Klrk1

Constitutive Knockout

Cryopreserved Model
This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • TF3357
    Inquire
    MGI:1196250
Gene Description: killer cell lectin-like receptor subfamily K, member 1

Synonyms: D6H12S2489E, Nkg2d, NKG2-D

Gene Family:

Membrane

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_033078

Mutation Type:

Targeted

Species:

Mouse

Initial Publication:

http://www.ncbi.nlm.nih.gov/pubmed/9464811
http://www.ncbi.nlm.nih.gov/pubmed/9600963
http://www.ncbi.nlm.nih.gov/pubmed/10438936
http://www.ncbi.nlm.nih.gov/pubmed/10464175
http://www.ncbi.nlm.nih.gov/pubmed/10860661
http://www.ncbi.nlm.nih.gov/pubmed/10601355
http://www.ncbi.nlm.nih.gov/pubmed/12150888
http://www.ncbi.nlm.nih.gov/pubmed/12426564
http://www.ncbi.nlm.nih.gov/pubmed/12645935
http://www.ncbi.nlm.nih.gov/pubmed/14523385
http://www.ncbi.nlm.nih.gov/pubmed/14764662
http://www.ncbi.nlm.nih.gov/pubmed/15238421
http://www.ncbi.nlm.nih.gov/pubmed/15328154
http://www.ncbi.nlm.nih.gov/pubmed/15746162
http://www.ncbi.nlm.nih.gov/pubmed/16116470
http://www.ncbi.nlm.nih.gov/pubmed/16002667
http://www.ncbi.nlm.nih.gov/pubmed/16470377
http://www.ncbi.nlm.nih.gov/pubmed/16973387
http://www.ncbi.nlm.nih.gov/pubmed/16914326
http://www.ncbi.nlm.nih.gov/pubmed/16619285
http://www.ncbi.nlm.nih.gov/pubmed/17548517
http://www.ncbi.nlm.nih.gov/pubmed/18209064
http://www.ncbi.nlm.nih.gov/pubmed/18198346
http://www.ncbi.nlm.nih.gov/pubmed/14707119
http://www.ncbi.nlm.nih.gov/pubmed/16141072
http://www.ncbi.nlm.nih.gov/pubmed/15878887
http://www.ncbi.nlm.nih.gov/pubmed/16116168
http://www.ncbi.nlm.nih.gov/pubmed/16323246
http://www.ncbi.nlm.nih.gov/pubmed/17463084
http://www.ncbi.nlm.nih.gov/pubmed/16086018
http://www.ncbi.nlm.nih.gov/pubmed/17952078
http://www.ncbi.nlm.nih.gov/pubmed/18394936
http://www.ncbi.nlm.nih.gov/pubmed/16623599

 


The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyrc-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyrc-Brd background.

For standard orders clients will receive:

  • A minimum of four (4) Mutant Mice, heterozygous for the Selected Mutation, including at least one (1) breeding pair on a mixed 129S5;B6 background.
  • Validated genotyping protocols
  • Animal health data
Business TypePrice per LinePrice per Line for Comprehensive Phenotype Data
For Profit (Commercial)$20,000*
€17,000*
$10,000*
€8,500*
Nonprofit$15,000*
€12,750*
$8,000*
€6,800*
Basic Phenotype Package: $5,000 (€4,200)
*A 10% discount will be applied if the model is bred and managed by Taconic's team of breeding experts.
*A 10% discount will be applied to the purchase of more than one line per fiscal year.

KOR models are invoiced upon shipment. Once orders are placed, full purchase price will be applied if order is cancelled.

Fees for Taconic Transit Cages and freight are in addition to the price above.