Stat1 Publications

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Karwacz K, et al.
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Karwacz K, Miraldi ER, Pokrovskii M, Madi A, Yosef N, Wortman I, Chen X, Watters A, Carriero N, Awasthi A, Regev A, Bonneau R, Littman D, Kuchroo VK
(2017) Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation. Nat. Immunol. 18(4):412-421
Immunology
Meraz MA, et al.
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Meraz MA, White JM, Sheehan KC, Bach EA, Rodig SJ, Dighe AS, Kaplan DH, Riley JK, Greenlund AC, Campbell D, Carver-Moore K, DuBois RN, Clark R, Aguet M, Schreiber RD
(1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84(3):431-42
Wobus CE, et al.
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Wobus CE, Karst SM, Thackray LB, Chang KO, Sosnovtsev SV, Belliot G, Krug A, Mackenzie JM, Green KY, Virgin HW
(2004) Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages. PLoS Biol. 2(12):e432
Wang J, et al.
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Wang J, Schreiber RD, Campbell IL
(2002) STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-alpha in the central nervous system. Proc. Natl. Acad. Sci. U.S.A. 99(25):16209-14
Walters DM, et al.
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Walters DM, Antao-Menezes A, Ingram JL, Rice AB, Nyska A, Tani Y, Kleeberger SR, Bonner JC
(2005) Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis. Am. J. Pathol. 167(5):1221-9
Pasieka TJ, et al.
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Pasieka TJ, Collins L, O'Connor MA, Chen Y, Parker ZM, Berwin BL, Piwnica-Worms DR, Leib DA
(2011) Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice. PLoS ONE 6(9):e24018
Nishibori T, et al.
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Nishibori T, Tanabe Y, Su L, David M
(2004) Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease. J. Exp. Med. 199(1):25-34
Mullarky IK, et al.
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Mullarky IK, Szaba FM, Berggren KN, Kummer LW, Wilhelm LB, Parent MA, Johnson LL, Smiley ST
(2006) Tumor necrosis factor alpha and gamma interferon, but not hemorrhage or pathogen burden, dictate levels of protective fibrin deposition during infection. Infect. Immun. 74(2):1181-8
Lugo-Villarino G, et al.
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Lugo-Villarino G, Maldonado-Lopez R, Possemato R, Penaranda C, Glimcher LH
(2003) T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 100(13):7749-54
Lucas S, et al.
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Lucas S, Ghilardi N, Li J, de Sauvage FJ
(2003) IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. U.S.A. 100(25):15047-52
T And/Or B Cell Function
Loke P, et al.
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Loke P, Allison JP
(2003) PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells. Proc. Natl. Acad. Sci. U.S.A. 100(9):5336-41
Lighvani AA, et al.
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Lighvani AA, Frucht DM, Jankovic D, Yamane H, Aliberti J, Hissong BD, Nguyen BV, Gadina M, Sher A, Paul WE, O'Shea JJ
(2001) T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proc. Natl. Acad. Sci. U.S.A. 98(26):15137-42
Kotelkin A, et al.
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Kotelkin A, Belyakov IM, Yang L, Berzofsky JA, Collins PL, Bukreyev A
(2006) The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response. J. Virol. 80(12):5958-67
Hancock WW, et al.
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Hancock WW, Szaba FM, Berggren KN, Parent MA, Mullarky IK, Pearl J, Cooper AM, Ely KH, Woodland DL, Kim IJ, Blackman MA, Johnson LL, Smiley ST
(2004) Intact type 1 immunity and immune-associated coagulative responses in mice lacking IFN gamma-inducible fibrinogen-like protein 2. Proc. Natl. Acad. Sci. U.S.A. 101(9):3005-10
Halford WP, et al.
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Halford WP, Weisend C, Grace J, Soboleski M, Carr DJ, Balliet JW, Imai Y, Margolis TP, Gebhardt BM
(2006) ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virol. J. 3:44
Halford WP, et al.
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Halford WP, Maender JL, Gebhardt BM
(2005) Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1. Virol. J. 2:56
Gongora R, et al.
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Gongora R, Stephan RP, Schreiber RD, Cooper MD
(2000) Stat-1 is not essential for inhibition of B lymphopoiesis by type I IFNs. J. Immunol. 165(5):2362-6
Gavrilescu LC, et al.
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Gavrilescu LC, Butcher BA, Del Rio L, Taylor GA, Denkers EY
(2004) STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection. Infect. Immun. 72(3):1257-64
Durbin JE, et al.
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Durbin JE, Hackenmiller R, Simon MC, Levy DE
(1996) Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84(3):443-50
Collazo CM, et al.
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Collazo CM, Yap GS, Hieny S, Caspar P, Feng CG, Taylor GA, Sher A
(2002) The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments. Infect. Immun. 70(12):6933-9
Chin YE, et al.
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Chin YE, Kitagawa M, Su WC, You ZH, Iwamoto Y, Fu XY
(1996) Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 272(5262):719-22
Agrawal S, et al.
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Agrawal S, Agarwal ML, Chatterjee-Kishore M, Stark GR, Chisolm GM
(2002) Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis. Mol. Cell. Biol. 22(7):1981-92
Lugo-Villarino G, et al.
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Lugo-Villarino G, Ito S, Klinman DM, Glimcher LH
(2005) The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 102(37):13248-53