Recently, Taconic Biosciences's Senior Manager of Global Application Sciences, Dr. Philip Dubé, was interviewed by News Medical about genetically engineered mice for neuroscience research. Dubé begins by stating that "a very good mouse model does not mean that that is available [or appropriate] for drug development." Additionally, since there are so many animal models currently on the market, Dubé points out that it is imperative that clients work with a reputable model generation company to obtain the most suitable model for their needs:
"The first challenge is access to animal models. There are a lot of licensing issues when it comes to using animal models. Furthermore, the development of a very good mouse model does not mean that that is available for drug development.
Secondly, choosing the right type of model can be a challenge. A mouse model will recapitulate some aspects of a disease, but not all. The question then becomes how to choose the right one for your specific target of interest. There are limitations to some animal models, and every year new ones are being created." Read the complete article at: News-medical.net
"The first challenge is access to animal models. There are a lot of licensing issues when it comes to using animal models. Furthermore, the development of a very good mouse model does not mean that that is available for drug development. Secondly, choosing the right type of model can be a challenge. A mouse model will recapitulate some aspects of a disease, but not all. The question then becomes how to choose the right one for your specific target of interest. There are limitations to some animal models, and every year new ones are being created."