Commonly referred to as B6 | Also known as: B6NTac, C57BL/6, Black 6, C57
Black 6 (B6)—C57BL/6NTac Mouse Model
The Black 6 (B6) mouse model is one of the most reliable and consistent inbred strains used in biomedical research. Known for its uniform genetic makeup, the C57BL/6 strain is ideal for researchers who require highly reproducible results across experiments. Whether you’re exploring drug efficacy, genetic disorders, or disease pathways, this strain provides the consistency that modern research demands.
| Model No. | Nomenclature | Genotype |
|---|---|---|
| B6-F | C57BL/6NTac | |
| B6-M | C57BL/6NTac |
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- Description
- Related Products & Services
- Data
- Growth Chart
- Price & Licensing
- Health Report
- Overview
- Genetics
- Guides & Publications
- Applications & Therapeutic Areas
- Transit, Housing & Welfare
- Diet
- Pregnant Mice and Rats Policy
Overview of Black 6 Mouse
Nomenclature: C57BL/6NTac
Taconic's B6 Provides Superior Performance
One of the most used inbred mouse models, the C57BL/6 is used in nearly every research application, and it's commonly used as the genetic background for transgenic mouse models. It is also the preferred model for studying diet-induced obesity and the chronic experimental autoimmune encephalomyelitis model of multiple sclerosis.
- Popular research applications include oncology, immunology, metabolic disease, addiction and toxicology
- C57BL/6NTac is the preferred C57BL/6 substrain for generation of genetically engineered models, including by the Knockout Mouse Project (KOMP) and International Mouse Phenotyping Consortium (IMPC)
- The Taconic B6 has superior reproductive performance compared to other B6 substrains: superovulated females yield a high number of embryos and males have higher sperm fertilization rates
- The Taconic C57BL/6NTac has proven more amenable to the development of quality embryonic stem cells compared to other B6 substrains
- Popular strain for syngeneic tumor experiments; with a suite of related strains on the same background for mechanistic studies including Rag2, Rag2/OT-I, Rag2/OT-II and many more
- Historical data shows that hydrocephaly occurs in the C57BL/6 mouse in 0.05% of the population and may not be evident until the animal is more than two months of age
Origin
B6 Genetics
Black 6—Guides & Publications
Black 6 Mice Applications & Therapeutic Areas
- ADMET
- Microbiome
- Model Generation Solutions
- Neuroscience
- Oncology & Immuno-Oncology
- Psychiatric Disorders
- Transgenic Model Generation Support
- Vaccine Research
- Autoimmune Disease
- Cardiovascular Disease
- Diabetes
- Immunology
- Infectious Disease
- Inflammation
- Inflammatory Bowel Disease
- Metabolic Disease
Transit, Housing & Welfare
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B6 males at 7+ weeks of age are packed as cagemates, without recombination of animals from different cages into a single Taconic Transit Cage (TTC). We recommend that customers do NOT recombine 7+ week old B6 males from different Taconic Transit Cages into the same cage at or after unpacking.
Packing Practices
Taconic standard practice is to recombine animals of different home cages and/or ages from a single model and sex during packing, except in specific cases where Taconic's animal welfare policy prohibits recombination due to aggression or other concerns. When an order is fulfilled with animals from more than one week of birth, this standard practice results in animals from a range of birth weeks packed together in a single TTC. When an order is fulfilled with animals from genotyped models, this standard practice results in animals from different home cages packed together in a single TTC.
Customers who wish to keep animals from different weeks of birth separated should place orders with the special instruction "Divide and label by age." Note that this special request can result in increased costs for additional Taconic Transit Cages, dividers and/or freight charges.
Taconic discourages other types of custom packing requests as they can have a negative impact on animal welfare. Learn more.
B6 Mouse Diet
Pregnant Mice and Rats Policy
Taconic's breeding specialists use proven, highly effective procedures to generate timed pregnant mice and rats. While gestational age cannot be determined with total precision, strict adherence to pre-defined mating procedures, and close monitoring of female mice and rats after they are co-housed with males, can accurately define the 24-hour period during which mating, and presumably, conception occurs.
Procedures
- At Taconic, the day of sperm cell detection in females is called the sperm-positive date and is considered Day 1 of gestation.
