About the webinar:
Obesity and its related comorbidities, including MASH, cardiovascular disease, and metabolic dysfunction are rapidly evolving areas of drug development, driven by increasingly complex therapeutic approaches. As these therapies advance, traditional single-model strategies are often insufficient to fully capture disease biology or generate translatable insights.
In this webinar, Laura Griffin, Associate Director of Cardiometabolic Portfolio at Taconic Biosciences, presents a practical framework for building more clinically relevant preclinical studies by integrating diet conditioning, genetic models, and study design.
Key topics include:
- Establishing study-ready disease states through controlled diet conditioning and cohort standardization
- Leveraging genetically engineered models, including humanized GLP-1 receptor models, to better align with therapeutic targets
- Designing integrated cohort design strategies that combine genetics, diet, and phenotype monitoring
In addition to focusing on individual models, this session highlights how to assemble the right combination of tools to better reflect human disease and support more confident decision-making in cardiometabolic research.