Fads2 - Model 10685 - TTG

  • Cryopreserved
  • Mouse
  • Not available for direct purchase by CRO
  • GEM Collection
Model No.NomenclatureGenotype
10685C57BL/6-Gt(ROSA)26Sortm1 mrlInquire for genotype
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Overview

Nomenclature: C57BL/6-Gt(ROSA)26Sortm1 mrl

  • The targeting vector has been transfected into the TaconicArtemis C57BL/6NTac ES cell line.
  • The following elements have been inserted into the ROSA26 locus:

    • A CAG promoter cassette (containing a cytomegalovirus early enhancer element, a chicken beta-actin promoter and an adenovirus intron).
    • The Fads2 open reading frame (based on NCBI transcript NM_019699_1).
    • A synthetic polyadenylation signal.
    • A Neomycin resistance (NeoR) cassette containing a polyadenylation signal and lacking a translation initiation codon.

  • The constitutive TTG line has been generated by crossing chimeras to C57BL/6NTac animals.
  • The FADS2 protein is expressed under the control of the CAG promoter.
  • The presence of the NeoR cassette terminates the transcription from the ROSA26 promoter.
  • Datamining and Design performed in 2009.

Availability

Cryopreserved at Taconic

Source: TaconicArtemis

This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 12 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.

Taconic’s Colony Management experts can design a plan to grow your colony faster.

Genetics

Species:Mouse
Strain Type:Inbred
Allele Type:Targeted Transgenic
Genetic Background:C57BL/6
Gene Family: Desaturase
Gene Symbol: Fads2
Gene Accession Number: NM_019699.1
Gene Name:  fatty acid desaturase 2

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Guides & Publications

Transit, Housing & Welfare

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Fads2 - Model 10685 - TTG

Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.

The GEM Collection Commercial and Academic/Non-Profit Terms of Sale grant perpetual use rights.

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USD

    ItemCommercialNonprofit
    Cryopreserved Model$21,000$5,500

     

    *If you choose to breed this model at Taconic, you are eligible for a 20% discount on the Commercial repository model price as outlined below.

    ItemCommercialNonprofit
    Cryopreserved Model$16,800$5,500

    Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.

    Fees for Taconic Transit Cages™ and freight are in addition to the price above.

    EUR

    ItemCommercialNonprofit
    Cryopreserved Model€21.000€5.005

    *If you choose to breed this model at Taconic, you are eligible for a 20% discount on the Commercial repository model price as outlined below.

    ItemCommercial (with 20% breeding discount)Nonprofit
    Cryopreserved Model€16.800€5.005

    Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.

    Fees for Taconic Transit Cages™ and freight are in addition to the price above.

     

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