- After co-housing females with males the prior day, Taconic technicians take vaginal swabs of females between 7 and 10 a.m. daily or do plug checks, depending on the model to confirm that mating has occurred. This procedure assumes that timed-pregnant females have mated and conception has occurred from 0 to 24 hours before the designated sperm-positive date.
- Presumably, the majority of matings occur around the midpoint of the previous day's dark cycle, from 6 P.M. to 6 A.M.
- When investigators order timed-pregnant animals at a specified developmental age for delivery on a specific date, Taconic technicians select animals based on the sperm-positive date. For instance, for an order for rats bearing embryos at Day 15 of gestational age for delivery on January 15, Taconic would select timed-pregnant females with a sperm-positive date of January 1.
- Since Taconic's method for selecting timed-pregnant females results in full-term pregnancies with a high success rate as evidenced by the chart below, extra mice and rats are not supplied with each order. However, spontaneous abortions and small litters do occur on occasion. In addition, animals under 14 days do not allow for a visual confirmation of pregnancy and cannot be palpated to confirm pregnancy. When expending considerable time and resources to prepare for a study using timed-pregnant mice or rats on a specific day, and especially when requiring a specific number of pups to be born on a particular day or using a small number of dams or fetuses, please be sure to order additional animals. Please see the chart below to assist in determining the appropriate number of animals to order for your study.
Tips for Ordering
- Specify the sperm-positive date when ordering timed pregnant models.
- Taconic advises customers to order extra timed pregnant animals to prevent any potential issues.
Pregnant Animal Recommendations and Policies
- Taconic's Timed Pregnant Sprague Dawley® rats exhibit greater than 95% accuracy for timing of gestational age. Taconic recommends orders for pregnant mice be less than 18 days gestation, and orders for pregnant rats be less than 19 days in order to prevent the animals from delivering in transit.
Model Type Under 14 days Gestation 14+ days Gestation SD Rats 95% 100% Outbred Mice 75% 100% Inbred Mice 60% 75% - If problems regarding gestational age or pregnancy with timed pregnant orders, customers should immediately contact Taconic's Customer Service Department to provide information regarding the number of animals involved and how non-pregnancy or mistiming was determined. Whenever possible, necropsy information and pictures should be provided to assist complaint investigations for a root cause. Taconic will issue the appropriate credit based on our investigation.
- All untimed pregnant orders are filled using visibly pregnant females selected from Production Colony breeders. Customers should be aware that untimed pregnant mice and rats may deliver their litters while in transit and that no assurances are given regarding the size of the litter.
- Services
Data
Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6NTac mice
Representative data for Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6NTac provided by Biomodels. Download the full data package.
C57BL/6NTac substrains carry the Crb1Rd8 mutation.Retinal degeneration 8, is a mild form of retinal degeneration that affects vision. This recessive mutation is a single base pair mutation in the Crb1 gene, Crb1Rd8 (Mehalow et al. 2003) The onset of the phenotype appears to be between 2 and 6 weeks of age (Pritchett-Corning, 2012).
C57BL/6J mice present a deletion (~17 Kbp) in the Nicotinamide Nucleotide Transhydrogenase (Nnt) gene. Nnt is a transmembrane protein that catalyzes the inter conversion of NADH and NADPH in the mitochondria. Studies suggest that the presence of Nnt is essential for mitochondrial defense against oxidative stress and for normal cellular metabolism (Huang et al. 2006). Taconic’s C57BL mice, including C57BL/6JBomTac, C57BL/6NTac and C57BL/10SgSnAiTac, or our B6D2F1 and B6129F1, do not carry the Nnt mutation which is present in C57BL/6J sub-strain.
C57BL/6J mice present a deletion (~17 Kbp) in the Nicotinamide Nucleotide Transhydrogenase (Nnt) gene. Nnt is a transmembrane protein that catalyzes the inter conversion of NADH and NADPH in the mitochondria. Studies suggest that the presence of Nnt is essential for mitochondrial defense against oxidative stress and for normal cellular metabolism (Huang et al. 2006). Taconic’s C57BL mice, including C57BL/6JBomTac, C57BL/6NTac and C57BL/10SgSnAiTac, or our B6D2F1 and B6129F1, do not carry the Nnt mutation which is present in C57BL/6J sub-strain.
