Tlr3

Constitutive Knockout

Cryopreserved Model
This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • TF3422
    Inquire
    MGI:2156367
Gene Description: toll-like receptor 3

Gene Family:

Membrane

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_126166

Mutation Type:

Targeted

Species:

Mouse

Initial Publication:

http://www.ncbi.nlm.nih.gov/pubmed/11607032
http://www.ncbi.nlm.nih.gov/pubmed/12202403
http://www.ncbi.nlm.nih.gov/pubmed/12466851
http://www.ncbi.nlm.nih.gov/pubmed/14625548
http://www.ncbi.nlm.nih.gov/pubmed/14993594
http://www.ncbi.nlm.nih.gov/pubmed/15110521
http://www.ncbi.nlm.nih.gov/pubmed/15100310
http://www.ncbi.nlm.nih.gov/pubmed/15128790
http://www.ncbi.nlm.nih.gov/pubmed/15210814
http://www.ncbi.nlm.nih.gov/pubmed/15634897
http://www.ncbi.nlm.nih.gov/pubmed/16027240
http://www.ncbi.nlm.nih.gov/pubmed/16105838
http://www.ncbi.nlm.nih.gov/pubmed/16546102
http://www.ncbi.nlm.nih.gov/pubmed/12054664
http://www.ncbi.nlm.nih.gov/pubmed/16782847
http://www.ncbi.nlm.nih.gov/pubmed/17008311
http://www.ncbi.nlm.nih.gov/pubmed/16301743
http://www.ncbi.nlm.nih.gov/pubmed/16210631
http://www.ncbi.nlm.nih.gov/pubmed/16237098
http://www.ncbi.nlm.nih.gov/pubmed/16272328
http://www.ncbi.nlm.nih.gov/pubmed/16936008
http://www.ncbi.nlm.nih.gov/pubmed/17638914
http://www.ncbi.nlm.nih.gov/pubmed/17573354
http://www.ncbi.nlm.nih.gov/pubmed/17572686
http://www.ncbi.nlm.nih.gov/pubmed/17705137
http://www.ncbi.nlm.nih.gov/pubmed/17502662
http://www.ncbi.nlm.nih.gov/pubmed/16424225
http://www.ncbi.nlm.nih.gov/pubmed/18032677
http://www.ncbi.nlm.nih.gov/pubmed/17981792
http://www.ncbi.nlm.nih.gov/pubmed/16456008
http://www.ncbi.nlm.nih.gov/pubmed/16517751
http://www.ncbi.nlm.nih.gov/pubmed/18097050
http://www.ncbi.nlm.nih.gov/pubmed/16368889
http://www.ncbi.nlm.nih.gov/pubmed/18295350
http://www.ncbi.nlm.nih.gov/pubmed/18354215
http://www.ncbi.nlm.nih.gov/pubmed/18368052
http://www.ncbi.nlm.nih.gov/pubmed/17347473
http://www.ncbi.nlm.nih.gov/pubmed/18223009
http://www.ncbi.nlm.nih.gov/pubmed/17049055
http://www.ncbi.nlm.nih.gov/pubmed/18490751
http://www.ncbi.nlm.nih.gov/pubmed/16453294
http://www.ncbi.nlm.nih.gov/pubmed/12855817
http://www.ncbi.nlm.nih.gov/pubmed/15240691
http://www.ncbi.nlm.nih.gov/pubmed/15711573
http://www.ncbi.nlm.nih.gov/pubmed/15558055
http://www.ncbi.nlm.nih.gov/pubmed/16141072
http://www.ncbi.nlm.nih.gov/pubmed/16260493
http://www.ncbi.nlm.nih.gov/pubmed/16244651
http://www.ncbi.nlm.nih.gov/pubmed/16714379
http://www.ncbi.nlm.nih.gov/pubmed/16001129
http://www.ncbi.nlm.nih.gov/pubmed/16369915
http://www.ncbi.nlm.nih.gov/pubmed/12133979
http://www.ncbi.nlm.nih.gov/pubmed/17190817
http://www.ncbi.nlm.nih.gov/pubmed/17456769
http://www.ncbi.nlm.nih.gov/pubmed/17992263
http://www.ncbi.nlm.nih.gov/pubmed/18057004
http://www.ncbi.nlm.nih.gov/pubmed/18322244
http://www.ncbi.nlm.nih.gov/pubmed/14976262
http://www.ncbi.nlm.nih.gov/pubmed/15064760
http://www.ncbi.nlm.nih.gov/pubmed/16886064
http://www.ncbi.nlm.nih.gov/pubmed/16142239
http://www.ncbi.nlm.nih.gov/pubmed/12960379

 


The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyrc-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyrc-Brd background.

For standard orders clients will receive:

  • A minimum of four (4) Mutant Mice, heterozygous for the Selected Mutation, including at least one (1) breeding pair on a mixed 129S5;B6 background.
  • Validated genotyping protocols
  • Animal health data
Business TypePrice per LinePrice per Line for Comprehensive Phenotype Data
For Profit (Commercial)$20,000*
€17,000*
$10,000*
€8,500*
Nonprofit$15,000*
€12,750*
$8,000*
€6,800*
Basic Phenotype Package: $5,000 (€4,200)

KOR models are invoiced upon shipment. Once orders are placed, full purchase price will be applied if order is cancelled.

Fees for Taconic Transit Cages and freight are in addition to the price above.