Ggt1 - Model 9554 - TG

  • Cryopreserved
  • Mouse
  • Not available for direct purchase by CRO
Model No.NomenclatureGenotype
9554C57BL/6-Tg(Alb-GGT1)93 Mrl
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Overview

Nomenclature: C57BL/6-Tg(Alb-GGT1)93 Mrl

  • The transgenic construct contains 5´ the serum albumin enhancer (822bp) and promoter (194bp), the human GGT1 cDNA, additional Kozak consensus sequence, and SV40 polyA signal at 3´ end.
  • The NotI linearized transgenic construct was microinjected in C57BL6 mice by pronuclear injection.
  • Putative transgenic founders were identified by genotyping and bred for germ line transmission with C57BL6 mice.
  • Heterozygous transgenic mice were identified by genotyping.
    • Line 9556, M135-188, has highest expression level of transgene in the liver.
    • Line 9555, M135-53, has second highest expression level of the transgene in the liver.
    • Line 9557, M135-161, has third highest expression level of the transgene in the liver.
    • Line 9554, M135-93, has lowest expression level of the transgene in the liver.
  • Datamining and Design performed in 2006.

Availability

Cryopreserved at Taconic

Source: Institut Clinique de la Souris (ICS), Illkirch, France

This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.

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Genetics

Species:Mouse
Strain Type:Inbred
Allele Type:Random Transgenic
Genetic Background:C57BL/6
Gene Family: Transferase
Gene Symbol: Ggt1
Gene Accession Number: NM_008116
Gene Name:  gamma-glutamyltransferase 1

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Guides & Publications

Transit, Housing & Welfare

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Ggt1 - Model 9554 - TG

Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.

The GEM Collection Commercial and Academic Terms of Sale grant perpetual use rights.

    ItemCommercialNonprofit
    Cryopreserved Model$32,500$5,500
      ItemCommercialNonprofit
      Cryopreserved Model€29.500€5.005

       

      Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.

      Fees for Taconic Transit Cages™ and freight are in addition to the price above.

       

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