Physiologic
Immunology
Reproductive Data
- Average litter size: 6-8
- Mean # litters/female: 7
- Mean age breeder retired: 10 months
- Mean # days to litter: 22
For some applications, weight may be critical. For orders where weight is critical, please place orders by weight, not by age. Taconic can accept orders by weight for this model. For orders sourced from US or Denmark a production minimum 3 gram span is accepted. All weights are weights at time of packing. Mice and rats can lose weight in transit. Orders for specific weight spans will be assessed a nominal fee. More detail on weight order policies is available.
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n = 500 per sex at MPF, RF and EF health standards from all global colonies. GF mice will typically weigh slightly less than the weights above.
High and low represents mean +/- 2 standard deviations
Based on sample size, the charts above represent ~90% of the population.
All growth curves represent animals housed in our barriers, at our standard density and fed NIH31-M diet. Variations at customer facilities will alter expected growth curves.
Growth charts are provided only as a guide, if a specific weight criteria is needed please order animals by weight.
Customize this chart by clicking the legend elements.
- Licensing
- Pricing - USD
- Pricing - EUR
- Pricing - DKK
- Pricing - USD Nonprofit
- Pricing - EUR Nonprofit
- Pricing - DKK Nonprofit
- Select my Health Standard
- Get Custom Pricing Guide
Licensing
Terms of Sale and Use for Black 6 (B6NTac)
Germ Free Black 6 are sold subject to Taconic's Terms and Conditions for Taconic's Models, Products and Services and the following terms of use:- For-profit purchasers may not breed Germ Free Black 6 except to obtain embryos or fetuses for research use.
- Non-profit purchasers may breed Germ Free Black 6 for use in projects at purchaser's institution and on behalf of non-profit researchers only.
- Germ Free Black 6, progeny and materials derived from them will not be distributed to third parties.
Pricing - USD
Murine Pathogen Free (MPF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | US$33.00 | US$30.00 |
| 5 to 8 | US$39.50 | US$35.25 |
| 9 to 10 | US$47.75 | US$43.75 |
| 11 to 12 | US$55.00 | US$48.75 |
| 13 to 14 | US$74.25 | US$73.75 |
| 15 to 16 | US$84.50 | US$84.50 |
| 17 to 18 | US$96.25 | US$96.25 |
| 19 to 20 | US$108.25 | US$108.25 |
| 21 to 22 | US$119.50 | US$119.50 |
| 23 to 24 | US$129.75 | US$129.75 |
| 25 to 26 | US$141.00 | US$141.00 |
| 27 to 31 | US$164.75 | US$164.75 |
| 32 to 36 | US$187.00 | US$187.00 |
| 37 to 40 | US$210.00 | US$210.00 |
| 41 to 44 | US$231.75 | US$231.75 |
| 45 to 48 | US$254.50 | US$254.50 |
| 49 to 52 | US$277.00 | US$277.00 |
Specialized Inventory
| B6-FL | Quantity 1 - 199 |
|---|---|
| female with litter | US$348.50 |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | US$58.75 |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | US$33.00 | US$30.00 |
| 5 to 8 | US$39.50 | US$35.25 |
| 9 to 10 | US$47.75 | US$43.75 |
| 11 to 12 | US$62.50 | US$48.75 |
| 13 to 14 | US$74.25 | US$74.25 |
| 15 to 16 | US$84.50 | US$84.50 |
| 17 to 18 | US$96.25 | US$96.25 |
| 19 to 20 | US$108.25 | US$108.25 |
| 21 to 22 | US$119.50 | US$119.50 |
| 23 to 24 | US$129.75 | US$129.75 |
| 25 to 26 | US$141.00 | US$141.00 |
| 27 to 31 | US$164.75 | US$164.75 |
| 32 to 36 | US$187.00 | US$187.00 |
| 37 to 40 | US$210.00 | US$210.00 |
| 41 to 44 | US$231.75 | US$231.75 |
| 45 to 48 | US$254.50 | US$254.50 |
