| Model No. | Nomenclature | Genotype |
|---|---|---|
| SHR | NTac:SHR |
Spontaneously Hypertensive
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Overview
Nomenclature: NTac:SHR
- Derived from the Okamoto-Aoki Strain
- Males exhibit average systolic blood pressures greater than 200 mmHg by 3-4 months of age
- The SHR is generally used for studies in hypertension and cardiovascular research
- Based on historical usage, the SHR has outbred nomenclature NTac:SHR. However, genetic testing has shown that this colony is homozygous at all alleles tested (inbred). Taconic maintains the SHR through random breeding in a closed colony.
Origin
Genetics
Guides & Publications
Applications & Therapeutic Areas
- Cardiovascular Disease
Transit, Housing & Welfare
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Diet
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Data
Average litter size: 7
n= 200 per sex at the MPF health standard from US colonies. Data collected 2008-12.
High and Low represent mean +/- 2 standard deviations.
Based on sample size the charts above represents ~95% of the population.
All growth curves represent animals housed in our barriers, at our standard density and fed NIH31-M diet. Variations at customer facilities will alter expected growth curves. Growth charts are provided only as a guide, if a specific weight criteria is needed please order animals by weight.
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