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Gpbar1 - Model 11695 - KO

Cryopreserved Model
This line is cryopreserved and requires cryorecovery.

C57BL/6 Background

  • Model #
  • Genotype
  • Nomenclature
  • 11695
    Gpbar1tm1Gvas

Gene Family:

G-protein coupled receptor

Gene Symbol:

Gpbar1

Gene Accession Number:

NM_174985

Allele Type:

KO

Source:

Merck Research Laboratories

Species:

Mouse

Official Gene Name:

G protein-coupled bile acid receptor 1

Initial Publication:

Vassileva G, Golovko A, Markowitz L, Abbondanzo SJ, Zeng M, Yang S, Hoos L, Tetzloff G, Levitan D, Murgolo NJ, Keane K, Davis HR Jr, Hedrick J, Gustafson EL., Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation. Biochem J. 2006 Sep 15;398(3):423-30


See Vassileva G, et al., Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation. Biochem J. 2006 Sep 15;398(3):423-30 for details on how this GEM model has been generated.
Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO. The GEM Collection Commercial and Academic Terms of Sale grant perpetual use rights.
GEM Collection models exist as cryopreserved materials. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Customers will receive:

  • A minimum of four (4) mice heterozygous for the selected mutation. In rare cases where the cryopreserved material also contains a recombinase gene, this may be reduced to 1-2 heterozygous mice.
  • Validated genotyping protocols
  • Animal health report. Mice will meet Taconic's Murine Pathogen Free™ (MPF™) health standard.

Please note that in rare instances (2%) cryorecovery may prove to be difficult, either extending timeline or ultimately successful recovery.

For-Profit Pricing:

Price per Line ($)
$30,000

Non-Profit Pricing:

Price per Line ($)
$5,500

For-Profit Pricing:

Price per Line (€)
€27,300

Non-Profit Pricing:

Price per Line (€)
€5,005