| 49 to 52 | US$277.00 | US$277.00 |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | US$58.75 |
Opportunist Free (OF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | US$58.50 |
| 5 to 6 | US$73.25 |
| 7 to 8 | US$85.25 |
| 9 to 10 | US$95.25 |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | US$92.50 |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | US$58.50 |
| 5 to 6 | US$73.25 |
| 7 to 8 | US$85.25 |
| 9 to 10 | US$95.25 |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | US$92.50 |
Germ Free (GF) Health Standard
B6 Female
B6-F
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | US$320.25 |
| 5 | US$342.25 |
| 6 | US$374.50 |
| 7 | US$405.50 |
| 8 | US$436.75 |
| 9 | US$457.50 |
| 10 | US$478.50 |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | US$592.75 |
B6 Male
B6-M
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | US$320.25 |
| 5 | US$342.25 |
| 6 | US$374.50 |
| 7 | US$405.50 |
| 8 | US$436.75 |
| 9 | US$457.50 |
| 10 | US$478.50 |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | US$592.75 |
Pricing - EUR
Murine Pathogen Free (MPF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | 22,25 € | 21,00 € |
| 5 to 8 | 24,25 € | 22,25 € |
| 9 to 10 | 30,75 € | 28,50 € |
| 11 to 12 | 38,00 € | 34,75 € |
| 13 to 14 | 67,25 € | 67,25 € |
| 15 to 16 | 77,00 € | 77,00 € |
| 17 to 18 | 87,50 € | 87,50 € |
| 19 to 20 | 98,00 € | 98,00 € |
| 21 to 22 | 108,25 € | 108,25 € |
| 23 to 24 | 117,75 € | 117,75 € |
| 25 to 26 | 128,25 € | 128,25 € |
| 27 to 31 | 149,75 € | 149,75 € |
| 32 to 36 | 169,00 € | 169,00 € |
| 37 to 40 | 190,25 € | 190,25 € |
| 41 to 44 | 210,00 € | 210,00 € |
| 45 to 48 | 230,50 € | 230,50 € |
| 49 to 52 | 250,00 € | 250,00 € |
Specialized Inventory
| B6-FL | Quantity 1 - 199 |
|---|---|
| female with litter | 312,00 € |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | 52,75 € |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | 22,25 € | 21,00 € |
| 5 to 8 | 24,25 € | 22,25 € |
| 9 to 10 | 30,75 € | 28,50 € |
| 11 to 12 | 38,00 € | 34,75 € |
| 13 to 14 | 67,25 € | 67,25 € |
| 15 to 16 | 77,00 € | 77,00 € |
| 17 to 18 | 87,50 € | 87,50 € |
| 19 to 20 | 98,00 € | 98,00 € |
| 21 to 22 | 108,25 € | 108,25 € |
| 23 to 24 | 117,75 € | 117,75 € |
| 25 to 26 | 128,25 € | 128,25 € |
| 27 to 31 | 149,75 € | 149,75 € |
| 32 to 36 | 169,00 € | 169,00 € |
| 37 to 40 | 190,25 € | 190,25 € |
| 41 to 44 | 210,00 € | 210,00 € |
| 45 to 48 | 230,50 € | 230,50 € |
| 49 to 52 | 250,00 € | 250,00 € |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | 52,75 € |
Opportunist Free (OF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | 37,00 € |
| 5 to 6 | 40,25 € |
| 7 to 8 | 44,25 € |
| 9 to 10 | 50,75 € |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | 83,50 € |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | 37,00 € |
| 5 to 6 | 40,25 € |
| 7 to 8 | 44,25 € |
| 9 to 10 | 50,75 € |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | 83,50 € |
Germ Free (GF) Health Standard
B6 Female
B6-F
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | 288,50 € |
| 5 | 307,00 € |
| 6 | 337,75 € |
| 7 | 365,75 € |
| 8 | 393,50 € |
| 9 | 412,00 € |
| 10 | 432,50 € |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | 535,50 € |
B6 Male
B6-M
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | 288,50 € |
| 5 | 307,00 € |
| 6 | 337,75 € |
| 7 | 365,75 € |
| 8 | 393,50 € |
| 9 | 412,00 € |
| 10 | 432,50 € |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | 535,50 € |
Pricing - DKK
