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The targeting vector has been generated using C57BL/6J DNA and transfected into TaconicArtemis C57BL/6NTac ES cell line.
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Exon 2 contains the translation initiation codon.
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Exons 5 to 8 have been flanked by loxP sites (size of loxP-flanked region: 2.7 kb).
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The conditional KO allele has been generated after Flp-mediated recombination by crossing chimeras to a Flp-Deleter on a C57BL/6 background.
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The conditional KO line has been derived using C57BL/6NTac animals and the Flp-transgene was removed by segregation.
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The constitutive KO allele can be generated by Cre-mediated recombination.
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The corresponding constitutive KO allele is available as line 10217.
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Datamining and Design performed in 2008.
Gene Family:
Transcription factor Genetic Background:
C57BL/6 Gene Symbol:
Psrc1 Gene Accession Number:
NM_001190161 Allele Type:
cKO Source:
TaconicArtemis Availability:
Cryopreserved at Taconic
Species:
Mouse Official Gene Name:
proline/serine-rich coiled-coil 1
