Note: This is a double KO line: Line 11165 contains both the Fabp5 KO.
- The targeting vector has been generated using C57BL/6J DNA and transfected into Taconic’s C57BL/6N Tac ES cell line.
- Fabp5 exon 1 contains the translation initiation codon.
- Exons 1 to 4 have been replaced by the FRT site flanked neomycin resistance gene cassette.
- The neomycin resistance gene cassette has been removed by transient transfection of Flp recombinase into targeted ES cell clones.
- The constitutive KO line has been derived using C57BL/6NTac animals.
- Deletion of exons 1 to 4 should result in loss of function of the Fabp5 gene by removing the entire coding sequence.
- The remaining recombination sites are located in non-conserved regions of the genome.
- Datamining and Design performed in 2008.
Gene Family:
Enzyme activator Genetic Background:
C57BL/6 Gene Symbol:
Fabp4&5 Gene Accession Number:
NM_010634 Allele Type:
dKO Source:
Xenogen Availability:
Cryopreserved at Taconic
Species:
Mouse Official Gene Name:
fatty acid binding protein 5, epidermal