Murine Pathogen Free (MPF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | kr.220,50 | kr.196,75 |
| 5 to 8 | kr.274,00 | kr.234,75 |
| 9 to 10 | kr.322,50 | kr.291,50 |
| 11 to 12 | kr.369,00 | kr.328,00 |
| 13 to 14 | kr.502,25 | kr.502,25 |
| 15 to 16 | kr.571,00 | kr.571,00 |
| 17 to 18 | kr.651,00 | kr.651,00 |
| 19 to 20 | kr.727,75 | kr.727,75 |
| 21 to 22 | kr.804,50 | kr.804,50 |
| 23 to 24 | kr.876,25 | kr.876,25 |
| 25 to 26 | kr.953,25 | kr.953,25 |
| 27 to 31 | kr.1.107,00 | kr.1.107,00 |
| 32 to 36 | kr.1.260,75 | kr.1.260,75 |
| 37 to 40 | kr.1.414,50 | kr.1.414,50 |
| 41 to 44 | kr.1.568,25 | kr.1.568,25 |
| 45 to 48 | kr.1.711,75 | kr.1.711,75 |
| 49 to 52 | kr.1.865,50 | kr.1.865,50 |
Specialized Inventory
| B6-FL | Quantity 1 - 199 |
|---|---|
| female with litter | kr.2.317,50 |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | kr.391,50 |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | kr.220,50 | kr.196,75 |
| 5 to 8 | kr.274,00 | kr.234,75 |
| 9 to 10 | kr.322,50 | kr.291,50 |
| 11 to 12 | kr.422,25 | kr.328,00 |
| 13 to 14 | kr.502,25 | kr.502,25 |
| 15 to 16 | kr.571,00 | kr.571,00 |
| 17 to 18 | kr.651,00 | kr.651,00 |
| 19 to 20 | kr.727,75 | kr.727,75 |
| 21 to 22 | kr.804,50 | kr.804,50 |
| 23 to 24 | kr.876,25 | kr.876,25 |
| 25 to 26 | kr.953,25 | kr.953,25 |
| 27 to 31 | kr.1.107,00 | kr.1.107,00 |
| 32 to 36 | kr.1.260,75 | kr.1.260,75 |
| 37 to 40 | kr.1.414,50 | kr.1.414,50 |
| 41 to 44 | kr.1.568,25 | kr.1.568,25 |
| 45 to 48 | kr.1.711,75 | kr.1.711,75 |
| 49 to 52 | kr.1.865,50 | kr.1.865,50 |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | kr.391,50 |
Opportunist Free (OF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | kr.276,00 |
| 5 to 6 | kr.298,75 |
| 7 to 8 | kr.329,50 |
| 9 to 10 | kr.377,00 |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | kr.621,00 |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | kr.276,00 |
| 5 to 6 | kr.298,75 |
| 7 to 8 | kr.329,50 |
| 9 to 10 | kr.377,00 |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | kr.621,00 |
Germ Free (GF) Health Standard
B6 Female
B6-F
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | kr.2.145,50 |
| 5 | kr.2.283,50 |
| 6 | kr.2.513,25 |
| 7 | kr.2.720,25 |
| 8 | kr.2.927,25 |
| 9 | kr.3.065,25 |
| 10 | kr.3.218,75 |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | kr.3.985,00 |
B6 Male
B6-M
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | kr.2.145,50 |
| 5 | kr.2.283,50 |
| 6 | kr.2.513,25 |
| 7 | kr.2.720,25 |
| 8 | kr.2.927,25 |
| 9 | kr.3.065,25 |
| 10 | kr.3.218,75 |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | kr.3.985,00 |
Pricing - USD Nonprofit
Murine Pathogen Free (MPF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | US$33.00 | US$30.00 |
| 5 to 8 | US$41.50 | US$35.25 |
| 9 to 10 | US$47.75 | US$43.75 |
| 11 to 12 | US$55.00 | US$48.75 |
| 13 to 14 | US$74.25 | US$74.25 |
| 15 to 16 | US$84.50 | US$84.50 |
| 17 to 18 | US$96.25 | US$96.25 |
| 19 to 20 | US$108.25 | US$108.25 |
| 21 to 22 | US$119.50 | US$119.50 |
| 23 to 24 | US$129.75 | US$129.75 |
| 25 to 26 | US$141.00 | US$141.00 |
| 27 to 31 | US$164.75 | US$164.75 |
| 32 to 36 | US$187.00 | US$187.00 |
| 37 to 40 | US$210.00 | US$210.00 |
| 41 to 44 | US$231.75 | US$231.75 |
| 45 to 48 | US$254.50 | US$254.50 |
| 49 to 52 | US$277.00 | US$277.00 |
Specialized Inventory
| B6-FL | Quantity 1 - 199 |
|---|---|
| female with litter | US$348.50 |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | US$58.75 |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | US$33.00 | US$30.00 |
