About the webinar:
Humanized immune system (HIS) mice are invaluable for advancing preclinical research, with various models available to support lymphoid, myeloid and/or specific cell populations. T and NK cells are popular targets for immuno-oncology cell therapies, as well as for immune-modulating drugs, and specialized host strains expressing relevant human cytokines are widely used in efficacy studies involving these cell populations. The hIL-2 NOG and hIL-15 NOG models allow for enhanced T cell and natural killer (NK) cell engraftment, enabling more sophisticated studies related to graft vs. host disease or immuno-oncology.
This webinar will focus on the applications of both the hIL-2 NOG for TIL and CAR-T therapies, as well as the hIL-15 NOG for NK cell research, including NK cell therapies and NK cell-modulating drugs. This webinar is part three of a webinar series - click here to explore the full educational series.
View this webinar to:
- How 2nd generation NOG strains expressing relevant human cytokines can support engraftment of specific cell populations such as T and NK cells
- How to select the most appropriate host strain and donor cells for your experimental needs
- How hIL-2 NOG and hIL-15 NOG mice can be used to support drug discovery and advance cell-based therapies
- Which HIS model is right for you, based on your immune cell population of interest