Tau Control

Mixed Background

  • Model #
  • Genotype
  • Nomenclature
  • 18392-F
    wt/wt
    STOCK (SW and B6D2F1)
  • 18392-M
    wt/wt
    STOCK (SW and B6D2F1)
  • Wild type control stock for Tau (model #2508).
  • This model does NOT express human Tau.
  • Model is on a C57BL/6, DBA/2, SW mixed background.
  • Model was generated via a genetic refresh of model #2508. See Origin below for more information.
  • Pink eyed animals, associated with certain coat colors, and the Pde6brd1 retinal degeneration mutation can cause light sensitivity and/or blindness in some animals. This may impact the results of behavioral testing. Upon request, animals can be screened for eye color, coat color, and/or rd1 homozygosity for an additional fee.
Orders by weight: Taconic cannot accept orders by weight for this model. Please note that shipments may contain animals with a larger weight variation.

Genetic Background:

C57BL/6, DBA/2, SW mixed background

Origin:

This control stock was generated via a genetic refresh of model #2508. Homozygous 2508 females were mated to Swiss Webster males. Hemizygous males from this cross were mated to B6D2F1 females. Wild type offspring from this second cross were used to establish control model #18392, whereas hemizygous males and females were intracrossed to generate homozygous mice to re-establish model #2508.


Genetics:

Wild type for Nnt mutation; carries Pde6brd1 mutation.


Color:

Various

Species:

Mouse


Conditions of Use for Taconic Transgenic Models™
Taconic Transgenic Models™ (Models) are produced and distributed under rights to patents and intellectual property licensed from various institutions. Taconic sells the Models to purchasers, grants to each purchaser a right under Taconic's rights in such licensed patents and intellectual property to use the purchased Model in consideration of purchasers' acknowledgement of and agreement to the Terms and Conditions for Taconic Models, Products and Services and the following terms of use:
  • Title to these Models and biological materials derived from them remains with Taconic.
  • The Models will be used for research purposes only.
  • The Models will not be bred or cross-bred except to obtain embryos or fetuses required for research purposes unless additional rights have been granted in writing by Taconic.
  • The Models and biological materials derived from them will not be distributed to third parties or used for commercial purposes.
  • Non-profit purchasers may not use this Model and/or biological materials derived from it in sponsored research or contract research studies unless it is purchased at the for-profit price.
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