| 5 to 8 | US$41.50 | US$35.25 |
| 9 to 10 | US$47.75 | US$43.75 |
| 11 to 12 | US$62.50 | US$48.75 |
| 13 to 14 | US$74.25 | US$74.25 |
| 15 to 16 | US$84.50 | US$84.50 |
| 17 to 18 | US$96.25 | US$96.25 |
| 19 to 20 | US$108.25 | US$108.25 |
| 21 to 22 | US$119.50 | US$119.50 |
| 23 to 24 | US$129.75 | US$129.75 |
| 25 to 26 | US$141.00 | US$141.00 |
| 27 to 31 | US$164.75 | US$164.75 |
| 32 to 36 | US$187.00 | US$187.00 |
| 37 to 40 | US$210.00 | US$210.00 |
| 41 to 44 | US$231.75 | US$231.75 |
| 45 to 48 | US$254.50 | US$254.50 |
| 49 to 52 | US$277.00 | US$277.00 |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | US$58.75 |
Opportunist Free (OF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | US$58.50 |
| 5 to 6 | US$73.25 |
| 7 to 8 | US$85.25 |
| 9 to 10 | US$95.25 |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | US$92.50 |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | US$58.50 |
| 5 to 6 | US$73.25 |
| 7 to 8 | US$85.25 |
| 9 to 10 | US$95.25 |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | US$92.50 |
Germ Free (GF) Health Standard
B6 Female
B6-F
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | US$265.25 |
| 5 | US$288.00 |
| 6 | US$310.00 |
| 7 | US$330.75 |
| 8 | US$352.50 |
| 9 | US$384.75 |
| 10 | US$416.00 |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | US$592.75 |
B6 Male
B6-M
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | US$265.25 |
| 5 | US$288.00 |
| 6 | US$310.00 |
| 7 | US$330.75 |
| 8 | US$352.50 |
| 9 | US$384.75 |
| 10 | US$416.00 |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | US$592.75 |
Pricing - EUR Nonprofit
Murine Pathogen Free (MPF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | 22,25 € | 21,00 € |
| 5 to 8 | 24,25 € | 22,25 € |
| 9 to 10 | 30,75 € | 28,50 € |
| 11 to 12 | 38,00 € | 34,75 € |
| 13 to 14 | 67,25 € | 67,25 € |
| 15 to 16 | 77,00 € | 77,00 € |
| 17 to 18 | 87,50 € | 87,50 € |
| 19 to 20 | 98,00 € | 98,00 € |
| 21 to 22 | 108,25 € | 108,25 € |
| 23 to 24 | 117,75 € | 117,75 € |
| 25 to 26 | 128,25 € | 128,25 € |
| 27 to 31 | 149,75 € | 149,75 € |
| 32 to 36 | 169,00 € | 169,00 € |
| 37 to 40 | 190,25 € | 190,25 € |
| 41 to 44 | 210,00 € | 210,00 € |
| 45 to 48 | 230,50 € | 230,50 € |
| 49 to 52 | 250,00 € | 250,00 € |
Specialized Inventory
| B6-FL | Quantity 1 - 199 |
|---|---|
| female with litter | 312,00 € |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | 52,75 € |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | 22,25 € | 21,00 € |
| 5 to 8 | 24,25 € | 22,25 € |
| 9 to 10 | 30,75 € | 28,50 € |
| 11 to 12 | 38,00 € | 34,75 € |
| 13 to 14 | 67,25 € | 67,25 € |
| 15 to 16 | 77,00 € | 77,00 € |
| 17 to 18 | 87,50 € | 87,50 € |
| 19 to 20 | 98,00 € | 98,00 € |
| 21 to 22 | 108,25 € | 108,25 € |
| 23 to 24 | 117,75 € | 117,75 € |
| 25 to 26 | 128,25 € | 128,25 € |
| 27 to 31 | 149,75 € | 149,75 € |
| 32 to 36 | 169,00 € | 169,00 € |
| 37 to 40 | 190,25 € | 190,25 € |
| 41 to 44 | 210,00 € | 210,00 € |
| 45 to 48 | 230,50 € | 230,50 € |
| 49 to 52 | 250,00 € | 250,00 € |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | 52,75 € |
Opportunist Free (OF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | 37,00 € |
| 5 to 6 | 40,25 € |
| 7 to 8 | 44,25 € |
| 9 to 10 | 50,75 € |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | 83,50 € |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | 37,00 € |
| 5 to 6 | 40,25 € |
| 7 to 8 | 44,25 € |
| 9 to 10 | 50,75 € |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | 83,50 € |
