Ccr5 Knockout

Ccr5 Knockout Constitutive Knockout Mouse Model
  • Cryopreserved
  • Mouse
  • Black
  • Not available for direct purchase by CRO
Model No.NomenclatureGenotype
3737B6.129P2-Ccr5tm1Kuz N10
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Overview

Nomenclature: B6.129P2-Ccr5tm1Kuz N10

  • Disruption of the Ccr5 gene results in altered immune responses
  • The CC chemokine receptor 5 (CCR5) is the main chemokine receptor for HIV-1 in humans
  • Useful for studies of infectious diseases including HIV-1, malaria, influenza and fungal infections as well as autoimmune disorders

This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.

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Genetics

Species:Mouse
Strain Type:Congenic
Allele Type:Constitutive Knockout
Coat Color:Black
Genetic Background:C57BL/6

Guides & Publications

Initial Publication: 

Huffnagle GB, McNeil LK, McDonald RA, Murphy JW, Toews GB, Maeda N, Kuziel WA. Cutting edge: Role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans. J Immunol. 1999, 163(9):4642-6.

Transit, Housing & Welfare

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Ccr5 Knockout

Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.
This model is sold under terms which grant perpetual use rights.

Pricing - USD

3737

ItemCommercialNonprofit
Cryopreserved Model$23,100.00$17,325.00

Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.

Fees for Taconic Transit Cages™ and freight are in addition to the price above.

Pricing - EUR

3737

ItemCommercialNonprofit
Cryopreserved Model€21.000,00€15.855,00

Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.

Fees for Taconic Transit Cages™ and freight are in addition to the price above.

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2024 Pricing Guide Now Available

Get your Taconic Biosciences 2024 Pricing Guide today. Personalized, customizable, links to up-to-date health reports, and additional information on Taconic's products and services.