About the webinar:
This webinar discusses the advantages of utilizing Taconic Biosciences' huNOG-EXL EA option for research studies.
The huNOG-EXL is a versatile humanized immune system mouse that supports the development of lymphoid and myeloid cells. The new huNOG-EXL EA option allows more flexibility in study design, particularly for specific challenging scenarios.
During this webinar, you’ll understand how inter- and intra-donor variability can impact experimental outcomes and how Taconic controls for these in humanized mice production.
The huNOG-EXL EA model can:
- Maximize the possible study window for huNOG-EXL mice
- Provide a sufficient study window for efficacy studies using slow-growing tumors or with more prolonged treatment paradigms
- Allow for the start of experimentation in huNOG-EXL mice before emergence of T cells or during the peak B cell period
- Functional implications of murine Fc gamma receptors in humanized immune system mice on the evaluation of efficacy and pharmacodynamic indicators for antibody-based drugs
- Overcome unavoidable logistics and quarantine challenges, which may reduce the study window unacceptably when using the standard huNOG-EXL offering