Germ Free (GF) Health Standard
B6 Female
B6-F
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | 241,00 € |
| 5 | 259,50 € |
| 6 | 278,00 € |
| 7 | 298,75 € |
| 8 | 317,25 € |
| 9 | 346,00 € |
| 10 | 375,00 € |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | 535,50 € |
B6 Male
B6-M
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | 241,00 € |
| 5 | 259,50 € |
| 6 | 278,00 € |
| 7 | 298,75 € |
| 8 | 317,25 € |
| 9 | 346,00 € |
| 10 | 375,00 € |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | 535,50 € |
Pricing - DKK Nonprofit
Murine Pathogen Free (MPF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | kr.220,50 | kr.196,75 |
| 5 to 8 | kr.274,00 | kr.234,75 |
| 9 to 10 | kr.322,50 | kr.291,50 |
| 11 to 12 | kr.369,00 | kr.328,00 |
| 13 to 14 | kr.502,25 | kr.502,25 |
| 15 to 16 | kr.571,00 | kr.571,00 |
| 17 to 18 | kr.651,00 | kr.651,00 |
| 19 to 20 | kr.727,75 | kr.727,75 |
| 21 to 22 | kr.804,50 | kr.804,50 |
| 23 to 24 | kr.876,25 | kr.876,25 |
| 25 to 26 | kr.953,25 | kr.953,25 |
| 27 to 31 | kr.1.107,00 | kr.1.107,00 |
| 32 to 36 | kr.1.260,75 | kr.1.260,75 |
| 37 to 40 | kr.1.414,50 | kr.1.414,50 |
| 41 to 44 | kr.1.568,25 | kr.1.568,25 |
| 45 to 48 | kr.1.711,75 | kr.1.711,75 |
| 49 to 52 | kr.1.865,50 | kr.1.865,50 |
Specialized Inventory
| B6-FL | Quantity 1 - 199 |
|---|---|
| female with litter | kr.2.317,50 |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | kr.391,50 |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 199 | Quantity 200 - 999 |
|---|---|---|
| 3 to 4 | kr.220,50 | kr.196,75 |
| 5 to 8 | kr.274,00 | kr.234,75 |
| 9 to 10 | kr.322,50 | kr.291,50 |
| 11 to 12 | kr.422,25 | kr.328,00 |
| 13 to 14 | kr.502,25 | kr.502,25 |
| 15 to 16 | kr.571,00 | kr.571,00 |
| 17 to 18 | kr.651,00 | kr.651,00 |
| 19 to 20 | kr.727,75 | kr.727,75 |
| 21 to 22 | kr.804,50 | kr.804,50 |
| 23 to 24 | kr.876,25 | kr.876,25 |
| 25 to 26 | kr.953,25 | kr.953,25 |
| 27 to 31 | kr.1.107,00 | kr.1.107,00 |
| 32 to 36 | kr.1.260,75 | kr.1.260,75 |
| 37 to 40 | kr.1.414,50 | kr.1.414,50 |
| 41 to 44 | kr.1.568,25 | kr.1.568,25 |
| 45 to 48 | kr.1.711,75 | kr.1.711,75 |
| 49 to 52 | kr.1.865,50 | kr.1.865,50 |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | kr.391,50 |
Opportunist Free (OF) Health Standard
B6 Female
B6-F
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | kr.276,00 |
| 5 to 6 | kr.298,75 |
| 7 to 8 | kr.329,50 |
| 9 to 10 | kr.377,00 |
Specialized Inventory
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | kr.621,00 |
B6 Male
B6-M
Available now
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 4 | kr.276,00 |
| 5 to 6 | kr.298,75 |
| 7 to 8 | kr.329,50 |
| 9 to 10 | kr.377,00 |
Specialized Inventory
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | kr.621,00 |
Germ Free (GF) Health Standard
B6 Female
B6-F
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | kr.1.793,25 |
| 5 | kr.1.931,25 |
| 6 | kr.2.069,25 |
| 7 | kr.2.222,75 |
| 8 | kr.2.360,75 |
| 9 | kr.2.575,00 |
| 10 | kr.2.789,25 |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RF | Quantity 1 - 199 |
|---|---|
| retired female breeder | kr.3.985,00 |
B6 Male
B6-M
Germ-free animals may require additional time for delivery.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 4 | kr.1.793,25 |
| 5 | kr.1.931,25 |
| 6 | kr.2.069,25 |
| 7 | kr.2.222,75 |
| 8 | kr.2.360,75 |
| 9 | kr.2.575,00 |
| 10 | kr.2.789,25 |
Specialized Inventory
Germ-free animals may require additional time for delivery.
