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Filter publications by application: All Immunology Infectious Disease Melanoma T And/Or B Cell Function
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Zhu Y, et al.
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Zhu Y, Sánchez-Tacuba L, Hou G, Kawagishi T, Feng N, Greenberg HB, Ding S
(2022) A recombinant murine-like rotavirus with Nano-Luciferase expression reveals tissue tropism, replication dynamics, and virus transmission. Front Immunol 13:911024
Milligan JC, et al.
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Milligan JC, Davis CW, Yu X, Ilinykh PA, Huang K, Halfmann PJ, Cross RW, Borisevich V, Agans KN, Geisbert JB, Chennareddy C, Goff AJ, Piper AE, Hui S, Shaffer KCL, Buck T, Heinrich ML, Branco LM, Crozier I, Holbrook MR, Kuhn JH, Kawaoka Y, Glass PJ, Bukreyev A, Geisbert TW, Worwa G, Ahmed R, Saphire EO
(2022) Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell 185(6):995-1007.e18
Kwock JT, et al.
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Kwock JT, Handfield C, Suwanpradid J, Hoang P, McFadden MJ, Labagnara KF, Floyd L, Shannon J, Uppala R, Sarkar MK, Gudjonsson JE, Corcoran DL, Lazear HM, Sempowski G, Horner SM, MacLeod AS
(2020) IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection. Sci Adv 6(14):eaay3245
Brenner E, et al.
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Brenner E, Schörg BF, Ahmetlić F, Wieder T, Hilke FJ, Simon N, Schroeder C, Demidov G, Riedel T, Fehrenbacher B, Schaller M, Forschner A, Eigentler T, Niessner H, Sinnberg T, Böhm KS, Hömberg N, Braumüller H, Dauch D, Zwirner S, Zender L, Sonanini D, Geishauser A, Bauer J, Eichner M, Jarick KJ, Beilhack A, Biskup S, Döcker D, Schadendorf D, Quintanilla-Martinez L, Pichler BJ, Kneilling M, Mocikat R, Röcken M
(2020) Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours. Nat Commun 11(1):1335
T And/Or B Cell Function, Melanoma
Mumphrey SM, et al.
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Mumphrey SM, Changotra H, Moore TN, Heimann-Nichols ER, Wobus CE, Reilly MJ, Moghadamfalahi M, Shukla D, Karst SM
(2007) Murine norovirus 1 infection is associated with histopathological changes in immunocompetent hosts, but clinical disease is prevented by STAT1-dependent interferon responses. J. Virol. 81(7):3251-63
Infectious Disease
McFadden N, et al.
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McFadden N, Bailey D, Carrara G, Benson A, Chaudhry Y, Shortland A, Heeney J, Yarovinsky F, Simmonds P, Macdonald A, Goodfellow I
(2011) Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4. PLoS Pathog. 7(12):e1002413
Infectious Disease
Coleman CM, et al.
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Coleman CM, Matthews KL, Goicochea L, Frieman MB
(2014) Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus. J. Gen. Virol. 95(Pt 2):408-412
Infectious Disease
Zornetzer GA, et al.
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Zornetzer GA, Frieman MB, Rosenzweig E, Korth MJ, Page C, Baric RS, Katze MG
(2010) Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection. J. Virol. 84(21):11297-309
Infectious Disease
Hogan RJ, et al.
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Hogan RJ, Gao G, Rowe T, Bell P, Flieder D, Paragas J, Kobinger GP, Wivel NA, Crystal RG, Boyer J, Feldmann H, Voss TG, Wilson JM
(2004) Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1. J. Virol. 78(20):11416-21
Infectious Disease
Graham RL, et al.
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Graham RL, Becker MM, Eckerle LD, Bolles M, Denison MR, Baric RS
(2012) A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease. Nat. Med. 18(12):1820-6
Infectious Disease
Frieman MB, et al.
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Frieman MB, Chen J, Morrison TE, Whitmore A, Funkhouser W, Ward JM, Lamirande EW, Roberts A, Heise M, Subbarao K, Baric RS
(2010) SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism. PLoS Pathog. 6(4):e1000849
Infectious Disease
Rodriguez SE, et al.
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Rodriguez SE, Cross RW, Fenton KA, Bente DA, Mire CE, Geisbert TW
(2019) Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever. Sci Rep 9(1):7755
Infectious Disease
Hsu CC, et al.
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Hsu CC, Meeker SM, Escobar S, Brabb TL, Paik J, Park H, Iritani BM, Maggio-Price L
(2018) Murine norovirus inhibits B cell development in the bone marrow of STAT1-deficient mice. Virology 515:123-133
Infectious Disease
Karwacz K, et al.
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Karwacz K, Miraldi ER, Pokrovskii M, Madi A, Yosef N, Wortman I, Chen X, Watters A, Carriero N, Awasthi A, Regev A, Bonneau R, Littman D, Kuchroo VK
(2017) Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation. Nat. Immunol. 18(4):412-421
Meraz MA, et al.
