| Model No. | Nomenclature | Genotype |
|---|---|---|
| 13075 | B6.129-Tg(Pdgfrb-cre)9Rha | Inquire for genotype |
Pdgfrb-Cre Mouse
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- Price & Licensing
- Overview
- Genetics
- Guides & Publications
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Overview
Nomenclature: B6.129-Tg(Pdgfrb-cre)9Rha
- Tissue specific cre deleter
- Expresses cre recombinase under the control of the Pdgfrb promoter
- Permits cre recombination in pericytes and smooth vascular muscle cells
- May be useful for angiogenesis studies
Availability
This model is available for immediate cryorecovery.Origin
The Pdgfrb-Cre Mouse was developed in the laboratory of Ralf Adams at the London Research Institute. The model was generated by microinjecting a transgene containing a genomic Pdgfrb promoter fragment fused to cre recombinase and a polyA sequence, into 129/B6 zygotes. Founder lines were maintained on a mixed 129;B6 background. Taconic received embryos from CRT in 2013.
Source: Sponsor: Cancer Research Technology
This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.
Taconic’s Colony Management experts can design a plan to grow your colony faster.
Genetics
Guides & Publications
Initial Publication:
Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N, Lindblom P, Shani M, Zicha D, Adams RH. (2006) Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 124(1):161-73.
Applications & Therapeutic Areas
- Oncology & Immuno-Oncology
- Recombinase-mediated Gene Deletion
Transit, Housing & Welfare
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- Licensing
- Pricing - USD
- Pricing - EUR
- Select my Health Standard
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Pdgfrb-Cre Mouse
Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.
This model is sold under terms which grant perpetual use rights.
This model is sold under terms which grant perpetual use rights.
Pricing - USD
13075
| Item | Commercial | Nonprofit |
|---|---|---|
| Cryopreserved Model | $23,100.00 | $14,700.00 |
Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.
Fees for Taconic Transit Cages™ and freight are in addition to the price above.
Pricing - EUR
13075
| Item | Commercial | Nonprofit |
|---|---|---|
| Cryopreserved Model | €21.000,00 | €13.125,00 |
Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.
Fees for Taconic Transit Cages™ and freight are in addition to the price above.
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