Agrp - Model 7975 - KO

Constitutive Knockout

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CALL: 888.822.6642 + 45 70 23 04 05 (EUROPE)

This line is cryopreserved and requires cryorecovery.

C57BL/6 Background

Model #
Genotype
Nomenclature

7975

B6.Cg-Agrp^tm1Sqn

Model Description

Gene Family:

Neuropeptide

Genetic Background:

C57BL/6

Gene Symbol:

Agrp

Gene Accession Number:

NM_007427

Allele Type:

Source:

Merck Research Laboratories

Availability:

Cryopreserved at Taconic

Species:

Mouse

Official Gene Name:

agouti related protein

Initial Publication:

Chen HY, Trumbauer ME, Chen AS, Weingarth DT, Adams JR, Frazier EG, Shen Z, Marsh DJ, Feighner SD, Gaun XM, Nargund RP, Smith RG, Van der Ploeg LH, Howard AD, MacNeil DJ, Qian S. Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein. Endocrinology 2004 Jun; 145(6):2607-12.

Alleles

See H.Y. Chen et al, Endocrinology 145: 2607-2612, 2004 for details on how this GEM model has been generated.

Licensing

Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.

The GEM Collection Commercial and Academic Terms of Sale grant perpetual use rights.

Deliverables

GEM Collection models exist as cryopreserved materials. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Customers will receive:

A minimum of four (4) mice mutant for the selected mutation. In rare cases where the cryopreserved material also contains a recombinase gene, this may be reduced to 1-2 mutant mice.
Validated genotyping protocols
Animal health report. Mice will meet Taconic's Murine Pathogen Free™ (MPF™) health standard.

Please note that in rare instances (2%) cryorecovery may prove to be difficult, either extending timeline or ultimately successful recovery.

For Profit Pricing:

Price per Line ($)
$30,000

Nonprofit Pricing:

Price per Line ($)
$5,500

For Profit Pricing:

Price per Line (€)
€27,300

Nonprofit Pricing:

Price per Line (€)
€5,005