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Gpr119 - Model 10057 - Tg

Microinjected

Cryopreserved Model
This line is cryopreserved and requires cryorecovery.

C57BL/6 Background

  • Model #
  • Genotype
  • Nomenclature
  • 10057
    C57BL/6-Tg(GPR119)10 Mrl
  • A plasmid containing the Mouse Insulin-1 promoter and the human GPR119 cDNA has been engineered.
  • The plasmid construct was microinjected in C57BL6 mice by pronuclear injection.
  • Putative transgenic founders were identified by genotyping and bred for germ line transmission with C57BL6 mice.
  • Heterozygous transgenic mice were identified by genotyping.
  • Line 10057, C57BL/6-Tg(GPR119)10 Mrl, shows an expression of the BAC transgene in the pancreas, the brain and the liver.
  • Line 10056, C57BL/6-Tg(GPR119)6 Mrl, shows an expression of the BAC transgene in the pancreas and the brain.
  • Data mining and Design performed in 2008.

Gene Family:

G-protein coupled receptor

Genetic Background:

C57BL/6

Gene Symbol:

Gpr119

Gene Accession Number:

NM_181751

Allele Type:

Tg

Source:

MCI bred at Taconic

Species:

Mouse

Official Gene Name:

G-protein coupled receptor 119

Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO. The GEM Collection Commercial and Academic Terms of Sale grant perpetual use rights.
GEM Collection models exist as cryopreserved materials. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Customers will receive:

  • A minimum of four (4) mice heterozygous for the selected mutation. In rare cases where the cryopreserved material also contains a recombinase gene, this may be reduced to 1-2 heterozygous mice.
  • Validated genotyping protocols
  • Animal health report. Mice will meet Taconic's Murine Pathogen Free™ (MPF™) health standard.

Please note that in rare instances (2%) cryorecovery may prove to be difficult, either extending timeline or ultimately successful recovery.

For-Profit Pricing:

Price per Line ($)
$30,000

Non-Profit Pricing:

Price per Line ($)
$5,500

For-Profit Pricing:

Price per Line (€)
€27,300

Non-Profit Pricing:

Price per Line (€)
€5,005