Adam33

Gene Family:

Protease

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_033615

Mutation Type:

Targeted

Species:

Mouse

Initial Publication:

http://www.ncbi.nlm.nih.gov/pubmed/10086356
http://www.ncbi.nlm.nih.gov/pubmed/11814695
http://www.ncbi.nlm.nih.gov/pubmed/12466851
http://www.ncbi.nlm.nih.gov/pubmed/15063736
http://www.ncbi.nlm.nih.gov/pubmed/12972401
http://www.ncbi.nlm.nih.gov/pubmed/15657107
http://www.ncbi.nlm.nih.gov/pubmed/11897009
http://www.ncbi.nlm.nih.gov/pubmed/16141072
http://www.ncbi.nlm.nih.gov/pubmed/16079176
http://www.ncbi.nlm.nih.gov/pubmed/16943435
http://www.ncbi.nlm.nih.gov/pubmed/12110844

The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyr^c-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyr^c-Brd background.