Human 15q13.3 Deletion [Df(h15q13)/+] Mouse Publications

Human 15q13.3 Deletion [Df(h15q13)/+] Mouse Model Page

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Forsingdal A, et al.
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Forsingdal A, Fejgin K, Nielsen V, Werge T, Nielsen J
(2016) 15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes. Transl Psychiatry 6(7):e860
Behavior, Neuroscience
Thelin J, et al.
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Thelin J, Halje P, Nielsen J, Didriksen M, Petersson P, Bastlund JF
(2016) The translationally relevant mouse model of the 15q13.3 microdeletion syndrome reveals deficits in neuronal spike firing matching clinical neurophysiological biomarkers seen in schizophrenia. Acta Physiol (Oxf)
Behavior, Neuroscience
Nilsson SR, et al.
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Nilsson SR, Celada P, Fejgin K, Thelin J, Nielsen J, Santana N, Heath CJ, Larsen PH, Nielsen V, Kent BA, Saksida LM, Stensbøl TB, Robbins TW, Bastlund JF, Bussey TJ, Artigas F, Didriksen M
(2016) A mouse model of the 15q13.3 microdeletion syndrome shows prefrontal neurophysiological dysfunctions and attentional impairment. Psychopharmacology (Berl.) 233(11):2151-63
Gass N, et al.
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Gass N, Weber-Fahr W, Sartorius A, Becker R, Didriksen M, Stensbøl TB, Bastlund JF, Meyer-Lindenberg A, Schwarz AJ
(2016) An acetylcholine alpha7 positive allosteric modulator rescues a schizophrenia-associated brain endophenotype in the 15q13.3 microdeletion, encompassing CHRNA7. Eur Neuropsychopharmacol 26(7):1150-60
Behavior
Fejgin K, et al.
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Fejgin K, Nielsen J, Birknow MR, Bastlund JF, Nielsen V, Lauridsen JB, Stefansson H, Steinberg S, Sorensen HB, Mortensen TE, Larsen PH, Klewe IV, Rasmussen SV, Stefansson K, Werge TM, Kallunki P, Christensen KV, Didriksen M
(2014) A mouse model that recapitulates cardinal features of the 15q13.3 microdeletion syndrome including schizophrenia- and epilepsy-related alterations. Biol. Psychiatry 76(2):128-37
Behavior