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Meraz MA, White JM, Sheehan KC, Bach EA, Rodig SJ, Dighe AS, Kaplan DH, Riley JK, Greenlund AC, Campbell D, Carver-Moore K, DuBois RN, Clark R, Aguet M, Schreiber RD
(1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84(3):431-42
Wobus CE, et al.
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Wobus CE, Karst SM, Thackray LB, Chang KO, Sosnovtsev SV, Belliot G, Krug A, Mackenzie JM, Green KY, Virgin HW
(2004) Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages. PLoS Biol. 2(12):e432
Infectious Disease
Wang J, et al.
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Wang J, Schreiber RD, Campbell IL
(2002) STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-alpha in the central nervous system. Proc. Natl. Acad. Sci. U.S.A. 99(25):16209-14
Walters DM, et al.
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Walters DM, Antao-Menezes A, Ingram JL, Rice AB, Nyska A, Tani Y, Kleeberger SR, Bonner JC
(2005) Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis. Am. J. Pathol. 167(5):1221-9
Pasieka TJ, et al.
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Pasieka TJ, Collins L, O'Connor MA, Chen Y, Parker ZM, Berwin BL, Piwnica-Worms DR, Leib DA
(2011) Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice. PLoS ONE 6(9):e24018
Infectious Disease
Nishibori T, et al.
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Nishibori T, Tanabe Y, Su L, David M
(2004) Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease. J. Exp. Med. 199(1):25-34
Mullarky IK, et al.
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Mullarky IK, Szaba FM, Berggren KN, Kummer LW, Wilhelm LB, Parent MA, Johnson LL, Smiley ST
(2006) Tumor necrosis factor alpha and gamma interferon, but not hemorrhage or pathogen burden, dictate levels of protective fibrin deposition during infection. Infect. Immun. 74(2):1181-8
Lugo-Villarino G, et al.
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Lugo-Villarino G, Maldonado-Lopez R, Possemato R, Penaranda C, Glimcher LH
(2003) T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 100(13):7749-54
Lucas S, et al.
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Lucas S, Ghilardi N, Li J, de Sauvage FJ
(2003) IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. U.S.A. 100(25):15047-52
T And/Or B Cell Function
Loke P, et al.
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Loke P, Allison JP
(2003) PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells. Proc. Natl. Acad. Sci. U.S.A. 100(9):5336-41
Lighvani AA, et al.
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Lighvani AA, Frucht DM, Jankovic D, Yamane H, Aliberti J, Hissong BD, Nguyen BV, Gadina M, Sher A, Paul WE, O'Shea JJ
(2001) T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proc. Natl. Acad. Sci. U.S.A. 98(26):15137-42
Kotelkin A, et al.
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Kotelkin A, Belyakov IM, Yang L, Berzofsky JA, Collins PL, Bukreyev A
(2006) The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response. J. Virol. 80(12):5958-67
Hancock WW, et al.
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Hancock WW, Szaba FM, Berggren KN, Parent MA, Mullarky IK, Pearl J, Cooper AM, Ely KH, Woodland DL, Kim IJ, Blackman MA, Johnson LL, Smiley ST
(2004) Intact type 1 immunity and immune-associated coagulative responses in mice lacking IFN gamma-inducible fibrinogen-like protein 2. Proc. Natl. Acad. Sci. U.S.A. 101(9):3005-10
Halford WP, et al.
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Halford WP, Weisend C, Grace J, Soboleski M, Carr DJ, Balliet JW, Imai Y, Margolis TP, Gebhardt BM
(2006) ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virol. J. 3:44
Halford WP, et al.
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Halford WP, Maender JL, Gebhardt BM
(2005) Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1. Virol. J. 2:56
Gongora R, et al.
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Gongora R, Stephan RP, Schreiber RD, Cooper MD
(2000) Stat-1 is not essential for inhibition of B lymphopoiesis by type I IFNs. J. Immunol. 165(5):2362-6
Gavrilescu LC, et al.
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Gavrilescu LC, Butcher BA, Del Rio L, Taylor GA, Denkers EY
(2004) STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection. Infect. Immun. 72(3):1257-64
Durbin JE, et al.
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Durbin JE, Hackenmiller R, Simon MC, Levy DE
(1996) Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84(3):443-50
Collazo CM, et al.
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Collazo CM, Yap GS, Hieny S, Caspar P, Feng CG, Taylor GA, Sher A
(2002) The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments. Infect. Immun. 70(12):6933-9
Chin YE, et al.
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Chin YE, Kitagawa M, Su WC, You ZH, Iwamoto Y, Fu XY
(1996) Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 272(5262):719-22
Agrawal S, et al.
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Agrawal S, Agarwal ML, Chatterjee-Kishore M, Stark GR, Chisolm GM
(2002) Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis. Mol. Cell. Biol. 22(7):1981-92
Lugo-Villarino G, et al.
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Lugo-Villarino G, Ito S, Klinman DM, Glimcher LH
(2005) The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 102(37):13248-53

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