BALB/cA Bom

Origin:

The BALB/cABom inbred model was developed by the Chester Beatty Institute. The Cancer Research Institute in Aarhus, Denmark received stock from the Chester Beatty Institute in 1956. M&B A/S (now Taconic Europe) received stock at F35 + 15 in 1968. Fibiger Laboratory in Copenhagen (Fib) received stock at F50 + 9 in 1972. M&B A/S (now Taconic Europe) received stock at F95 from Fib in 1988. The Taconic foundation colony was at F95 + 31 in 2000.

Availability:

Genetics:

• Strain Profile: Akp1^b, Akp2^a, Anpep^b, Car2^b, Es1^b, Es2^b, Es3^a, Es5^b, Es9^a, H6pd1^b, Gpi1^a, Got2^b, Hbb^d, Idh1^a, Ldr1^a, Ldr2^a, Mod1^a, Mup1^a, Pep3^a, Pgm1^a, Trf^b
• Immunology: H2^d

Coat Color Loci:

Color:

Species:

Animal Diet:

n= 40 per sex at MPF health standard from EU production colonies. Data collected 2014-15.
High and Low represent mean +/- 1 standard deviation.
Based on sample size the charts above represents ~60% of the population.
All growth curves represent animals housed in our barriers, at our standard density and fed NIH31-M diet. Variations at customer facilities will alter expected growth curves. Growth charts are provided only as a guide, if a specific weight criteria is needed please order animals by weight.

Average litter size: 7

• Pathophysiology: Low tumor rate in the absence of MMTV. High incidence in the presence of MMTV. Susceptible to streptozotocin-induced and encephalomycarditis (EMC-M) induced diabetes. High incidence of spontaneous calcified heart lesions in older animals. High incidence of spleen amyloidosis in older males. Very sensitive to radiation.