| Model No. | Nomenclature | Genotype |
|---|---|---|
| 1005 | B6.SJL-Tg(PLA2G2A)703 N?+16 | Inquire for genotype |
sPLA2
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Overview
Nomenclature: B6.SJL-Tg(PLA2G2A)703 N?+16
- Carries transgene for human Group II Phospholipase A2
- Develops alopecia, epidermal hyperplasia and enlarged sebacious glands
- Exhibits an increased susceptibility to LPS induced shock and atherosclerosis
- Useful to identify and evaluate new drug candidates for treatement of human inflammatory conditions and atherosclerosis.
Origin
This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.
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Genetics
Guides & Publications
Initial Publication: Grass, D.S., Felkner, R.H., Chiang, M., Wallace, R.E., Nevalainen, T.J., Bennett, C.F., Swanson, M.E. Expression of Human Group II PLA2 in Transgenic Mice Results in Epidermal Hyperplasia in the Absence of Inflammatory Infiltrate, J Clin Invest., Vol. 97, No. 10, May 1996, pp. 2233-2241.
Transit, Housing & Welfare
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Diet
- Licensing
- Pricing - USD
- Pricing - EUR
- Select my Health Standard
- Get Custom Pricing Guide
sPLA2
Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.
This model is sold under terms which grant perpetual use rights.
This model is sold under terms which grant perpetual use rights.
Pricing - USD
1005
| Item | Commercial | Nonprofit |
|---|---|---|
| Cryopreserved Model | $23,100.00 | $17,325.00 |
Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.
Fees for Taconic Transit Cages™ and freight are in addition to the price above.
Pricing - EUR
1005
| Item | Commercial | Nonprofit |
|---|---|---|
| Cryopreserved Model | €21.000,00 | €15.855,00 |
Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.
Fees for Taconic Transit Cages™ and freight are in addition to the price above.
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