| B6-RM | Quantity 1 - 199 |
|---|---|
| retired male breeder | kr.3.985,00 |
Select my Health Standard
Need help choosing the right Taconic Biosciences health standard for your research?
Use the Health Standard Selector to enter your exclusion list. The tool will tell you which health standards meet your requirements.
Get custom pricing guide
Why Use B6 (C57BL/6) Mice for Your Research Studies?
Black 6 (C57BL/6) mice are the preferred choice for many researchers because of their proven track record in various research applications. These genetically uniform mice ensure that your experiments are not affected by genetic variability, allowing for clear and reliable data. Whether working in genetics, pharmacology, or other areas, B6 mice deliver exceptional quality and consistency, making them the gold standard for preclinical studies.
When it comes to B6 mice, Taconic Biosciences is your trusted partner. With decades of experience in breeding and maintaining high-quality mouse models, Taconic ensures that every Black 6 (C57BL/6) mouse meets the strictest standards for genetic purity and health. Researchers can count on Taconic’s rigorous breeding programs and quality control procedures to provide genetically accurate, healthy mice for their studies.
B6 (C57BL/6) Mice for Immunology, Oncology, and Neuroscience Research
The Black 6 mouse model is a cornerstone in research across immunology, oncology and immuno-oncology, and neuroscience. With its genetically stable background, C57BL/6 mice provide consistent and reliable data that are essential for studying complex biological systems. In immunology, they are frequently used to investigate immune responses and autoimmune diseases, offering insights into therapeutic interventions. In cancer research, B6 mice serve as a critical tool for modeling cancer progression and testing new cancer therapies. Their application in neuroscience research is equally important, enabling the study of neurodegenerative diseases, neuroinflammation, and brain function. The versatile and predictable nature of the B6 strain makes it an invaluable resource for advancing research in these diverse and rapidly evolving fields.
Order High-Quality Black 6 (C57BL/6) Mice for Your Biomedical Research
C57BL/6 (B6) mice are the trusted choice for researchers seeking consistency and reliability in preclinical studies. Taconic Biosciences offers B6 mice of exceptional quality, ready to support your next study. Order today to streamline your research.
Related Models
Customer Reviews and Testimonials—Hear From our Scientists
“Hooke uses the Taconic B6 because we get more consistent disease development for Experimental Autoimmune Encephalomyelitis (EAE) than when using mice from other vendors.”
— Hooke Laboratories
“Taconic Biosciences had provided invaluable support to our course on "Mouse Development, Stem Cells & Cancer". It would be difficult to continue to teach this course at the level we currently do without Taconic's expertise and C57BL/6 mice.”
— Cold Spring Harbor
- Section 1
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Smart Select Program
Free Animal Model Trial: Quality & Compatibility Assurance
To help alleviate uncertainty in selecting a new model, we offer a free animal trial program that allows you to test the quality, consistency, and availability of Taconic’s rodent models. Pilot our most popular mouse or rat models in your facility at no cost to your organization with the Smart Select program.
- Evaluate a specific model strain, before making any financial investment
- Request up to 20 animals from one of the strains listed here to test for quality, consistency, and suitability for your experimental purpose
- Enjoy free ground shipping, where applicable (see table for more details)