Taconic Biosciences maintains an inventory of C57BL/6NTac male mice on 60% kcal high fat irradiated diet. Taconic uses Research Diets industry standard high fat rodent diet,
. C57BL/6NTac males are put on special diet at 6 weeks of
age and housed at reduced density. Control males are housed in the same location, also at reduced density, and are fed NIH-31M diet
Control males can also be generated using a low fat purified diet upon request
about customized Diet Induced Obese (DIO) models using any of Taconic's commercial animal models.
Custom Diet Protocols can use any diet manufactured according to client specifications. Client test articles can be incorporated into standard or custom feeds.
DIO mice in transit for an extended period of time (more than 48 hours) can lose 20-25% of their body weight and reach a new weight set point, making them resistant to high fat diet when they arrive. Taconic will only ship mice that have previously responded to DIO, but due to this known phenotype we suggest ordering an additional 5-10% in order to make sure you have a sufficient number of animals for your study.