, et al.
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Maezawa I, Maeda N, Montine TJ, Montine KS
(2006) Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice. J Neuroinflammation 3:10
Lippmann M, et al.
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Lippmann M, Ito K, Hwang JS, Maciejczyk P, Chen LC
(2006) Cardiovascular effects of nickel in ambient air. Environ. Health Perspect. 114(11):1662-9
Knowles JW, et al.
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Knowles JW, Reddick RL, Jennette JC, Shesely EG, Smithies O, Maeda N
(2000) Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment. J. Clin. Invest. 105(4):451-8
Ishibashi S, et al.
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Ishibashi S, Herz J, Maeda N, Goldstein JL, Brown MS
(1994) The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proc. Natl. Acad. Sci. U.S.A. 91(10):4431-5
Burgos JS, et al.
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Burgos JS, Ramirez C, Sastre I, Valdivieso F
(2006) Effect of apolipoprotein E on the cerebral load of latent herpes simplex virus type 1 DNA. J. Virol. 80(11):5383-7
Alzheimer's
Aihara K, et al.
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Aihara K, Azuma H, Akaike M, Ikeda Y, Sata M, Takamori N, Yagi S, Iwase T, Sumitomo Y, Kawano H, Yamada T, Fukuda T, Matsumoto T, Sekine K, Sato T, Nakamichi Y, Yamamoto Y, Yoshimura K, Watanabe T, Nakamura T, Oomizu A, Tsukada M, Hayashi H, Sudo T, Kato S, Matsumoto T
(2007) Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II-deficient mice. J. Clin. Invest. 117(6):1514-26