Mir34a - Model 9743 - KO

  • Cryopreserved
  • Mouse
  • Not available for direct purchase by CRO
Model No.NomenclatureGenotype
9743C57BL/6-Mir34atm1.2 Mrl
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Overview

Nomenclature: C57BL/6-Mir34atm1.2 Mrl

  • The targeting vector has been generated using C57BL/6J DNA and transfected into C57BL/6NTac ES cell line.
  • Mir34a sequence has been flanked by LoxP sites.
  • The constitutive KO allele has been generated after Cre-mediatedrecombination by crossing chimeras to a Cre-Deleter on a C57BL/6 background.
  • The constitutive KO line has been subsequently backcrossed to C57BL/6NTac animals for at least 2 generations and the Cre-transgene was removed by segregation.
  • The remaining recombination sites are located in non-conserved regions of the genome.
  • Datamining and Design performed in 2008.

Source: TaconicArtemis

This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.

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Genetics

Species:Mouse
Strain Type:Inbred
Allele Type:Constitutive Knockout
Genetic Background:C57BL/6
Gene Family: microRNA
Gene Symbol: Mir34a
Gene Accession Number: NR_029751
Gene Name: microRNA 34a

9743 WT

1842 cKO

9743 KO

key-allele.jpg

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Mir34a - Model 9743 - KO

Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.

The GEM Collection Commercial and Academic Terms of Sale grant perpetual use rights.

    ItemCommercialNonprofit
    Cryopreserved Model$32,500$5,500
      ItemCommercialNonprofit
      Cryopreserved Model€29.500€5.005

       

      Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.

      Fees for Taconic Transit Cages™ and freight are in addition to the price above.

       

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