The targeting vector has been generated using C57BL/6J DNA and transfected into TaconicArtemis C57BL/6NTac ES cell line.
Exon 2 contains the translation initiation codon.
Exons 5 to 8 have been flanked by loxP sites (size of loxP-flanked region: 2.7 kb).
The constitutive KO allele has been generated after Cre-mediated recombination by crossing chimeras to a Cre-Deleter on a C57BL/6 background.
The constitutive KO line has been derived using C57BL/6NTac animals and the Cre-transgene was removed by segregation.
The corresponding conditional KO allele is available as line 10632.
Datamining and Design performed in 2008.
Gene Family: Transcription Factor
Genetic Background: C57BL/6
Gene Symbol: Psrc1
Gene Accession Number: NM_019976.2
Allele Type: KO
Availability: Cryopreserved at Taconic
Official Gene Name: proline/ serine-rich coiled-coil 1