Creg1 - Model 13787 - KO

  • Cryopreserved
  • Mouse
  • Not available for direct purchase by CRO
Model No.NomenclatureGenotype
13787C57BL/6-Creg1tm1.1Mrl
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Overview

Nomenclature: C57BL/6-Creg1tm1.1Mrl

  • The targeting vector has been generated using C57BL/6J DNA and transfected into Taconic's C57BL/6N Tac ES cell line.
  • Creg1 exon 1 contains the translation initiation codon.
  • Exon 1has been flanked by loxP sites including the FRT site flanked neomycin resistance gene cassette.
  • The neomycin resistance gene cassette has been removed by transient transfection of Flp recombinase into targeted ES cell clones.
  • The conditional KO line has been derived using C57BL/6NTac animals.
  • The constitutive KO allele can be generated by Cre-mediated recombination.
  • Deletion of exon 1 should result in loss of function of the Creg1 gene.
  • The remaining recombination sites are located in non-conserved regions of the genome.
  • Datamining and Design performed in 2009.

Availability

Cryopreserved at Taconic

Source: Xenogen

This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.

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Genetics

Species:Mouse
Strain Type:Inbred
Allele Type:Constitutive Knockout
Genetic Background:C57BL/6
Gene Family: Repressor
Gene Symbol: Creg1
Gene Accession Number: NM_011804
Gene Name: cellular repressor of E1A-stimulated genes 1

13787 creg1 cko

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Creg1 - Model 13787 - KO

Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.

The GEM Collection Commercial and Academic Terms of Sale grant perpetual use rights.

    ItemCommercialNonprofit
    Cryopreserved Model$32,500$5,500
      ItemCommercialNonprofit
      Cryopreserved Model€29.500€5.005

       

      Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.

      Fees for Taconic Transit Cages™ and freight are in addition to the price above.

       

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